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point decrease » point increase (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
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40061
Core–Shell {Mn<sub>7</sub>⊂(Mn,Cd)<sub>12</sub>} Assembled from Core {Mn<sub>7</sub>} Disc
Published 2017“…HR-ESI-MS was even more precise by revealing three prominent molecular species, Mn<sub>13</sub>Cd<sub>6</sub>, Mn<sub>14</sub>Cd<sub>5</sub> and Mn<sub>15</sub>Cd<sub>4</sub>, having a distribution of metals. …”
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40062
Genetic Polymorphisms in XRCC1, CD3EAP, PPP1R13L, XPB, XPC, and XPF and the Risk of Chronic Benzene Poisoning in a Chinese Occupational Population
Published 2015“…However, the T allele in PPP1R13L rs1005165 (P<0.05) and the GA allele in CD3EAP rs967591 (OR = 0.162; 95% CI: 0039~0.666; <i>P</i> = 0.037) decreased the risk of CBP in men. The haplotype analysis of XRCC1 indicated that XRCC1 rs25487<sup>A</sup>, rs25489<sup>G</sup> and rs1799782<sup>T</sup> (OR = 15.469; 95% CI: 5.536–43.225; <i>P</i><0.001) were associated with a high risk of CBP.…”
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40063
<i>miR-146a</i> LNA treatment inhibits OSCC oncogenicity.
Published 2013“…(C) <i>miR-146a</i> LNA treatment decreases the growth of SAS cells (Lt) and OECM-1 cells (Rt) with or without exogenous <i>miR-146a</i> expression. …”
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40064
Efficacy and safety of saxagliptin in combination with insulin in Japanese patients with type 2 diabetes mellitus: a 16-week double-blind randomized controlled trial with a 36-week...
Published 2017“…</p> <p><b>Research design and methods</b>: We randomized 240 patients with type 2 diabetes mellitus on insulin monotherapy to 5-mg saxagliptin or placebo as add-on therapy for a 16-week, double-blind period. …”
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40065
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40066
RPIA regulates colon cell proliferation through β-catenin expression in HCT116 cells.
Published 2018“…<i>AXIN2</i>, <i>Axis inhibition protein 2</i>; <i>CCND1</i>, <i>Cyclin D1</i>; <i>CCNE2</i>, <i>Cyclin E2</i>; <i>CTNNB1</i>, <i>CATENIN BETA 1</i>; pcDNA, pcDNA3 vector control; qPCR, quantitative PCR; RPIA, ribose-5-phosphate isomerase A; si-NC, negative control small interfering RNA; si-RPIA, RPIA small interfering RNA; TCF, T-cell transcription factor.…”
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40067
An idealized view of the opportunity provided by a comparative and integrated oncology drug development path.
Published 2013“…Factoring in additional costs for comparative studies with this approach of US$150,000 for studies conducted in the preclinical setting, US$250,000 for studies conducted before or during Phases I–II human trials and US$1 million for studies conducted before Phases II–III studies, the total cost of development is estimated at US$2.07 billion. The result may be a decrease in average clinical trial costs per approved drug from US$290 million to US$173 million <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1000161#pmed.1000161-Adams1" target="_blank">[5]</a>.…”
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40068
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40069
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40070
Diabetes, Drug Treatment and Mortality in COVID-19: A Multinational Retrospective Cohort Study
Published 2021“…Use of DPP-4 inhibitors was associated with a reduction in respiratory complications (24.0% vs 29.2%; RR, 0.82 [95% CI, 0.74-0.90]; <i>P</i> <.001), and continued use of DPP-4 inhibitors after hospitalization was associated with a decrease in mortality compared with those who discontinued use (9% vs 19%; RR, 0.45 [95% CI, 0.28-0.72]; <i>P</i> <.001). …”
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40071
Data_Sheet_1_Expression of vitamin D receptor, CYP24A1, and CYP27B1 in normal and inflamed canine pancreases.DOCX
Published 2023“…This study showed that VDR expression decreased in inflamed pancreases and demonstrated CYP24A1 and CYP27B1 expression in the canine pancreas for the first time. …”
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40072
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40073
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40074
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40075
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40076
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40077
Tumor volume regression during neoadjuvant chemoradiotherapy for esophageal cancer: a prospective study with weekly MRI
Published 2020“…Tumor volume regression started after the first week of nCRT with a significant decrease in tumor volumes every subsequent week. …”
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40078
Prognostic indicators and survival rates in vulvar cancer: insights from a retrospective study
Published 2025“…Additionally, a tumour size exceeding 4 cm in diameter was significantly linked with decreased OS (<i>p</i> = .001). …”
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40079
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40080
KDM1 revealed typical electrophysiological features of the K<sub>in</sub>-a subclade.
Published 2020“…The measured I<sub>SS</sub> were normalized to −150 mV and 100 mM K<sup>+</sup> at pH 4 (<i>n</i> = 4; mean ± SD). …”