Glibenclamide alters the subsets of T cells in both spleen and pancreatic-draining lymph nodes. by Smaragda Lamprianou (3599570)

“…<p><b>a)</b> After 3 wks of treatment (mice 6 wk of age), FACS analysis showed that the treatment with glibenclamide dose 2 (solid symbols) increased the proportion of the effector subsets of CD44^hiCD62L^- T cells, and decreased that of the naïve subset of CD44^loCD62L⁺ T cells in CD4⁺ (top panel) and CD8⁺ T cells (bottom panel), as compared to control values (open symbols). …”

TLR2 KO Mice Demonstrate Reduced Distant Organ Injury by W. Joost Wiersinga (33895)

“…<p>Mice were intranasally inoculated with 5 × 10² CFU of B. pseudomallei. After 72 h, representative spleen histology of WT (A) and TLR2 KO (B) mice demonstrated decreased inflammation and less thrombus formation in the TLR2 KO spleens. …”

CAF inhibit melanoma invasion in GOF^Notch1 mice. by Hongwei Shao (493627)

“…<p><b>A</b>. <i>Left</i>: decreased tumor invasion in GOF^Notch1 compared with GOF^ctrl mice. …”

Schematic representation of the TRA/TRD locus use. by Florence Thuderoz (366862)

“…A distal V gene is very rarely rearranged with proximal J genes because of the high recombination frequency between proximal V and J genes, leading to the proximal J genes deletion. 1) the first step governing the TRA/TRD locus utilization is defined by the opening of the most proximal V-J region, 2) According that T cells can undergo 1 to 3 secondary rearrangements, the second step giving the V and J accessible windows, is defined by the opening speeds of V and J regions. …”

COWPEA LEAF AREA, BIOMASS PRODUCTION AND PRODUCTIVITY UNDER DIFFERENT WATER REGIMES IN CASTANHAL, PARÁ, BRAZIL by PAULO JORGE DE OLIVEIRA PONTE DE SOUZA (6140720)

“…Growth and productivity data were submitted to analysis of variance with two variation factors (water regime and experimental year) at 5% probability. Student's t -test at 5% probability was used in the means of the stomatal conductance data, since this was monitored only in 2012. …”

Effects of ASM inhibitors on lifespan regulation and enzyme activity in <i>C. elegans</i>. by Yongsoon Kim (132228)

“…<p>Lifespan assays were carried out at 20°C. (A) and (B) Wild-type (N2) animals were plated on plates containing 30 µM desipramine (A), 5 µM clomipramine (B) or vehicle control (0 µM in panel A or B). …”

Workers of the hospital maintenance sector: protection, hearing symptoms and noise exposure by Flávia Elisa Antunes Lemes de Oliveira Ramos (5667182)

“…Noise perception in the maintenance service was medium (53%) and high (44%), evidenced noise levels of 62.0 to 101dB (A). Conclusion: the hearing protector was worn by 59.7% of the workers, the plug model was the most used (47.4%) and 75.8% reported that occupational noise decreased with the use of hearing protectors. …”

Counting of cell nuclei in SD and PKD rats after EPO-treatment. by Stephanie Busch (417837)

“…<p>Four week old heterozygous male PKD rats (n = 4) were treated three times a week with 0.5 ml/kg body weight DynEpo intraperitoneally for four weeks. …”

Effects of loss of UGCG on infections by VSV pseudoviruses bearing the glycoproteins of measles virus, VSV, and EBOV. by Kelly Drews (8423058)

“…Infection by VSV pseudoviruses bearing the EBOV glycoprotein was decreased in both UGCG KO lines tested (mean ± SE; n = 6), also consistent with the results in <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0228735#pone.0228735.g005" target="_blank">Fig 5</a></b>. ** p<0.01 using a Mann-Whitney non-parametric test.…”

Dorsal lateral striatum MSN CaMKII inhibition reduces excitatory transmission independently of changes in release probability. by Jason R. Klug (132807)

“…PPR (50 ms ISI) for EAC3I-containing and EAC3I-lacking MSNs before, during and after application of baclofen (NON EGFP: n = 6; EGFP: n = 5; p = 0.48). (F) Baclofen decreases sEPSC frequency. …”

Characterization of miRNA as the functional immunomodulatory agent. by Duncheng Wang (838084)

“…Values shown are the mean and range of ≥5 animals per group. <b>Panel D:</b> Partial characterization of the tolerogenic TA1-miRNA pattern. miRNA shown represent species with significant variance from the non-tolerogenic (naïve) miRNA preparation (0 value; grey line). …”

<i>Brn3b</i> regulates expression of <i>Tac2</i> in the deep SC/PAG. by Hyoseo Lee (17419987)

“…<b>(C)</b> Assessment of <i>Tac1</i>, <i>Tac2</i>, and <i>Crh</i> levels at P3-P5 showed decreased expression of <i>Tac2</i> in cKO mice. …”

Simulation of Dynamics of Networks with Mutually Inhibitory Operons by Akiko Kashiwagi (67598)

“…</p> <p>Culture conditions were captured by <i>N</i>1, <i>N</i>2 (see Supporting Information). We employed a changing environment: (<i>N</i>1, <i>N</i>2) = (10,10) from 0 to 2000 step, (0,10) to 8000, (10,10) to 10000, (10, 0) to 16000, (10,10) to 20000.…”

Image_1_Both Natural and Induced Anti-Sda Antibodies Play Important Roles in GTKO Pig-to-Rhesus Monkey Xenotransplantation.tif by Hao Feng (54208)

“…Both the overall binding of monkey serum IgM/IgG antibody to GTKO pig PBMCs and CDC against these PBMCs decreased significantly with a progressive reduction in Sda expression, showing a clear dose-effect relationship. …”

Tumor Heterogeneity by Sabrina L Spencer (20366)

“…As the tumor begins to form, there is typically a slow increase in the degree of tissue heterogeneity followed by a sudden increase, an equally sudden decrease, and then often another increase as the tissue reaches 9 × 10⁵ cells.…”

Table_2_Associations Between Change in Outside Time Pre- and Post-COVID-19 Public Health Restrictions and Mental Health: Brief Research Report.pdf by Sydney L. Cindrich (10034066)

“…Participants who increased or maintained outside time following COVID-19 restrictions reported lower stress (p < 0.001, 5.93 [5.74–6.12], Hedges' g = −0.18; p < 0.001, mean = 5.85 [5.67–6.02], Hedges' g = −0.21; respectively) and higher positive mental health (p < 0.001, 24.49 [24.20–24.77], Hedges' g = 0.21; p < 0.001, 24.78 [24.52–25.03], Hedges' g = 0.28) compared to those who decreased outside time. …”

Table_1_Associations Between Change in Outside Time Pre- and Post-COVID-19 Public Health Restrictions and Mental Health: Brief Research Report.pdf by Sydney L. Cindrich (10034066)

“…Participants who increased or maintained outside time following COVID-19 restrictions reported lower stress (p < 0.001, 5.93 [5.74–6.12], Hedges' g = −0.18; p < 0.001, mean = 5.85 [5.67–6.02], Hedges' g = −0.21; respectively) and higher positive mental health (p < 0.001, 24.49 [24.20–24.77], Hedges' g = 0.21; p < 0.001, 24.78 [24.52–25.03], Hedges' g = 0.28) compared to those who decreased outside time. …”

Subaortic Membrane Resection and Septal Myectomy by Amr Alsalakawy (17888560)

“…This video presents the case of a nine-year-old male with severe subvalvular stenosis caused by a discrete SAM and interventricular septum hypertrophy. …”

TUNEL staining and cell proliferation in the OB by Haydn M Prosser (40070)

“…Note, the difference in size of the OB at 5 × magnification. Scale bars: 100 µm (A and B); 20 µm (C); 500 µm (E and F).…”

Cytoskeleton and major extracellular matrix proteins were analyzed by immunofluorescence. by Ludwig Stanislas Loison-Robert (4797525)

“…The observed decrease in type 1 collagen, when DPSC were in contact with biomaterials, was confirmed using RT-qPCR (5J), whereas protein secretion was not modified by the experimental conditions (Fig 5K). …”