Solar hydrogen production via thermochemical magnesium oxide – Magnesium sulfate water splitting cycle حسب Rahul R. Bhosale (6467102)

"…<p dir="ltr">This investigation reports the thermodynamic scrutiny of the MgO/MgSO₄ water-splitting cycle. At the initial stage, the thermal reduction temperature required for the commencement of the thermal dissociation of MgSO₄ (in the absence of inert Ar) and the maximum temperature below which the water-splitting reaction is feasible is identified by performing thermodynamic equilibrium calculations. …"

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit Masania (7164239)

"…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …"

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …"
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Impact of trace noble metals on the catalytic performance of LaNiMgO towards methane dry reforming حسب Mohamed, Assem T.

"…On the other hand, at the same time-on-stream LaNiMgO-Rh lost 0.3 and 0.7 % of its maximum CO2 and CH4 conversions, respectively.In durability measurements, and after 140h LaNiMgO-Rh exhibited slight decay in the CO2 conversion from 77.6 % to 70.5%, the CH4 conversion decreased from 72.3% to 64.2%. …"
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Impact of trace noble metals on the catalytic performance of LaNiMgO towards methane dry reforming حسب Yahia H. Ahmad (14340210)

"…In durability measurements, and after 140h LaNiMgO-Rh exhibited slight decay in the CO₂ conversion from 77.6 % to 70.5%, the CH₄ conversion decreased from 72.3% to 64.2%. …"

Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells حسب Mohamed Qasim, Al-Fahdawi

"…The cytotoxicity of Pt/MgO nanoparticles was determined via the 3-(4,5-dimethylthiazol-2-yl)−2,5-diphenyltetrazolium bromide assay on the human lung and colonic cancer cells (A549 and HT29 respectively) and normal human lung and colonic fibroblasts cells (MRC-5 and CCD-18Co repectively). …"
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Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer حسب Adviti Naik (673163)

"…Silencing LDHC in breast cancer cell lines (MDA-MB-468, BT-549, HCC-1954) enhanced early T cell activation and cytolytic activity. …"

miRNA-dependent regulation of STIM1 expression in breast cancer حسب Rashmi P. Kulkarni (18618634)

"…<p dir="ltr">Store-operated Ca²⁺ entry (SOCE) has been shown to be important for breast cancer metastasis in xenograft mouse models. …"

Characterizing the Protein Coding RNAs (mRNA) and Long Non-Coding RNAs (LncRNAs) in Chemo Resistant Triple Negative Breast Cancer حسب Ahmed Mahmoud Mahmoud Mohamed Kardousha (19926096)

"…Majority of BC overexpress estrogen and progesterone receptors or epidermal growth factor receptors and are referred to as HR+ or HER2+, respectively. Triple negative Breast cancer (TNBC) is another type of BC characterized by the lack of HR and HER2 overexpression. …"

Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells حسب Mohamed Qasim Al-Fahdawi (17844209)

"…The cytotoxicity of Pt/MgO nanoparticles was determined via the 3-(4,5-dimethylthiazol-2-yl)−2,5-diphenyltetrazolium bromide assay on the human lung and colonic cancer cells (A549 and HT29 respectively) and normal human lung and colonic fibroblasts cells (MRC-5 and CCD-18Co repectively). …"

Modulation of SLFN11 induces changes in DNA Damage response in breast cancer حسب Christophe Michel Raynaud (17449906)

"…Our results show that induction of SLFN11 expression can enhance DDA and DDR sensitivity in breast cancer cells and dCas9 systems may represent a novel approach to increase SLFN11 and achieve higher sensitivity to chemotherapeutic agents, improving outcome or decreasing required drug concentrations. …"

Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis حسب Wouter Hendrickx (44559)

"…These findings suggest that mutation-driven perturbations of MAPK pathways are linked to the negative regulation of intratumoral immune response in breast cancer. Modulations of MAPK pathways could be experimentally tested to enhance breast cancer immune sensitivity.…"

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma حسب Peter Kubatka (11008854)

"…In the mouse model, R. coriaria at a higher dose (1%) significantly decreased tumor volume by 27% when compared to controls. …"

Exploring the LDHC Interactome as Novel Candidate Therapeutic Targets to Advance Breast Cancer Precision Medicine حسب Mariam Ahmed Amin Mohamed Elesnawy (21547187)

"…</p><p dir="ltr">Finally, silencing of <i>PKM2 </i>and<i> TUBA1B</i> in breast cancer cells increased DNA damage and decreased cancer cell survival, validating their role in genomic integrity and mimicking our previous observations following silencing of LDHC. …"

Meta-Heuristic Algorithm-Tuned Neural Network for Breast Cancer Diagnosis Using Ultrasound Images حسب Ahila A (18394806)

"…<div><p>Breast cancer is the most menacing cancer among all types of cancer in women around the globe. …"

Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal حسب Zehra Irshad (18614869)

"…Human aortal endothelial cells (HAECs) were incubated in high glucose concentration (20 mM versus 5 mM control) in vitro for 3–6 days. Flux of glucose metabolism, MG formation and glycation and changes in cytosolic protein abundances, MG modification and proteotoxic responses were assessed. …"

CD146, a novel target of CD44-signaling, suppresses breast tumor cell invasion حسب Allal Ouhtit (14153256)

"…While the exact function of CD146 in breast cancer (BC) is not completely understood, substantial evidence from our work and others support the hypothesis that CD146 is a suppressor of breast tumor progression. …"

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications حسب Jingxuan Shan (4711089)

"…In the TCGA TNBC/Basal-like cohort the <b><i>MAP3K21</i></b><b> </b><b>rs1294255-G</b> allele was associated with a decreased OVS. High expression of <i>CCL5</i> in breast tumors was significantly associated with an increased OVS in all BC patients, but particularly in TNBC/Basal-like patients. …"

Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection? حسب Abu Saleh Md Moin (6189512)

"…The Renin-Angiotensin System (RAS) is activated in type 2 diabetes (T2D); therefore, the aim of this study was to determine if hypoglycaemia-induced stress in T2D would potentiate serum NRP1(sNRP1) levels, reflecting an increased risk for SARS-CoV-2 infection.</p><h3>Methods</h3><p dir="ltr">A case-control study of aged-matched T2D (n = 23) and control (n = 23) subjects who underwent a hyperinsulinemic clamp over 1-hour to hypoglycemia(<40mg/dl) with subsequent timecourse of 4-hours and 24-hours. …"

Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression حسب Rayanah Barnawi (8737584)

"…<p dir="ltr">Recent years have witnessed major progress in development of novel therapeutic agents such as chemotherapy, targeted therapy and immune checkpoint inhibitors for breast cancer. However, cancer-related death remains high especially in triple-negative breast cancer (TNBC) due limited therapeutic options. …"