Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit Masania (7164239)

"…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. …"

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes حسب Manjunath Ramanjaneya (14603468)

"…</p><h3>Conclusions</h3><p dir="ltr">Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …"

Solar hydrogen production via thermochemical magnesium oxide – Magnesium sulfate water splitting cycle حسب Rahul R. Bhosale (6467102)

"…<p dir="ltr">This investigation reports the thermodynamic scrutiny of the MgO/MgSO₄ water-splitting cycle. At the initial stage, the thermal reduction temperature required for the commencement of the thermal dissociation of MgSO₄ (in the absence of inert Ar) and the maximum temperature below which the water-splitting reaction is feasible is identified by performing thermodynamic equilibrium calculations. …"

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …"

Impact of trace noble metals on the catalytic performance of LaNiMgO towards methane dry reforming حسب Mohamed, Assem T.

"…On the other hand, at the same time-on-stream LaNiMgO-Rh lost 0.3 and 0.7 % of its maximum CO2 and CH4 conversions, respectively.In durability measurements, and after 140h LaNiMgO-Rh exhibited slight decay in the CO2 conversion from 77.6 % to 70.5%, the CH4 conversion decreased from 72.3% to 64.2%. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Impact of trace noble metals on the catalytic performance of LaNiMgO towards methane dry reforming حسب Yahia H. Ahmad (14340210)

"…In durability measurements, and after 140h LaNiMgO-Rh exhibited slight decay in the CO₂ conversion from 77.6 % to 70.5%, the CH₄ conversion decreased from 72.3% to 64.2%. …"

Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells حسب Mohamed Qasim, Al-Fahdawi

"…The cytotoxicity of Pt/MgO nanoparticles was determined via the 3-(4,5-dimethylthiazol-2-yl)−2,5-diphenyltetrazolium bromide assay on the human lung and colonic cancer cells (A549 and HT29 respectively) and normal human lung and colonic fibroblasts cells (MRC-5 and CCD-18Co repectively). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Studying coral reef patterns in UAE waters using panel data analysis and multinomial logit and probit models حسب Ben Romdhane, Haifa

"…Main findings, based on the studied data, showed that nutrient enrichment, a proxy for anthropogenic pressure, and salinity are the most influential factors to induce coral damage in UAE waters. Furthermore, results demonstrated that the probability of severe damage increases with decreasing water oxygenation and with increasing temperature, light, salinity, acidity and nutrient levels. …"
احصل على النص الكامل

Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells حسب Mohamed Qasim Al-Fahdawi (17844209)

"…The cytotoxicity of Pt/MgO nanoparticles was determined via the 3-(4,5-dimethylthiazol-2-yl)−2,5-diphenyltetrazolium bromide assay on the human lung and colonic cancer cells (A549 and HT29 respectively) and normal human lung and colonic fibroblasts cells (MRC-5 and CCD-18Co repectively). …"

eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways حسب Zvi Cramer (10742876)

"…These effects are likely dependent on the inhibition of eIF4A activity since we observed similar results using PatA. …"

Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal حسب Zehra Irshad (18614869)

"…Human aortal endothelial cells (HAECs) were incubated in high glucose concentration (20 mM versus 5 mM control) in vitro for 3–6 days. Flux of glucose metabolism, MG formation and glycation and changes in cytosolic protein abundances, MG modification and proteotoxic responses were assessed. …"

Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection? حسب Abu Saleh Md Moin (6189512)

"…The Renin-Angiotensin System (RAS) is activated in type 2 diabetes (T2D); therefore, the aim of this study was to determine if hypoglycaemia-induced stress in T2D would potentiate serum NRP1(sNRP1) levels, reflecting an increased risk for SARS-CoV-2 infection.</p><h3>Methods</h3><p dir="ltr">A case-control study of aged-matched T2D (n = 23) and control (n = 23) subjects who underwent a hyperinsulinemic clamp over 1-hour to hypoglycemia(<40mg/dl) with subsequent timecourse of 4-hours and 24-hours. …"

Genome-Wide Association Study of Vitamin D Deficiency in the Middle East With a Relevant Characterization of the Novel <i>SDR42E1 </i>Gene حسب Nagham Nafiz Ahmad Hendi (19938204)

"…Cellular viability also decreased significantly after the knockout of SDR42E1 in the HCT116 cells.…"

Addressing Challenges of Distance Learning in the Pandemic with Edge Intelligence Enabled Multicast and Caching Solution حسب Kashif Bilal (16896357)

"…Due to the closure of educational institutes, work and learn from home methods have burdened the network resources and considerably decreased a viewer’s Quality of Experience (QoE). The situation calls for innovative techniques to handle the surging load of video traffic on cellular networks. …"

Rebound effects undermine carbon footprint reduction potential of autonomous electric vehicles حسب Nuri C. Onat (14779093)

Application of Fe₃O₄ magnetite nanoparticles grafted in silica (SiO₂) for oil recovery from oil in water emulsions حسب Wamda Faisal Elmobarak (17058024)

"…An excellent %_hdem 90% was achieved C_oil in the range 50 e2000 mg/L. Using an MD_dose as low as 10 mg/L attained a %_hdem in the range of 93% - 4.3% for O/W mixtures with C_oil < 2000 mg/L, which slightly decreased to ~90% for higher concentrations. …"

Effect of hexagonal on the in-plane crushing behaviour of plain weave composite hexagonal quadruple ring system حسب E. Mahdi (17191210)

"…Increasing the cell angle showed a decrease in energy absorption capability and load carrying capacity. …"

High-Performance Acetic Acid Sensing Using Cerium-MoS₂ Composite for Beverages and Food Processing Industry حسب E. Safamariyam (22330186)

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies حسب Fawaz E., Alanazi

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل