Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T... by Jiaxing Zhao (3965057)

“…Moreover, mouse models suggested that compound <b>20g</b> (1.5 mg/kg) could achieve roughly the same efficacy against ulcerative colitis compared with tofacitinib (10 mg/kg) and did not impair natural killer cells. …”

Post-losartan treatment prevented SARS-CoV-2 spike protein-induced decreased cognitive impairment but not pre-losartan treatment. by Mackenzi Meier (19251139)

FTY720 treatment decreased tumor growth in a xenograft model of hepatoblastoma. by Laura L. Stafman (6577184)

“…<p>(A) HuH6 cells (2.5 x 10⁶ cells in 25% Matrigel) were injected subcutaneously into the right flank of 6-week-old female athymic nude mice. …”

Top k-NN clusters of metabolites decreased at 4 hours. by Zarazuela Zolkipli-Cunningham (5234186)

Top k-NN cluster of metabolites decreased at 30 minutes. by Zarazuela Zolkipli-Cunningham (5234186)

Femur length anomalies tend to decrease with later phenology (greater day of year of adulthood anomaly) regardless of elevation or species’ seasonal timing. by César R. Nufio (11646271)

Expressions of core UPR^mt proteins following PM2.5 exposure. by Cao Wang (1500691)

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Retinoic acid alleviates decreases of phospho-Akt and phospho-Bad expression caused by MCAO damage. by Ju-Bin Kang (16021324)

(a) Changes of SOC (Soil organic matter) content during acification of black soil. The control group (0Y) received no fertilization, while the treatment groups included soils that... by Xiaoxu Zhu (11764430)

Study area in the Greater Yellowstone Ecosystem. by Taza D. Schaming (8911517)

24 hours of ARD results in noticeable decrease in ORO staining. by Moriah Eustice (13813098)

“…<p>(A) Decrease in ORO signal were observable at 24 hr after worms were placed on ARD plates (as compared to control fed worms in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0274076#pone.0274076.g005" target="_blank">Fig 5</a>), as shown with representative strains. …”

MiR-132-3p was downregulated in TGF-<i>β</i>1 stimulated Met-5A cells and miR-132-3p mimics and miR-132-3p inhibitor transfected Met-5A cells. by Yangyang Yin (14323701)

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Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

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Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

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Primary pharmacokinetic parameters of paclitaxel in rats after intravenous administration of Taxol, Abraxane, or self-made nanoparticles at a paclitaxel dose of 7mg/kg (<i>n</i> =... by Yue Gao (263086)

Results of different P forms in soil (mg kg^-1). by Wenzhi Zhao (453144)

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Multiple platforms use by working from home: Decreased alcohol use (%). by Karen G. Chartier (11714643)

Dasatinib plasma pharmacokinetics in male and female VD₃ sufficient and deficient mice after a single oral gavage of 10 mg/kg dasatinib. by Kavya Annu (11587215)

Retinoic acid alleviates decrease of phospho-Bad and 14-3-3 interaction caused by MCAO damage. by Ju-Bin Kang (16021324)

<i>Il-17c</i> deletion decreases the expression of inflammatory cytokines. by Giovanna Vella (6413774)