Table 7_A population-based analysis of the global burden of epilepsy across all age groups (1990–2021): utilizing the Global Burden of Disease 2021 data.xlsx by Ling-zhi Yang (20418434)

“…</p>Finding<p>In 2021, there were 24,220,856 (95% UI: 18,476,943–30,677,995) patients with epilepsy, with an age-standardized prevalence rate (ASPR) of 307.38 per 100,000 persons (95% UI: 234.71–389.02) and an age-standardized incidence rate (ASIR) of 42.821 per 100,000 persons (95% UI: 31.24–53.72).The global age-standardized mortality rate (ASMR) of epilepsy was 1.74 per 100,000 population (95% UI: 1.46–1.92); The age-standardized DALYs rate (ASDR) were 177.85 per 100,000 population (95% UI: 137.66–225.90); 154.25 per 100,000 population for females [114.73–201.76], and 201.29 per 100,000 population for males [157.93–252.74]. …”

Table 3_A population-based analysis of the global burden of epilepsy across all age groups (1990–2021): utilizing the Global Burden of Disease 2021 data.xlsx by Ling-zhi Yang (20418434)

“…</p>Finding<p>In 2021, there were 24,220,856 (95% UI: 18,476,943–30,677,995) patients with epilepsy, with an age-standardized prevalence rate (ASPR) of 307.38 per 100,000 persons (95% UI: 234.71–389.02) and an age-standardized incidence rate (ASIR) of 42.821 per 100,000 persons (95% UI: 31.24–53.72).The global age-standardized mortality rate (ASMR) of epilepsy was 1.74 per 100,000 population (95% UI: 1.46–1.92); The age-standardized DALYs rate (ASDR) were 177.85 per 100,000 population (95% UI: 137.66–225.90); 154.25 per 100,000 population for females [114.73–201.76], and 201.29 per 100,000 population for males [157.93–252.74]. …”

Table 8_A population-based analysis of the global burden of epilepsy across all age groups (1990–2021): utilizing the Global Burden of Disease 2021 data.xlsx by Ling-zhi Yang (20418434)

“…</p>Finding<p>In 2021, there were 24,220,856 (95% UI: 18,476,943–30,677,995) patients with epilepsy, with an age-standardized prevalence rate (ASPR) of 307.38 per 100,000 persons (95% UI: 234.71–389.02) and an age-standardized incidence rate (ASIR) of 42.821 per 100,000 persons (95% UI: 31.24–53.72).The global age-standardized mortality rate (ASMR) of epilepsy was 1.74 per 100,000 population (95% UI: 1.46–1.92); The age-standardized DALYs rate (ASDR) were 177.85 per 100,000 population (95% UI: 137.66–225.90); 154.25 per 100,000 population for females [114.73–201.76], and 201.29 per 100,000 population for males [157.93–252.74]. …”

Table 12_A population-based analysis of the global burden of epilepsy across all age groups (1990–2021): utilizing the Global Burden of Disease 2021 data.xlsx by Ling-zhi Yang (20418434)

“…</p>Finding<p>In 2021, there were 24,220,856 (95% UI: 18,476,943–30,677,995) patients with epilepsy, with an age-standardized prevalence rate (ASPR) of 307.38 per 100,000 persons (95% UI: 234.71–389.02) and an age-standardized incidence rate (ASIR) of 42.821 per 100,000 persons (95% UI: 31.24–53.72).The global age-standardized mortality rate (ASMR) of epilepsy was 1.74 per 100,000 population (95% UI: 1.46–1.92); The age-standardized DALYs rate (ASDR) were 177.85 per 100,000 population (95% UI: 137.66–225.90); 154.25 per 100,000 population for females [114.73–201.76], and 201.29 per 100,000 population for males [157.93–252.74]. …”

Table 5_A population-based analysis of the global burden of epilepsy across all age groups (1990–2021): utilizing the Global Burden of Disease 2021 data.xlsx by Ling-zhi Yang (20418434)

“…</p>Finding<p>In 2021, there were 24,220,856 (95% UI: 18,476,943–30,677,995) patients with epilepsy, with an age-standardized prevalence rate (ASPR) of 307.38 per 100,000 persons (95% UI: 234.71–389.02) and an age-standardized incidence rate (ASIR) of 42.821 per 100,000 persons (95% UI: 31.24–53.72).The global age-standardized mortality rate (ASMR) of epilepsy was 1.74 per 100,000 population (95% UI: 1.46–1.92); The age-standardized DALYs rate (ASDR) were 177.85 per 100,000 population (95% UI: 137.66–225.90); 154.25 per 100,000 population for females [114.73–201.76], and 201.29 per 100,000 population for males [157.93–252.74]. …”

Chronic hM4D_i EC DREADDs activation reduces tau pathology in downstream hippocampal subregions. by Gustavo A. Rodriguez (9268596)

“…Scale bars, 100 μm. <b><i>J</i>.</b> AT8+ immunostaining for hyperphosphorylated tau revealed decreased tau accumulation in the DG and CA1 subregions in the right hemisphere, downstream from hM4D_i EC DREADDs expression. …”

Data_Sheet_1_The global, regional, and national burden of stomach cancer among adolescents and young adults in 204 countries and territories, 1990–2019: A population-based study.ZI... by Ziqiang Zhang (7137512)

“…Compared with 1990, in 2019 more than 1,075 more incident cases of AYA stomach cancer were estimated with a decrease of 7,784 deaths. Despite the increase in absolute number of incident cases, the worldwide age-standardized rates of AYA stomach cancer (incidence, deaths, and DALYs) have declined since 1990. …”

Effect of Integrated Capacity-Building Interventions on Malaria Case Management by Health Professionals in Uganda: A Mixed Design Study with Pre/Post and Cluster Randomized Trial C... by Martin Kayitale Mbonye (507318)

“…The proportion of patients with a negative diagnostic test result for malaria prescribed an antimalarial decreased in arm B (aRR = 0.96; 99%CI: 0.84, 1.10) and arm A (aRR = 0.67; 99%CI: 0.46, 0.97); (aRRR = 0.70; 99%CI: 0.48, 1.00). …”

Table_1_Using Surveillance of Animal Bite Patients to Decipher Potential Risks of Rabies Exposure From Domestic Animals and Wildlife in Brazil.xlsx by Julio A. Benavides (4710042)

“…We analyzed one decade of bite patient data from the national health information system (SINAN) comprising over 500,000 patients attending public health facilities after being bitten by a domestic or wild animal. Our analyses show that, between 2008 and 2016, patients were mostly bitten by domestic dogs (average annual dog bite patients: 502,043 [436,391–544,564], annual incidence per state: 258 dog bites/100,000 persons) and cats (76,512 [56,588–97,580] cat bites, 41 cat bites/100,000/year), but bites from bats (4,172 [3,351–5,365] bat bites, 2.3/100,000/year), primates (3,320 [3,013–3,710] primate bites, 2.0/100,000/year), herbivores (1,908 [1,492–2,298] herbivore bites, 0.9/100,000/year) and foxes (883 [609–1,086] fox bites, 0.6/100,000/year) were also considerable. …”

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of High-Dose Rebamipide Treatment for Low-Dose Aspirin-Induced Moderate-to-Severe Small Intestinal Damage by Toshio Watanabe (151136)

“…</p><p>Aim</p><p>We conducted a multicenter, randomized, double-blind, placebo-controlled trial to assess the efficacy of a high dose of rebamipide, a gastroprotective drug, for LDA-induced moderate-to-severe enteropathy.…”

Table_1_Associations among past trauma, post-displacement stressors, and mental health outcomes in Rohingya refugees in Bangladesh: A secondary cross-sectional analysis.pdf by Haley Ritsema (14431125)

“…Trauma (OR = 4.98, 95% CI = 2.20–11.31, p < 0.001) was associated with increased odds of PTSD. Living in a household that received income was associated with decreased odds of PTSD (OR = 0.74, 95% CI = 0.55–1.00, p = 0.05).…”

Table_1_Effectiveness of sofosbuvir-based treatments for patients with hepatitis C virus genotype 6 infection: a real-world study from East China.DOC by Fan-Rong Jiang (20325720)

“…In PP population, the end of treatment virological response rate was 99.48% (190/191), the SVR12 rate was 99.31% (143/144), and the SVR24 rate was 100.00% (75/75). Only one patient with genotype 6a experienced a relapse 12 weeks after the completion of treatment, but her HCV RNA was undetectable both at the end of treatment and 24 weeks after the end of treatment. …”

Data Sheet 1_Impact of mini-dose dexmedetomidine supplemented analgesia on sleep structure in patients at high risk of obstructive sleep apnea: a pilot trial.docx by Pei Sun (115160)

“…</p>Setting<p>A tertiary university hospital in Beijing, China.…”

Scribble regulates myelin thickness and ERK activation in oligodendrocytes. by Andrew A. Jarjour (343100)

“…<p>A,B,D,E; At P40, decreased myelination of small-diameter axons in both optic nerve (B) and spinal cord (E) of Scribble cKO mice persists relative to wild-type littermates (A,D). …”

Table_1_Effect of Late Testing and Antiretroviral Treatment on Mortality Among People Living With HIV in the Era of Treat-All in Guangdong Province, China, 1992–2018: A Cohort Stud... by Qiaosen Chen (9324631)

“…The all-cause mortality saw a decreasing trend from 1.46 cases/100 person-year in January 2009 to 0.14 cases/100 person-year in December 2018 (standardized rate). …”

Deletion of <i>Rps6</i> in adult liver induces hepatocyte apoptosis and triggers regeneration. by Sarah A. Comerford (3854917)

“…Scale bars: a), c) and d), 100μ; b) and e), 50μ. (F) Photomicrographs of IHC for PCNA, phospho-RPS6^(Ser235/6) and pan-cytokeratin (CK) on livers of ΔS6^dox mice provided with dox for 54 days showing that regenerating nodules contain PCNA- and phospho-RPS6^(Ser235/6)-positive immature hepatocytes while pan-CK-positive cells comprise the dr. …”

Table1_In vitro effects of European and Latin-American medicinal plants in CYP3A4 gene expression, glutathione levels, and P-glycoprotein activity.DOCX by Andre Luis Dias Araujo Mazzari (13907910)

“…In this study, we assess non-toxic concentrations (up to100 μg/ml) of their infusions for in vitro ability to modulate CYP3A4 mRNA gene expression and intracellular glutathione levels in HepG2 cells, as well as P-glycoprotein (P-gp) activity in vincristine-resistant Caco-2 cells (Caco-2 VCR). …”

FLIM imaging of live mouse intestinal organoids stained with HXT (1.5 μM, 4 h) and BrdU. by Irina A. Okkelman (3544946)

“…(<b>e</b>) FLIM image of an individual crypt from organoid incubated with BrdU (100 μM, 4 h) shows fewer nuclei with decreased τ_m. …”

Data_Sheet_1_Dynamic Changes of Metabolic Syndrome Alter the Risks of Cardiovascular Diseases and All-Cause Mortality: Evidence From a Prospective Cohort Study.docx by Di He (791903)

Data_Sheet_1_Enrichment and Aggregation of Purple Non-sulfur Bacteria in a Mixed-Culture Sequencing-Batch Photobioreactor for Biological Nutrient Removal From Wastewater.pdf by Marta Cerruti (1385694)

“…Acetate, ammonium, and orthophosphate were removed up to 96% at a rate of 1.1 kg COD d^–1 m^–3, 77% at 113 g N d^–1 m^–3, and 73% at 15 g P d^–1 m^–3, respectively, with COD:N:P assimilation ratio of 100:6.7:0.9 m/m/m. …”