Pre-administration of metformin 3 days before irradiation significantly decreases the number of micronuclei in murine bone marrow cells and the number of DNA damage foci in colon a... by Silvia Siteni (10344070)

“…<p>(A) Metformin 200 mg/kg pre-administration significantly decreases the number of micronuclei in mice bone marrow cells, compared to the 7.5 cGy control, in 129/sv mice one-way ANOVA, **p<0.01, ****p<0.0001). …”

The expression of genes related to mitochondria was decreased in Pgam2 mice. by Junji Okuda (444322)

“…NRF-1: nuclear respiratory factor 1; CD36/FAT: CD36/fatty acid translocase; MCAD: medium-chain acyl coenzyme A dehydrogenase; Cox5a: mitochondrial cytochrome c oxidase subunit Va. …”

Overexpression of TRIM2 decreases Junín virus but not OWA infection. by Nicolas Sarute (6307643)

Decreased neutrophil-mediated pathology in the liver of co-infected mice. by Kristen L. Lokken (558435)

Loss of FOXP1 results in decreased number of bRGCs. by Seon Hye E. Park (16765033)

Decreased ETPs in mTORC1/Raptor-deficient thymi. by Hong-Xia Wang (288934)

Cell proliferation is significantly decreased by age in the mouse hippocampal DG. by Joana Gil-Mohapel (462002)

Neuronal differentiation is significantly decreased by age in the mouse hippocampal DG. by Joana Gil-Mohapel (462002)

Cellular viability decreases in breast cancer cells treated with clotrimazole. by Cristiane M. Furtado (333360)

Introduction of the F region decreases the amount of extracellular PSMs and increases the amount of extracellular FnbA. by Chikara Kaito (230958)

Glutamate excitotoxicity decreases GAD65/67 mRNA. by Márcio S. Baptista (365618)

Target specificity, <i>in vivo</i> pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma by Peter Y. Yu (4281448)

“…The purpose of this work was to develop and test a novel putative STAT3 inhibitor, LY5.</p><p>Methods and findings</p><p>An <i>in silico</i> fragment-based drug design strategy was used to create LY5, a small molecule inhibitor that blocks the STAT3 SH2 domain phosphotyrosine binding site, inhibiting homodimerization. …”

Overexpression of Jagn1 decreases steady-state insulin levels. by Courtney Nosak (1807867)

h-GAAP Decreases Cell Susceptibility to Extrinsic Apoptosis Pathways by Caroline Gubser (24818)

PTB is associated with decreased antigen-stimulated production of IL-4. by Nathella Pavan Kumar (129299)

Reverse activation tendency decreases for spikes occurring later in SWRs by Jozsef Csicsvari (82625)

Stable knockdown of JTB in HCC cells decreases cell apoptosis. by Yun-Peng Liu (108506)

Decreased HbNO production in HbE/ß-thal subjects. by Attaphon Chamchoi (5774669)

Decreased TORC1 activates HPK-1 to extend longevity. by Ritika Das (4514968)

Intrahepatic CXCL9 expression decreases significantly after hepatectomy. by Takuya Yano (415157)