DataSheet_2_Isoliquiritigenin Derivative Regulates miR-374a/BAX Axis to Suppress Triple-Negative Breast Cancer Tumorigenesis and Development.pdf by Fu Peng (1426402)

“…Recent studies suggest that isoliquiritigenin (ISL) can significantly suppress the growth, migration, and invasion of breast cancer cells. We previously synthesized ISL derivatives and found that 3′,4′,5′,4″-tetramethoxychalcone (TMC) inhibits TNBC cell proliferation to a greater degree than ISL. …”

DataSheet_1_Isoliquiritigenin Derivative Regulates miR-374a/BAX Axis to Suppress Triple-Negative Breast Cancer Tumorigenesis and Development.zip by Fu Peng (1426402)

“…Recent studies suggest that isoliquiritigenin (ISL) can significantly suppress the growth, migration, and invasion of breast cancer cells. We previously synthesized ISL derivatives and found that 3′,4′,5′,4″-tetramethoxychalcone (TMC) inhibits TNBC cell proliferation to a greater degree than ISL. …”

Novel model for the manipulation of host responses by <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> (MAP) for its survival during subclinical stages of Johne’s disease.... by Hyun-Eui Park (4047733)

“…<p>MAP can manipulate host responses to enhance its survival. Upregulation of PIP5K1C and downregulation of IL-17A, IL-17F, and IL-26 induces a loss of granuloma integrity, which can result in fecal shedding and dissemination of MAP. …”

Forest plot of reported treatment effect* of pregabalin by 5-year interval and overall. by Emma T. L. Cheng (14486376)

Daily and annual total global rainfall in Gt/day estimated from the ERA5 reanalysis. by Rasmus E. Benestad (12530330)

Effect of deferiprone in HIV-infected primary cells: Apoptotic DNA fragmentation, deoxyhypusyl-eIF5A accumulation, and DOHH activity. by Deepti Saxena (462177)

The timeline of the experiment. by Shadi Nazarizadeh (20108029)

“…This study focuses on examining the effects of dimethyl itaconate (DMI) on cognition, motor coordination, and anxiety-like behavior in male rats that have experienced HINS. 42 male Wistar newborn rats (PND10) were randomly divided into six groups (n = 7). 1) Control (Vehicle only); received DMI solvent (0.1ml) without applying hypoxia. 2–3) DMI; receiving (20 and 50 mg/kg; i.p). 4) HINS; they were placed in a hypoxia chamber with 7% oxygen and 93% nitrogen concentration for 15 minutes. 5–6) DMI+HINS; received DMI (20 and 50 mg/kg; i.p) 24h before hypoxia. …”

S1 Raw data - by Shadi Nazarizadeh (20108029)

“…This study focuses on examining the effects of dimethyl itaconate (DMI) on cognition, motor coordination, and anxiety-like behavior in male rats that have experienced HINS. 42 male Wistar newborn rats (PND10) were randomly divided into six groups (n = 7). 1) Control (Vehicle only); received DMI solvent (0.1ml) without applying hypoxia. 2–3) DMI; receiving (20 and 50 mg/kg; i.p). 4) HINS; they were placed in a hypoxia chamber with 7% oxygen and 93% nitrogen concentration for 15 minutes. 5–6) DMI+HINS; received DMI (20 and 50 mg/kg; i.p) 24h before hypoxia. …”

S1 Graphical abstract - by Shadi Nazarizadeh (20108029)

“…This study focuses on examining the effects of dimethyl itaconate (DMI) on cognition, motor coordination, and anxiety-like behavior in male rats that have experienced HINS. 42 male Wistar newborn rats (PND10) were randomly divided into six groups (n = 7). 1) Control (Vehicle only); received DMI solvent (0.1ml) without applying hypoxia. 2–3) DMI; receiving (20 and 50 mg/kg; i.p). 4) HINS; they were placed in a hypoxia chamber with 7% oxygen and 93% nitrogen concentration for 15 minutes. 5–6) DMI+HINS; received DMI (20 and 50 mg/kg; i.p) 24h before hypoxia. …”

Means and Cronbach’s alphas for 5C and VAX-measured vaccination attitudes over 12 months. by Allyson J. Gallant (9382396)

Image3_miR-146a is a critical target associated with multiple biological pathways of skin aging.jpg by Klodjan Stafa (154945)

“…Effects on markers of skin aging, including cell proliferation, production of Collagen-1 and inflammatory cytokines were assessed.</p><p>Results: We show that the expression of miR-146a decreases with age in dermal fibroblasts and inhibition of miR-146a in 19y and 62y old NHDFs induced significant changes in essential clock genes indicating an association with circadian rhythm control. …”

Image1_miR-146a is a critical target associated with multiple biological pathways of skin aging.jpg by Klodjan Stafa (154945)

“…Effects on markers of skin aging, including cell proliferation, production of Collagen-1 and inflammatory cytokines were assessed.</p><p>Results: We show that the expression of miR-146a decreases with age in dermal fibroblasts and inhibition of miR-146a in 19y and 62y old NHDFs induced significant changes in essential clock genes indicating an association with circadian rhythm control. …”

Image2_miR-146a is a critical target associated with multiple biological pathways of skin aging.jpg by Klodjan Stafa (154945)

“…Effects on markers of skin aging, including cell proliferation, production of Collagen-1 and inflammatory cytokines were assessed.</p><p>Results: We show that the expression of miR-146a decreases with age in dermal fibroblasts and inhibition of miR-146a in 19y and 62y old NHDFs induced significant changes in essential clock genes indicating an association with circadian rhythm control. …”

Effect of different polyunsaturated fatty acids (PUFAs) in the inhibition of HCoV-229Eviral replication in MRC5 cells using antibody-based assay demonstrates significant inhibition... by Amanda Watson (4447267)

Low complexity sequences are involved in binding between AR and KDM4A. by Carlos M. Roggero (11909585)

Longer polyQ sequences increase the tendency of AR-NTD to form gels. by Carlos M. Roggero (11909585)

DataSheet_1_Bortezomib Inhibits Multiple Myeloma Cells by Transactivating ATF3 to Trigger miR-135a-5p- Dependent Apoptosis.docx by Xiaolan Lai (11464909)

“…This was accompanied by low levels of Noxa, CHOP, and DR5, and a decrease in mitochondrial membrane potential. …”

S5 Table - by Amábilli de Souza Rosar (20536911)

S5 Dataset - by Shinichi Chisada (15354141)

Gaussian model fitted of the number of dogs detections of SARS-CoV-2, depending on the cycle threshold (Ct) values of RT-qPCR tests for SARS-CoV-2. by Víctor M. Vidal-Martínez (18707335)