Loss of <i>bmm</i> function in the somatic cells of the gonad with an independent GAL4 line affects whole-body triglyceride breakdown in males but not females. by Lianna W. Wat (8339454)

“…(C) Between 0 and 12 hours STV, the magnitude of triglyceride breakdown in <i>tj>UAS-bmm-RNAi</i> was similar to <i>tj>+</i> and <i>+>UAS-bmm-RNAi</i> control males; however, between 12 and 24 hours STV, there was no significant decrease in triglyceride levels in <i>tj>UAS-bmm-RNAi</i> males, in contrast to <i>tj>+</i> and <i>+>UAS-bmm-RNAi</i> control males, in which we observed a significant decrease in triglyceride storage STV (<i>p</i> = 9.7 × 10⁻⁴, 0.0018, and 0.099 for 0–12 hours and 0.37, 1.9 × 10⁻⁵, and 0.028 for 12–24 hours, respectively; one-way ANOVA followed by Tukey HSD test). …”

Pairwise variant allele frequency (VAF) histograms for virtual primary tumors. by Ruping Sun (10319284)

“…Note the increasing number of public variants and decreasing Fst on the lower panel (<i>s</i> = 0.2 and <i>s</i> = 0.5).…”

Fig 1 - by Manabu Murakami (1786186)

“…Representative immunoblots of membranes from wild-type and transgenic mice analyzed for the expression of CaV1.2 (α1C) and GAPDH. A significant decrease in the Cav1.2 protein level was observed. n = 6. …”

Image_1_Assessment of Epigenetic and Phenotypic Variation in Populus nigra Regenerated via Sequential Regeneration.tif by Weixi Zhang (1626823)

“…We detected a significant difference in methylation levels between first regeneration regenerated plants (G1) and those of the other four generations (G2–G5); there were no significant differences among the four later generations. …”

microRNA-14 as an efficient suppressor to switch off ecdysone production after ecdysis in insects by Kang He (189002)

“…In summary, we present evidence that a pre-miRNA encodes two mature miRNAs targeting on the same pathway, which significantly improves miRNA regulation efficiencies to programmatically switch off ecdysone biosynthesis.…”

LUSK_CIG_2020.pdf by Alexander Lusk (9143845)

Expectation adaptation during natural reading by Shaorong Yan (6530024)

Conditional disruption of the <i>P</i>. <i>falciparum RAMA</i> gene. by Emma S. Sherling (7354880)

“…<p>(A) The <i>RAMA</i> gene (PlasmoDB PF3D7_0707300) comprises 5 exons (numbered grey boxes; not to scale) and 4 introns (blue lines). …”

DataSheet_1_Borealin/CDCA8 deficiency alters thyroid development and results in papillary tumor-like structures.pdf by Hortense Didier-Mathon (17294674)

“…</p>Results<p>Thyroid development was impaired with a hyperplastic anlage on embryonic day E9.5 followed by thyroid hypoplasia from E11.5 onward. …”

Data_Sheet_1_SWL-1 Reverses Fluconazole Resistance in Candida albicans by Regulating the Glycolytic Pathway.doc by Xiao-Ning Li (2008540)

“…In this study, we show that SWL-1 reverses resistance to fluconazole in C. albicans when delivered in combination, with a sharp decrease in the IC₅₀ of fluconazole from >200 to 3.74 ± 0.25 μg/ml, and also reverses the fluconazole resistance of C. albicans in vitro, with IC₅₀ from >200 to 5.3 ± 0.3 μg/ml. …”

Data_Sheet_1_Role of Tryptophan in Microbiota-Induced Depressive-Like Behavior: Evidence From Tryptophan Depletion Study.docx by Iva Lukić (6793748)

“…To test this hypothesis, we examined depressive-like behavior and brain levels of serotonin and tryptophan, of germ free (GF) and specific-pathogen free (SPF) mice under basal conditions, or after acute tryptophan depletion (ATD) procedure, which is a method to decrease tryptophan and serotonin levels in the brain. …”

Artificial intelligence enabled parabolic response surface platform identifies ultra-rapid near-universal TB drug treatment regimens comprising approved drugs by Daniel L. Clemens (1477516)

“…We then evaluated the efficacy in mice of optimized PRS Regimens IV and V, as well as a 3-drug regimen, PRS Regimen VI (CFZ, BDQ, and PZA), and compared their efficacy to PRS Regimen III (CFZ, BDQ, PZA, and SQ109), previously shown to reduce the time to achieve relapse-free cure in mice by 80% compared with the Standard Regimen (isoniazid, rifampicin, PZA, and ethambutol). …”

Table_7_One-carbon pathway metabolites are altered in the plasma of subjects with Down syndrome: Relation to chromosomal dosage.xlsx by Beatrice Vione (10734998)

“…Several studies demonstrated that trisomy 21 causes an alteration in the metabolic profile, involving among all the one-carbon cycle.</p>Methods<p>We performed enzyme-linked immunosorbent assays (ELISAs) to identify the concentration of 5 different intermediates of the one-carbon cycle in plasma samples obtained from a total of 164 subjects with DS compared to 54 euploid subjects. …”

Table_8_One-carbon pathway metabolites are altered in the plasma of subjects with Down syndrome: Relation to chromosomal dosage.xlsx by Beatrice Vione (10734998)

“…Several studies demonstrated that trisomy 21 causes an alteration in the metabolic profile, involving among all the one-carbon cycle.</p>Methods<p>We performed enzyme-linked immunosorbent assays (ELISAs) to identify the concentration of 5 different intermediates of the one-carbon cycle in plasma samples obtained from a total of 164 subjects with DS compared to 54 euploid subjects. …”

Table_3_One-carbon pathway metabolites are altered in the plasma of subjects with Down syndrome: Relation to chromosomal dosage.xlsx by Beatrice Vione (10734998)

“…Several studies demonstrated that trisomy 21 causes an alteration in the metabolic profile, involving among all the one-carbon cycle.</p>Methods<p>We performed enzyme-linked immunosorbent assays (ELISAs) to identify the concentration of 5 different intermediates of the one-carbon cycle in plasma samples obtained from a total of 164 subjects with DS compared to 54 euploid subjects. …”

Table_12_One-carbon pathway metabolites are altered in the plasma of subjects with Down syndrome: Relation to chromosomal dosage.xlsx by Beatrice Vione (10734998)

“…Several studies demonstrated that trisomy 21 causes an alteration in the metabolic profile, involving among all the one-carbon cycle.</p>Methods<p>We performed enzyme-linked immunosorbent assays (ELISAs) to identify the concentration of 5 different intermediates of the one-carbon cycle in plasma samples obtained from a total of 164 subjects with DS compared to 54 euploid subjects. …”

Table_3_One-carbon pathway metabolites are altered in the plasma of subjects with Down syndrome: Relation to chromosomal dosage.xlsx by Beatrice Vione (10734998)

“…Several studies demonstrated that trisomy 21 causes an alteration in the metabolic profile, involving among all the one-carbon cycle.</p>Methods<p>We performed enzyme-linked immunosorbent assays (ELISAs) to identify the concentration of 5 different intermediates of the one-carbon cycle in plasma samples obtained from a total of 164 subjects with DS compared to 54 euploid subjects. …”

Table_13_One-carbon pathway metabolites are altered in the plasma of subjects with Down syndrome: Relation to chromosomal dosage.xlsx by Beatrice Vione (10734998)

“…Several studies demonstrated that trisomy 21 causes an alteration in the metabolic profile, involving among all the one-carbon cycle.</p>Methods<p>We performed enzyme-linked immunosorbent assays (ELISAs) to identify the concentration of 5 different intermediates of the one-carbon cycle in plasma samples obtained from a total of 164 subjects with DS compared to 54 euploid subjects. …”

Data_Sheet_1_One-carbon pathway metabolites are altered in the plasma of subjects with Down syndrome: Relation to chromosomal dosage.xlsx by Beatrice Vione (10734998)

“…Several studies demonstrated that trisomy 21 causes an alteration in the metabolic profile, involving among all the one-carbon cycle.</p>Methods<p>We performed enzyme-linked immunosorbent assays (ELISAs) to identify the concentration of 5 different intermediates of the one-carbon cycle in plasma samples obtained from a total of 164 subjects with DS compared to 54 euploid subjects. …”

Table_13_One-carbon pathway metabolites are altered in the plasma of subjects with Down syndrome: Relation to chromosomal dosage.xlsx by Beatrice Vione (10734998)

“…Several studies demonstrated that trisomy 21 causes an alteration in the metabolic profile, involving among all the one-carbon cycle.</p>Methods<p>We performed enzyme-linked immunosorbent assays (ELISAs) to identify the concentration of 5 different intermediates of the one-carbon cycle in plasma samples obtained from a total of 164 subjects with DS compared to 54 euploid subjects. …”