Pyrimidine synthesis and transport is very sensitive to mis-regulation. by Indu Warrier (581139)

“…<b>(E)</b> Adding additional uracil to the medium (from 20 ug/mL to 100 ug/mL) does not alter the uracil independent growth defect observed for SP_0701_mOFF (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011188#pgen.1011188.s003" target="_blank">S3 Table</a>). …”

Image_1_Effects of 1,25-Dihydroxyvitamin D3 and 25-Hydroxyvitamin D3 on PBMCs From Dairy Cattle Naturally Infected With Mycobacterium avium subsp. paratuberculosis.pdf by Taylor L. T. Wherry (10022300)

“…Briefly, PBMCs were isolated and cultured in vitro with 4 ng/ml 1,25-dihydroxyvitamin D₃ [1,25(OH)₂D₃] or 100 ng/ml 25(OH)D₃. Treatment with 1,25(OH)₂D₃ resulted in decreased secretion for some pro-inflammatory cytokines in clinical animals, including IL-1β, IL-6, and IFN-γ. …”

Data_Sheet_1_Effects of 1,25-Dihydroxyvitamin D3 and 25-Hydroxyvitamin D3 on PBMCs From Dairy Cattle Naturally Infected With Mycobacterium avium subsp. paratuberculosis.xlsx by Taylor L. T. Wherry (10022300)

“…Briefly, PBMCs were isolated and cultured in vitro with 4 ng/ml 1,25-dihydroxyvitamin D₃ [1,25(OH)₂D₃] or 100 ng/ml 25(OH)D₃. Treatment with 1,25(OH)₂D₃ resulted in decreased secretion for some pro-inflammatory cytokines in clinical animals, including IL-1β, IL-6, and IFN-γ. …”

Table_2_Analysis on alteration of road traffic casualties in western China from multi-department data in recent decade.XLSX by Jinlong Qiu (9159113)

“…</p>Results<p>The number of traffic accidents and fatalities decreased in low-altitude areas in western China. However, there was a significant increasing trend in the high altitude area. …”

Table_1_Analysis on alteration of road traffic casualties in western China from multi-department data in recent decade.xlsx by Jinlong Qiu (9159113)

“…</p>Results<p>The number of traffic accidents and fatalities decreased in low-altitude areas in western China. However, there was a significant increasing trend in the high altitude area. …”

<b>Dielectric Properties of Composite PZT Films with Distinct Phase Transition Temperatures via Aerosol Deposition</b> by Ye-Ji Son (20656475)

“…An enlarged section from 2θ = 20 to 80° is shown in <b>Figure 1(b)</b>, which shows the high-intensity peaks for each composition correspond to specific crystallographic planes labeled in the XRD patterns, such as (100), (110), (111), and (200). This indicates that all samples maintain a consistent perovskite structure with slight shifts in peak positions due to the differences in Zr/Ti ratios.…”

Intermittent fasting enhances long-term memory consolidation, adult hippocampal neurogenesis and expression of longevity gene Klotho (Microarray dataset) by Sandrine Thuret (10326662)

Knock out VGLL4 in valvar endothelial cells leads to hypertrophy and compromised heart function on later stage. by Wei Yu (43094)

“…<p>(A) Gross front view of hearts from 9-month-old <i>Tie2</i>^<i>Cre+</i><i>;Vgll4</i>^<i>fl/-</i> and <i>Vgll4</i>^<i>fl/-</i> control hearts. …”

Loss of <i>Smndc1</i> poison exon alters global transcript and protein abundance, while steady state RNA splicing is modestly affected. by Andrea E. Belleville (19434726)

“…<p><b>A</b>, Quantification of RNA-sequencing (RNA-seq) reads supporting <i>Smndc1</i> poison exon (PE) inclusion. …”

Inducible epidermis-specific deletion of <i>Lss</i> caused alopecia that was spontaneously and partially reversed in the mice. by Yoichi Wada (8496315)

“…<p><b>a</b>, Gross appearance of the <i>Lss</i>^<i>f/f</i><i>-K14ERT</i> or <i>Lss</i>^<i>f/f</i> mice pre- and postadministration of intraperitoneal tamoxifen. …”

<i>B. bassiana</i>-induced cell loss requires Wek, but Wek has pleiotropic functions. by Deepanshu N. D. Singh (20721878)

“…Asterisks on graphs: * <i>p</i> < 0.05, **<i>p</i> < 0.01, ***<i>p</i> < 0.001, ****<i>p</i> < 0.0001. Scale bars: (A, D, F) 100 μm. Genotypes: Control: <i>MyD88 GAL4 hisYFP/ + tubGAL80</i>^<i>ts</i><i>/ +</i> flies, whereby the GAL4 driver line was outcrossed to wild-type. …”

Extraction time and mustard concentration for extraction of aquatic oligochaetes by using wet funnel by Satoshi Kaneda (571209)

“…After 5 h of extraction, the residue was moved into the plastic tray, and the remaining individuals in the residue were counted by hand-sorting. In Exp. S1.2, a fresh volume of approximately 100 cc of stock soil which had been collected from the same station was used because the original stock soil sample had already been depleted at that point. …”

MyoF regulates the intracellular abundance of HTLV-1 Env. by Nicholas Polakowski (6894452)

“…<p><b>(A)</b> Inhibition of MyoF reduces levels of SU (gp46). …”

SEAwise report on Carbon footprint, economic and social impacts of revised management strategies by Isabella Bitetto (20145735)

“…</p><p dir="ltr">The <b>Celtic Sea case study in the Western Waters </b>showed less impact of climate change than management scenario, as some stocks were expected to increase productivity while others decreased productivity. The F_MSY-min and F_MSY-range scenarios resulted in strong reductions of fishing effort for both the LSF and the SSF, and consequently a decline in employment. …”

Inhibition of the NF-κB signaling pathway in adipocytes ameliorates survival of <i>PGRP-LB</i>^<i>Δ</i> mutant flies infected with <i>E</i>. <i>cc</i>. by Bernard Charroux (201413)

“…Flies of the following genotypes were used: <i>w</i>^<i>1118</i>/<i>w</i>^<i>1118</i>; <i>+/+</i> or <i>Mex</i>^<i>Gal4</i><i>/+</i> or <i>cg</i>^<i>Gal4</i><i>/+; PGRP-LB</i>^<i>Δ</i>, <i>Dipt-Cherry</i>^<i>C1</i>/<i>PGRP-LB</i>^<i>Δ</i>, <i>UAS-dFadd</i>^<i>IR</i> (C-D) and <i>w</i>^<i>1118</i>/<i>w</i>^<i>1118</i>;; <i>PGRP-LB</i>^<i>Δ</i>, <i>da</i>^<i>Gal4</i> or <i>PGRP-LB</i>^<i>Δ</i>, <i>Mef2</i>^{<i>Gal4</i> or} <i>PGRP-LB</i>^<i>Δ</i>, <i>r4</i>^<i>Gal4</i>/<i>PGRP-LB</i>^<i>Δ</i>, <i>UAS-dFadd</i>^<i>IR</i> (D). Scale bar is 100 μm (midguts in C) and 20 μm (fat bodies in A and C).…”

Pericardial Cyst by Christopher Komanapalli (13912363)

“…One literature review reported that one third of patients had recurrence after percutaneous drainage at three years. Injection of a sclerosing agent such as alcohol decreases the likelihood of cyst recurrence.…”

Additional data for optogenetic activation of dFB^VGlutՈ84C10 and dFB^ChATՈ84C10 neurons. by Joseph D. Jones (13883524)

“…<b>(C)</b> Box plots of nighttime sleep change in % ((nighttime sleep on activation day-nighttime sleep on baseline day/nighttime sleep on baseline day) × 100) for control (<i>Empty-Split>CsChrimson</i>), <i>VGlut-AD; 84C10-DBD>CsChrimson</i> and <i>84C10-AD; ChAT-DBD>CsChrimson</i> female flies presented in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003014#pbio.3003014.g004" target="_blank">Fig 4H</a>–<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003014#pbio.3003014.g004" target="_blank">K</a>. …”

Update on trimethylamine N-oxide (TMAO) as a piezolyte and cryoprotectant: its role in a depth limit for marine fishes and loss from hadal fish during capture by Paul Yancey (14354982)

“…Except for teleosts (see below), these animals are osmoconformers, such that as TMAO increases with depth, other osmolytes must decrease (e.g., urea in elasmobranchs as noted above). …”