Image_3_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image_4_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image_2_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image_1_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Apoptosis inhibitor prevented the decrease of IIL ESP-induced TJs expression and alleviated barrier disruption of Caco-2 monolayer. by Qi Qi Lu (17721401)

Subjects:

(A) Side image of epoxy resin-made abutment-analog base and prosthesis; (B) Front image of epoxy resin-made abutment-analog base and prosthesis. by Long Li (6555)

Subjects:

Table_1_Effects of Early Changes in Blood Pressure During Intravenous Thrombolysis on the Prognosis of Acute Ischemic Stroke Patients.docx by Zhong-Xiu Wang (9729359)

“…Patients with a lower baseline National Institute of Health Stroke Scale (NIHSS) score (8.25 ± 5.57 vs. 13.51 ± 7.42, P < 0.001), a higher Alberta Stroke Program Early CT Score (ASPECTS; 8.65 ± 1.82 vs. 8.13 ± 2.00, P = 0.005), decreased BP during thrombolysis (69.4% vs. 59.8%, P = 0.037), and steady BP (SD < 10 mmHg) were more likely to have a favorable outcome (73.9% vs. 60.6%, P = 0.019). …”

Image_1_miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4.tif by Wan Fu (3681799)

“…This study aimed to investigate the action mechanism of miR-144-5p and miR-451a in cholangiocarcinoma. We found that miR-144-5p and miR-451a were significantly decreased in cholangiocarcinoma patient samples compared to the adjacent normal bile duct samples. …”

Image_4_miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4.tif by Wan Fu (3681799)

“…This study aimed to investigate the action mechanism of miR-144-5p and miR-451a in cholangiocarcinoma. We found that miR-144-5p and miR-451a were significantly decreased in cholangiocarcinoma patient samples compared to the adjacent normal bile duct samples. …”

Image_3_miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4.tif by Wan Fu (3681799)

“…This study aimed to investigate the action mechanism of miR-144-5p and miR-451a in cholangiocarcinoma. We found that miR-144-5p and miR-451a were significantly decreased in cholangiocarcinoma patient samples compared to the adjacent normal bile duct samples. …”

Image_2_miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4.tif by Wan Fu (3681799)

“…This study aimed to investigate the action mechanism of miR-144-5p and miR-451a in cholangiocarcinoma. We found that miR-144-5p and miR-451a were significantly decreased in cholangiocarcinoma patient samples compared to the adjacent normal bile duct samples. …”

Stabilization of Hif-1α at early stages of infection leads to a decrease in bacterial burden. by Philip M. Elks (324793)

“…<p>(A) Quantification of bacterial burden by fluorescent pixel count after DMOG treatment between 5 and 6 dpi. …”

A chronic high glucose treatment decreases proteasome activities and increases apoptosis in human islets. by Christophe Broca (538652)

Topical application of ATX inhibitor (S32826) decreases IOP in rabbits. by Padma Iyer (141117)

“…A. 10 mM S32826 exhibited the maximum and statistically significant effect in lowering IOP (by 5–6 mm Hg; n = 9) with drug application at 0 and 5 hrs (indicated with arrows, 35 µl×2) relative to sham controls receiving pH adjusted water. …”

The effects of NAC on the decreased number of myotube formations caused by arecoline. by Yi-Xuan Li (6633845)

Decrease in optical density of <i>gerP</i> mutants in L-alanine and inosine. by Katherine A. Carr (259428)

“…a<p>Spores were incubated in 0.5 mM L-alanine and 1 mM inosine. ∼65% decrease in OD₆₀₀ represents ∼100% germination. …”

Chemically inhibiting LDHA or PDK1 decreases cell viability in Aβ resistant cells. by Jordan T. Newington (223389)

“…Similarly, 48 hr Aβ exposure significantly decreased cell viability in both PC12 (<b>C</b>) and B12 (<b>D</b>) resistant lines when cells were co-treated with 2.5 mM dichloroacetate (DCA), a chemical inhibitor of PDK1 (*P<0.01). …”

<i>Trappc9</i> deficient mice show a decrease in brain weight and size. by Zhengzheng S. Liang (9333660)

STX decreases the K_ATP channel activity. by Ana B. Ropero (12180)

Filter-extruded niosomes decrease in size upon freezing and thawing. by Rianne Bartelds (1343631)

“…In contrast, cryo-EM pictures of liposomes composed of unsaturated lipids plus cholesterol without (D) and with five freeze and thaw cycles (E) appear similar in size but the degree of multilamellarity decreases by the freezing-thawing and subsequent extrusion step.…”