Decreased fibrin deposition in hypoxic C3−/− mice. by Eileen M. Bauer (337320)

Loss of Sidt2 decreased insulin granule exocytosis. by Jialin Gao (420257)

Decreased NTAL expression after shRNA silencing. by Iva Polakovicova (621362)

TGF-β1 decreases RECK expression in fibroblasts. by Jaime Gutiérrez (401710)

Acute treatment of RAW264.7 macrophages with the cholesterol extracting agent MβCD during infection decreases <i>B</i>. <i>thailandensis</i> mediated host cell fusions. by Liam Whiteley (4487992)

Bortezomib decreases osteoclasts and improves fracture repair in mice. by Hengwei Zhang (2397610)

Metformin inhibits glutaminase activity in a dose dependent manner: from 17.5% at 10 mM up to 68% at 100 mM (A) (* p<0.05). by M. Mar Díaz-Herrero (646639)

Inactivation of Rb leads to decreased expression of MEG3 and re-expression inhibits proliferation in A549 cells. by Traci L. Kruer (3342425)

CD5-2 decreases established CCM lesions in the hindbrain of <i>Ccm2</i>^<i>ECKO</i> mice and lesions in the retina of <i>Ccm2</i>^<i>ECKO</i> mice. by Jia Li (160557)

RNF5 loss decreases PEL xenograft tumor growth and cell cycle gene expression. by Xiaojuan Li (351842)

CD148 knockdown reduces cell-cell adhesion and E-cadherin contacts accompanied by a decrease in Rac1 activity in A431 cells. by Keiko Takahashi (375228)

“…CD148 knockdown reduces the E-cadherin contact formation accompanied by a decrease in Rac1 activity.</p>…”

Lack of TLR signaling (MyD88^-/-) results in decreased levels of cytokines in the cornea. by Rose Y. Reins (2586106)

OCA alone markedly decreases and combined with Gemcitabine or Cisplatin abrogates growth of iCCA xenografts. by S. Di Matteo (6260417)

“…After 4 weeks, when the tumor size was approximately 100 mm³ (T₀) mice were treated with OCA (0.03% w/w, 30 mg/kg) alone or combined with Cisplatin (2.4 mg/Kg in 100 μl) or Gemcitabine (1.05 mg/Kg in 100 μl) for 5 additional weeks. a) Results are expressed as percent increase in tumor volume at different time points. …”

Decreased s.c. growth of CNDT 2.5 cells after systemic administration of DOPC liposome-conjugated siNRP-2. by Shaija Samuel (341436)

“…NRP-2-siRNA DOPC-treatment led to a significant decrease in tumor growth compared with cntr siRNA DOPC-treatment (264.4 mm³ vs. 751.3 mm³, respectively; *<i>p</i> = 0.01). …”

<i>btuE</i> expression results in decreased intracellular ROS. by Felipe A. Arenas (23050)

SPL treatment decreases diabetes-induced co-immunoprecipitation (co-IP) of cldn-4 and -8. by Eduardo Molina-Jijón (4020464)

“…Also, increased co-IP of cldn-8 with cldn-4 was found under diabetic condition and SPL decreased this interaction (C), densitometric analysis show that these changes were significant (D) (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0177362#pone.0177362.s005" target="_blank">S5 Fig</a>). …”

Inhibition of Hsp90 abolished VEGF-mediated eNOS phosphorylation and decreased NO production and cell viability in BAECs. by Yuanzhuo Chen (802891)

Decreased numbers of motor neurons in Tc1 and Dp(16)1Yey mice. by Sheona Watson-Scales (586942)

A New Rotane Family:  Synthesis, Structure, Conformation, and Dynamics of [3.4]-, [4.4]-, [5.4]-, and [6.4]Rotane¹ by Lutz Fitjer (2466634)

“…The structures of <b>6</b>, <b>7</b>, and <b>8</b> were determined by high-precision low-temperature X-ray analyses and by force field calculations using the search routine HUNTER in connection with MM3(92). The following special features were observed:  From <b>5</b> to <b>8</b>, the bond angles of the central ring increase while the bond angles at the spiro center of the spiroannelated cyclobutane rings decrease. …”

Down-regulation of PDCD4 attenuates the ability of resveratrol to decrease viability and invasiveness of PC-3M-MM2 cells. by Sandeep Sheth (112040)