Compounds decrease polyQ toxicity in a <i>pqe-1</i> independent manner in aged animals. by Cindy Voisine (30589)

BH3 Peptides induces a decrease in mitochondrial membrane potential but does not engage the Permeability Transition Pore. by Emelyn H. Shroff (163459)

Pretreatment of β-cells with recombinant CXCL12 improves viability and induces a decrease in PARP-1 activity. by Nevena Grdović (394542)

Complex I activity is increased in cells with elevated NQO1 levels and is decreased by rotenone. by Jiyeong Kim (433042)

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(B)</b> Bioluminescence recordings from the different conditions as depicted in <b>(A)</b>, the arrow indicates the time CO₂ was shifted from 5% to 1% (mean ± SE, <i>n</i> = 4 biological replicates per condition, AUC for 0 mM 0.34 ± 0.007, 1.59 ± 0.004 (<i>P</i> < 0.0001), 0.5 mM 1.00 ± 0.023, 2.68 ± 0.04 (<i>P</i> < 0.0001), 1 mM 1.66 ± 0.07, 3.34 ± 0.04 (<i>P</i> < 0.0001), 3 mM 2.06 ± 0.02, 2.79 ± 0.07 (<i>P</i> < 0.0001), 5 mM 2.02 ± 0.05, 2.43 ± 0.06 (<i>P</i> < 0.002), 7 mM 1.85 ± 0.01, 1.77 ± 0.02 (<i>P</i> < 0.02) two-sided Student’s <i>t</i> test). …”

Aspirin decreases expression of NFκB and β-catenin in colon cancer cells. by Satya Pathi (301408)

“…<p>Decreased p65/p50 in RKO (A) and SW480 (B) cells. Cells were treated for 48 hr with 5 or 10 mM, and whole cell, nuclear and cytosolic extracts were analyzed by western blot analysis as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0048208#s3" target="_blank">Experimental Procedures</a>. …”

DHT increases whereas orchidectomy decreases the weight and cross sectional area of hindlimb muscles. by Young-Eun Yoo (323357)

“…<b>A:</b> In WT mice, DHT increased the GN weight by 7% (212.4±8.8 mg), whereas orchidectomy decreased it by 14% (171.4±9.0 mg) compared with control WT mice (198.4±5.5 mg). …”

Overexpression of mC4 decreased membrane capacitance without altering overall excitability. by Ashley L. Comer (8299128)

SDG decreases iron-induced oxidative stress in H9c2 cells. by Stephanie Puukila (568109)

Decreased s.c. growth of CNDT 2.5 cells after systemic administration of DOPC liposome-conjugated siNRP-2. by Shaija Samuel (341436)

“…NRP-2-siRNA DOPC-treatment led to a significant decrease in tumor growth compared with cntr siRNA DOPC-treatment (264.4 mm³ vs. 751.3 mm³, respectively; *<i>p</i> = 0.01). …”

Does Mean Platelet Volume Decrease in the presence of Coronary Artery Fistula? by Isa Sincer (7234577)

“…<div><p>Abstract Background: Coronary artery fistula (CAF) is an abnormal connection that links a coronary artery to a cardiac chamber or another major blood vessel. …”

Firing rates of PNs (as maximum activity) in response to a single synchronous triangular pulse of 50 ms duration applied to both ORN groups. by Mario Pannunzi (553941)

Firing rates of ORNs (as maximum activity) in response to a single synchronous triangular pulse of 50 ms duration applied to both ORN groups. by Mario Pannunzi (553941)

Human cerebral organoids treated with VPA show a decreased size, impaired neurogenesis, and induction of senescence in NE cells. by Muriel Rhinn (406515)

Revisiting the sealed heating method–heating cells in a low volume decreases nuclear Chk1. by Andrew J. Massey (239469)

Chronic high glucose induces apoptosis and proteasome activities decrease in INS-1E cells. by Christophe Broca (538652)

Identification of Gut Microbiota Biomarker Genera Distinguishing Wild and Captive Animals (A) Top 50 discriminative genera selected by random forest classifier, ranked by mean decrease accuracy. by Lin Xu (94491)

mGluR5 receptor decreased glycinergic currents. by Zi-Yang Zhang (4988555)

“…(<b>E</b>) The inhibitory effect of CHPG on GlyR-IPSCs was not blocked by intracellularly loaded GDP-β-S (62.3 ± 6.4% of baseline at 15–20 min post-CHPG, <i>t</i>[6] = 2.782, <i>p</i> = 0.032), chelerythrine (60.9 ± 11.3% of baseline at 15–20 min post-CHPG, <i>t</i>[6] = 2.705, <i>p</i> = 0.035), or Ro-32-0432 (69.9 ± 3.2% of baseline at 15–20 min post-CHPG, <i>t</i>[5] = 8.495, <i>p</i> < 0.001). (<b>F</b>) Postsynaptic loading of U-0126 or PD98059 prevented CHPG from decreasing glycinergic responses (U-0126, 107.6 ± 10.4% of baseline at 15–20 min post-CHPG, <i>t</i>[8] = 0.997, <i>p</i> = 0.348; PD98059, 93.1 ± 5.0% of baseline at 15–20 min post-CHPG, <i>t</i>[5] = 0.883, <i>p</i> = 0.418). …”

Ionic currents of aglycoform decreased more readily during repetitive depolarization pulses than glycoform. by M. K. Hall (352643)

YTX treatment decreases tumour development in the B16F10 melanoma mouse model. by Araceli Tobío (3545306)