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Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
منشور في 2016"…Topotecan treatment caused a specific cell-cycle arrest at the S phase in addition to an increase in the percentage of cells in the preG phase. These alterations in cell cycle progression were further enhanced upon andrographolide pre-treatment: the percentage of cells in the S-phase reached 40.4%, compared to 19.3% upon treatment with topotecan alone. …"
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Assessment of treatment burden and its impact on quality of life in dialysis-dependent and pre-dialysis chronic kidney disease patients
منشور في 2021"…</p><h3>Results</h3><p dir="ltr">Two hundred-eighty CKD patients (HD = 223 and pre-dialysis = 57) were included in the analyses (response rate 60.9%). …"
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…"
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