Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Hematoxylin and eosin staining and Sirius red staining were performed to identify bone formation in vivo. Results. Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

“…These findings demonstrate for the first time that VISTA is suppressed by metformin and identified a new regulatory mechanism through AHR. The data suggest that metformin could be a new potential therapeutic strategy to treat melanoma patients combined with targeted immune checkpoint inhibitors.…”
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Pilot testing of a novel Multi Effect Distillation (MED) technology for seawater desalination by Shahzada Aly (17191465)

“…An advanced modular MED pilot plant has been installed with a nominal capacity of 25 m3/day to validate the concept under a seawater salinity of 57,500 ppm (Dukhan Coast, West of Qatar), at the top brine temperature of 65 °C. …”

A new perspective on cardiovascular drift during prolonged exercise by Amine Souissi (9931616)

A new quadratic asymmetric error correction model: does size matter? by Ayman Mnasri (16932486)

“…<p dir="ltr">We introduce a new quadratic asymmetric error correction model that comprehensively accounts for both sign and size asymmetries. …”

Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex by Wesam S. Ahmed (10170053)

“…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…”

Stability and thermophysical properties test of carbide-derived carbon thermal fluid; a comparison between functionalized and emulsified suspensions by Ismail W. Almanassra (14151321)

Underrepresentation of racial and ethnic minorities in cascade testing for hereditary cancer syndromes by Muhammad Danyal Ahsan (14488278)

“…Cascade testing is critical as relatives found to carry a pathogenic gene variant have the opportunity to pursue targeted cancer risk reduction and early detection, decreasing cancer-associated morbidity and mortality. …”

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i... by Samar, Shurbaji

“…AimWe aim to evaluate the performance of a new fluorescence-based LFIA and its Finecare™ fluorescent reader for quantitative measurement of TSH from a fingerstick, venepuncture whole-blood, and serum. …”
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Analysis of the resilience of the Turkey tourism industry to exogenous shocks: new evidence from a NARDL model by Lanouar Charfeddine (10705000)

Nickel toxicology testing in alternative specimen from farm ruminants in a urban polluted environment by Zafar Iqbal Khan (21225059)

Corrosion Evaluation of 316L Stainless Steel Exposed to CNT-Water Nanofluid by Dana Abdeen (18147583)

“…Adsorption isotherm for CNTs adsorption on the surface of the metal and some thermodynamic properties of adsorption were found to help in proposing a mechanism for CNTs corrosion inhibition. It was observed that the SS tested in CNTs nanofluids presented low corrosion rates, which were comparable to those for tap water and lower than those for 3.5 wt.% NaCl solutions. …”

Evaluating the Successful Initiation of a New Dialysate Potassium Management Protocol: “Reduced Emergency Department Admission with Hyperkalemia in Hamad General Hospital Dialysis... by Shajahan Joseph K (18472465)

“…</p><h3>Results</h3><p dir="ltr">ED admission of dialysis patients with hyperkalemia which require dialysis reduced from 12% to 0% (Figure 1) and the number of patients who are using low potassium bath of 1.0 mmol/L in Dialysate solution decreased from 56 in Jan 2022 to 7 patients in June 2023 (Figure 2)</p><h3>Conclusion </h3><p dir="ltr">The new potassium protocol was found to be very effective, and has a direct impact on the quality and safety of HD patients. …”

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
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Accelerating Care: Enhancing Patient Satisfaction through a Quality Initiative in the Obstetrics and Gynaecology Emergency Department at Al Wakra Hospital, Qatar by Lolwa Al Ansari (18466227)

“…The proportion of patients spending less than 8 hours in the OB ED observation beds rose from 74% in January 2022 to over 98% in 2023. Notably, there was a remarkable decrease in patients who Left Without Being Seen (LWBS) and in absconded patient rates from 2020 to 2023 (Figure 2).…”

A new method for broad‐scale modeling and projection of plant assemblages under climatic, biotic, and environmental cofiltering by Alessandro Ferrarini (3951098)

Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers by Yadav, Santosh K.

“…Significantly changed FA and MD values in different brain regions in HIC and HUC compared to CHNM were used for correlation analysis with NP test scores using Pearson’s correlation. ResultsHIC and HUC groups showed significantly decreased NP test scores in various domain compared to CHNM. …”
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Geomorphological changes in the coastal area of Farasan Al-Kabir Island (Saudi Arabia) since mid Holocene based on a multi-proxy approach by Pavlopoulos, Kosmas

“…The geomorphological evolution of the southeastern coastal area of Farasan Al-Kabir Island (Saudi Arabia) is revealed by the mapping of modern landforms and a multi-proxy and high spatial resolution study including grain size, particulate organic carbon, mineralogy, element geochemistry, benthic foraminifera analysis and radiocarbon dating of a 3.3-m long sediment core. …”
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Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders by Jaunetta Hill (18255631)