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Decreased phosphodiesterase activities in cardiac hypertrophy
منشور في 2007"…Increased heart weight (43%) in the H group was accompanied by a general decrease in PDE activities in LV and a ≈ 50% reduction in PDE3 and PDE4. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neurons
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Cryomyolysis, a new procedure for the conservative treatment of uterine fibroids
منشور في 1998"…Normal uterine volume ranged from 35.6 to 548.7 ml preoperatively and 45.1 to 729.6 ml postoperatively (mean increase 40%); however, myoma volume showed a mean decrease of 6% (range-87-28%). Analysis of only frozen myomata revealed a mean volume decrease of 10%. …"
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Performance analysis of a new designed PEM fuel cell
منشور في 2012"…In this paper, a new design for the flow channels is presented, and a parametric study of the proton exchange membrane (PEM) fuel cell is conducted in order to investigate the effect of the new flow channels, as well as different operating parameters, on the efficiency and energy output of the cell. …"
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A new perspective on cardiovascular drift during prolonged exercise
منشور في 2021"…</p><h2>Other Information</h2><p dir="ltr">Published in: Life Sciences<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.lfs.2021.120109" target="_blank">https://dx.doi.org/10.1016/j.lfs.2021.120109</a></p>…"
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A New Extension of Generalized Exponential Distribution with Application to Ozone Data
منشور في 2017"…In this article, a new distribution, called transformed Generalized Exponential Distribution () is proposed. …"
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
منشور في 2021"…These findings demonstrate for the first time that VISTA is suppressed by metformin and identified a new regulatory mechanism through AHR. The data suggest that metformin could be a new potential therapeutic strategy to treat melanoma patients combined with targeted immune checkpoint inhibitors.…"
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
منشور في 2023"…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). …"
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Investigation of Forming a Framework to shortlist contractors in the tendering phase
منشور في 2022"…The aim of this research is to create a framework that can predict the best contractor to be awarded a construction contract by a consultant/client using a different set of variables known as “Decision factors.” …"
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A new quadratic asymmetric error correction model: does size matter?
منشور في 2022"…<p dir="ltr">We introduce a new quadratic asymmetric error correction model that comprehensively accounts for both sign and size asymmetries. …"
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Thermodynamic analysis of a new renewable energy based hybrid system for hydrogen liquefaction
منشور في 2012"…In this paper, a parametric study of the triple effect absorption cooling system (TEACS) integrated with solar photo-voltaic/thermal (PV/T), geothermal, and Linde–Hampson cycle is conducted. …"
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When Should a Brain MRI Be Performed in Children with New-Onset Seizures? Results of a Large Prospective Trial
منشور في 2021"…BACKGROUND AND PURPOSE: There is a paucity of data regarding the incidence of structural brain lesions in children with new-onset unprovoked seizures. …"
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …"
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New media and new practices of exploitation
منشور في 2015"…Increasing use of new media and increasing Internet penetration through rising sales numbers of mobile devices caused a necessity for a new debate. …"
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The effect of Ramadan focused education on patients with type 2 diabetes: A systematic review and meta-analysis
منشور في 2020"…</p><h3>Conclusions</h3><p dir="ltr">This systematic review and meta-analysis shows that Ramadan-focused diabetes education leads to a decrease in HbA1c and LDL, but an increase in TG and weight during Ramadan. …"