apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes حسب Manjunath Ramanjaneya (14603468)

"…</p><h3>Conclusions</h3><p dir="ltr">Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …"

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit Masania (7164239)

"…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …"

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …"

An additive manufacturing approach based on electrohydrodynamic printing to fabricate P3HT:PCBM thin films حسب Zulfikre Esa (19457344)

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate حسب Geethakumari, Anupriya M

"…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…"
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Fabrication of Ag₂O/WO₃ based sensors for detection of hydrogen sulfide حسب Ahmad Al-Sarraj (17151007)

Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis حسب George Nitzburg (18614989)

Operation optimization of propane pre-cooled mixed refrigerant LNG Process: A novel integration of knowledge-based and constrained Bayesian optimization approaches حسب Roba Shady (22048043)

"…Thus, for the first time, this study proposes systematic knowledge-based and constrained Bayesian optimization approaches to identify the optimal operation of the C3MR process. …"

eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways حسب Zvi Cramer (10742876)

"…These effects are likely dependent on the inhibition of eIF4A activity since we observed similar results using PatA. …"

Nurse-Led System-wide Unit-based Hospital Acquired Pressure Injury (HAPI) Reduction Project حسب Mariam Al-Mutawa (18505317)

"…</p><h3>Methods</h3><p dir="ltr">A quality improvement project was conducted using the Agency for Healthcare Research and Quality (AHRQ) Comprehensive Unit-based Safety Program (CUSP) model to implement the HAPI Project. 3 Unit-based HAPI champions were identified, drove the implementation of this project across HMC. …"

Genome-Wide Association Study of Vitamin D Deficiency in the Middle East With a Relevant Characterization of the Novel <i>SDR42E1 </i>Gene حسب Nagham Nafiz Ahmad Hendi (19938204)

"…Cellular viability also decreased significantly after the knockout of SDR42E1 in the HCT116 cells.…"

3D Tissue-Engineered Vascular Drug Screening Platforms: Promise and Considerations حسب Isra Marei (11312895)

"…A novel approach is to develop 3D tissue engineered miniaturized constructs in vitro that are based on human cells. …"

3D printing of circular materials: Comparative environmental analysis of materials and construction techniques حسب Shoukat Alim Khan (14778226)

"…Life Cycle Assessment (LCA) was carried out for three cases of CDW-based 3D printed structures, Portland cement-based 3D printed structures, and conventional masonry construction methods and materials, to analyze the environmental impact of CDW-based 3D-printed designs and their comparative analysis. …"

DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation حسب Abdelilah Arredouani (10914455)

"…Here, we assessed the effect of DNAJB3 on the respective activity of JNK1 and IKKβ in cell-based assays. …"

Orthodontic camouflage versus orthodontic-orthognathic surgical treatment in borderline class III malocclusion: a systematic review حسب Maged S. Alhammadi (14150757)

"…PubMed, Scopus, Science Direct, Web of Science, Cochrane, and LILACS were searched up to October 2021. …"

Addressing Challenges of Distance Learning in the Pandemic with Edge Intelligence Enabled Multicast and Caching Solution حسب Kashif Bilal (16896357)

"…Due to the closure of educational institutes, work and learn from home methods have burdened the network resources and considerably decreased a viewer’s Quality of Experience (QoE). The situation calls for innovative techniques to handle the surging load of video traffic on cellular networks. …"

Electrochemical and thermodynamic study on the corrosion performance of API X120 steel in 3.5% NaCl solution حسب Khuram Shahzad (575887)

"…</p><h2>Other Information</h2><p dir="ltr">Published in: Scientific Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1038/s41598-020-61139-3" target="_blank">http://dx.doi.org/10.1038/s41598-020-61139-3</a></p>…"

Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells حسب Ejlal Abu-El-Rub (5168183)

"…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…"

Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model حسب Sahar Isa Da’as (18288880)

"…The examination of zebrafish adults showed a thickened ventricular cardiac wall with reduced heart rate, swimming speed, and endurance ability in both the mypbc3 heterozygous and homozygous groups. Furthermore, heart transcriptome profiling showed a significant downregulation of the actin-filament-based process, indicating an impaired actin cytoskeleton organization as the main dysregulating factor associated with the early ventricular cardiac hypertrophy in the zebrafish mypbc3 HCM model.…"