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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …”
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HbA1c over 8.5% is not predictive of increased infection rate following penile prosthesis implant surgery in diabetic patients with erectile dysfunction
Published 2021“…<p dir="ltr">Diabetes mellitus is associated with increased risk of erectile dysfunction. Penile prosthesis implantation is an efficient therapeutic option for erectile dysfunction, but not without risk, as infection remains a prominent concern. …”
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Using a Time Timer™ to increase appropriate waiting behavior in a child with developmental disabilities
Published 2009“…This study aimed to examine the use of a predictive stimulus (Time Timer™) and delayed reinforcement to increase appropriate waiting behavior in a child with developmental disabilities and problem behavior maintained by access to tangible items and activities. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neurons
Published 2019“…<div><p>Selenium application as sodium selenate was repeatedly shown to have anti-carcinogenic properties by increasing levels of the serine/ threonine protein phosphatase 2A (PP2A) in cancer cells. …”
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Potential of horizontal louvers in increased energy savings in a commercial building in Dubai
Published 2018“…The dissertation creates a benchmark for horizontal louver configuration and its role in increasing the energy savings. …”
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Towards Monitoring of Nutrient Pollution in Coastal Lake Using Remote Sensing and Regression Analysis
Published 2020“…The last few decades have witnessed a tremendous increase in nutrient levels (phosphorus and nitrogen) in coastal water leading to excessive algal growth (Eutrophication). …”
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Effect of increasing the number of anchors on the flexural performance of FRP-strengthened RC beams
Published 2024“…Three concrete beams having a length, depth, and width of 2000, 250, 200 mm, respectively, were tested under a four-point bending test. …”
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Increased Fracture Risk After Bariatric Surgery: a Case-Controlled Study with a Long-Term Follow-Up
Published 2022“…This study aimed to investigate whether bariatric surgery increases fracture risk.</p> <h2>Material and Methods</h2> <p>It was a case-controlled study. …”
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Nrf-2-dependent antioxidant and anti-inflammatory effects underlie the protective effect of esculeoside A against retinal damage in streptozotocin-induced diabetic rats
Published 2024“…Esculeoside A (ESA) is a tomato-derived glycoside with antioxidant and anti-inflammatory properties. …”
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A control algorithm to increase the efficient operation of wind energy conversion systems under extreme wind conditions
Published 2022“…</p><h2>Other Information</h2><p dir="ltr">Published in: Energy Reports<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.egyr.2022.08.243" target="_blank">https://dx.doi.org/10.1016/j.egyr.2022.08.243</a></p>…”
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Expression of 3-Methylcrotonyl-CoA Carboxylase in Brain Tumors and Capability to Catabolize Leucine by Human Neural Cancer Cells
Published 2022“…When 13C6-leucine was offered, it led to an increased appearance of the heavier citrate isotope with a molar mass greater by two units in the culture media. …”
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Increasing consultant-level staffing as a proportion of overall physician coverage improves emergency department length of stay targets
Published 2021“…</p><h3>Results</h3><p dir="ltr">Multivariate logistic regression adjusting for a number of operations factors (including total EP on-duty complement) identified an association between increasing n of on-duty Consultants and the likelihood of a shift’s meeting the 4-h ED LOS target (OR 1.27, 95% CI 1.20 to 1.34, p < .0001). …”
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Greensporone A, a Fungal Secondary Metabolite Suppressed Constitutively Activated AKT via ROS Generation and Induced Apoptosis in Leukemic Cell Lines
Published 2019“…Interestingly, gene silencing of AKT using AKT specific siRNA suppressed the expression of Bcl-2 with enhanced expression of Bax. Greensporone A-mediated increase in Bax/Bcl-2 ratio causes permeabilization of the mitochondrial membrane leading to the accumulation of cytochrome c in the cytoplasm. …”
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Corporate culture at Universal Bank, S.A.L. (c1994)
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Cardiac phosphodiesterases are differentially increased in diabetic cardiomyopathy
Published 2021“…Moreover, we noted an early and specific upregulation of cardiac PDE1A, PDE2A, PDE4B, PDE4D and PDE5A expression at week 4, followed by increases in PDE3A levels in diabetic hearts at week 8. …”
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