Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

“…These findings demonstrate for the first time that VISTA is suppressed by metformin and identified a new regulatory mechanism through AHR. The data suggest that metformin could be a new potential therapeutic strategy to treat melanoma patients combined with targeted immune checkpoint inhibitors.…”
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
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Geomorphological changes in the coastal area of Farasan Al-Kabir Island (Saudi Arabia) since mid Holocene based on a multi-proxy approach by Pavlopoulos, Kosmas

“…The geomorphological evolution of the southeastern coastal area of Farasan Al-Kabir Island (Saudi Arabia) is revealed by the mapping of modern landforms and a multi-proxy and high spatial resolution study including grain size, particulate organic carbon, mineralogy, element geochemistry, benthic foraminifera analysis and radiocarbon dating of a 3.3-m long sediment core. …”
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Effect of AlN nanoparticle concentration in the electrolyte on corrosion resistance and mechanical properties of the electrodeposited composite coatings by Khan, M.S.

“…This research aims to develop an innovative solution by incorporating AlN nanoparticles with various concentrations (0.1, 0.2, 0.4, and 0.8 g/L) as reinforcement in the Ni-P electrolyte to develop composite coatings using A36 carbon steel as a substrate through direct current (DC) electrodeposition method. …”
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Mixed siliciclastic-carbonate-evaporite sedimentation in an arid eolian landscape: The Khor Al Adaid tide-dominated coastal embayment, Qatar by John M., Rivers

“…The Khor Al Adaid embayment of southern Qatar represents a unique shallow-water mixed siliciclastic‑carbonate coastal depositional system that developed in a hyper-arid climatic setting over the past 6000 years. …”
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Development of new reliability metrics for microgrids: Integrating renewable energy sources and battery energy storage system by Mohammadreza, Gholami

“…Microgrids (MGs) are gaining popularity due to their ability to provide reliable and resilient power supply, especially when integrated with renewable energy sources (RESs) and battery energy storage systems (BESS). Reliability is a critical factor for MG owners and policy makers. …”
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Effects of the addition of a high energy density fuel, adamantane to diesel on its cetane number, sooting propensity, and soot nanostructural properties by Al Zaabi, Alanood

“…The addition of up to 6.75 wt% of adamantane in diesel significantly increased the smoke point of diesel from 18 to 29 mm (and threshold sooting index decreased by 44%), indicating a drastic drop in fuel sooting tendency. …”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... by Salma, Younes

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Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study by Rajesh, Sharma

“…Between 1990 and 2019, deaths due to 17 of the 29 cancers either doubled or more, and 20 of the 29 cancers underwent an increase of 150% or more in terms of new cases. Tracheal, bronchus, and lung cancer (both sexes), breast cancer (among females), colon and rectum cancer (both sexes), stomach cancer (both sexes) and prostate cancer (among males) were among top-5 cancers in most Asian countries in terms of ASIR and ASMR in 2019 and cancers of liver, stomach, hodgkin lymphoma and esophageal cancer posted the most significant decreases in age-standardized rates between 1990 and 2019. …”
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Health in times of uncertainty in the eastern Mediterranean region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 by Mokdad, Ali H

“…Since our Global Burden of Disease Study 2010 (GBD 2010), the region has faced unrest as a result of revolutions, wars, and the so-called Arab uprisings. …”
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Trends in the global, regional, and national burden of oral conditions from 1990 to 2021: a systematic analysis for the Global Burden of Disease Study 2021 by Eduardo, Bernabe

“…Increasing counts of prevalent cases and DALYs were noted for all oral conditions but untreated caries of deciduous teeth (no percentage change in prevalence or DALYs) and orofacial clefts (–68·3% [–79·3 to –46·5] decrease in DALYs). There were decreases in both age-standardised prevalence and DALY rate for untreated caries of permanent teeth and edentulism, no change in both for untreated caries of deciduous teeth and severe periodontitis, an increase in the prevalence but no change in the DALY rate for lip and oral cavity cancer, and no change in the prevalence but a decrease in the DALY rate for orofacial clefts. …”
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Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021 by Sirota, Sarah Brooke

“…The mortality rate of URIs in 2021 was 0·2 per 100 000 (0·1 to 0·5), a decrease of 64·2% (–84·6 to –43·4) from 1990, when the mortality rate was 0·7 per 100 000 (0·2 to 1·1). …”
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Energy saving potential analysis applying factory scale energy audit – A case study of food production by Derar, Al Momani

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Mental health, burnout and resilience in community pharmacists during the COVID-19 pandemic: A cross-sectional study by Zeana, Samir AlKudsi

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Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal... by Haidong, Wang

“…Background Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. …”
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Control of the Speed of a Light-Induced Spin Transition through Mesoscale Core-Shell Architecture by Slimani, Ahmed

“…The ability to tune the rate of optically induced magnetic and structural phase transitions through control of mesoscale architecture presents a new approach to the development of photoswitchable materials with tailored properties. © 2018 American Chemical Society.…”
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Empirical evaluation of change in crash risk due to lane marking reallocation: A case study in Kochi City, Japan by Hiroaki, Nishiuchi

“…Video data were collected before and after the implementation of a new road layout (achieved by reallocating lane markings) that was intended to mitigate traffic congestion at a signalized intersection. …”
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Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 by Stein Emil, Vollset

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Numerical analysis of spatial distribution of carbon in methane dry reforming over supported nickel catalyst in a packed bed reactor by Ebrahimi, Parisa

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Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 by Fiona B, Bennitt

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