Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function. by Seidel, Monika

“…The cardiac ryanodine receptor (RyR2), which mediates intracellular Ca2+ release to trigger cardiomyocyte contraction, participates in development of acquired and inherited arrhythmogenic cardiac disease. …”
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Dynamic workload patterns prediction for proactive auto-scaling of web applications by Iqbal W.

“…The framework is implemented and experimentally evaluated using historical access logs of three real web applications, each with increasing, decreasing, periodic, and randomly varying arrival rate behaviors. …”
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Decreased soil moisture due to warming drives phylogenetic diversity and community transitions in the tundra by Scharn, Ruud

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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
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INVESTIGATION OF SPATIOTEMPORAL VARIABILITY AND CONTAMINATION OF PLASTIC MARINE DEBRIS IN QATAR’S COASTAL WATERS by Abayomi, Oyebamiji Abib

“…There has been a tremendous proliferation in plastic production in the last five decades due to its low cost and versatile applications. …”
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Mercury pollution in doha (Qatar) coastal environment by Al-Madfa, H.

“…Dissolved reactive Hg (2.9 ng L?1) represented 81.0% of the total dissolved Hg (3.5 ng L?…”
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Investigation of Spatiotemporal Variability of Microplastics in Qatar's Cstal Environment by Ben-Hamadou, Radhouane

“…There has been a tremendous proliferation in plastic production in the last five decades due to its low cost and versatile applications. …”
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Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics by Nomikos, Michail

“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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Differentiation of human olfactory bulb-derived neural stem cells toward oligodendrocyte. by Marei, Hany E

“…The differentiation medium, containing cAMP, PDGFA, T3, and all-trans-retinoic acid (ATRA), promotes OBNSCs to generate mostly oligodendrocytes (OLs) displaying morphological changes, and appearance of long cytoplasmic processes. OBNSCs showed, after 5 days in OLs differentiation medium, a considerable decrease in the number of nestin positive cells, which was associated with a concomitant increase of NG2 immunoreactive cells and few O4(+)-OPCs. …”
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Effect of Hyperglycemia on eNOS function in EPCs by Elshiekh, Duaa Ibnomer

“…Cells were treated with normal glucose (NG, 5.5mM) and high glucose (HG, 25mM) media for 3 & 6 days, and the effect on eNOS and Akt phosphorylation were assessed using western blot. …”
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Roadmap toward energy-positive upfront nitrogen removal process in baseload LNG plant by Mkacher, Hajer

“…The results show that UNrem of 87.5% from the NG feed can reduce the total power requirements by 0.24%, increase the production flow rate by 4.4%, and decrease the exergy losses by 0.23% compared with the base case. …”
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Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study by Houssein H., Ayoub

“…Increasing condom use from 10 % to 50 % lowers NG prevalence among FSWs, clients, and their spouses from 12.2 % to 6.4 %, 1.2 % to 0.5 %, and 0.4 % to 0.2 %, respectively. …”
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In vitro effects of hydrogen peroxide on rat uterine contraction before and during pregnancy by AlanaziR.

“…Results In both term-pregnant and non-pregnant uterine strips, H 2 O 2 elicited a biphasic response, consisting of a transient contraction followed by a persistent decrease in spontaneously generated contractions, contractions induced by oxytocin, and contractions induced by high Ca +2 (all P< 0.01, compared with controls) in a concentration-dependent manner. …”
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RIGOROUS SIMULATION AND OPTIMIZATION OF THE COLD SECTION IN A REAL LNG PLANT: UPFRONT NITROGEN REMOVAL AS PROCESS ENHANCING CONCEPT by MKACHER, HAJER

“…Compared with baseline operation, removing up to 87.5% of nitrogen from the feed was found optimal as it decreases the total power requirement by 0.24 MW and increases the LNG product flow rate by 4.4 %, while exergy loss decreased by 7.08 MW. …”
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Possible Ionic Effects of NaCl on Two Mexican Wheat Cultivars by Yasseen, B.T. [بسام طه ياسين]

“…The ionic agents, NaCl and Na2SO+, decreased K* and Ca2* in the leaves, while PEG had little effect on leaf iontent of r* ana- Ca2i lif in.r. ug"",t increased phosphorus in leaves of both cultivars, but PEG had the smallest effect. …”
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The Effects of Statin Therapy on Circulating Levels of Trimethylamine N-oxide: A Systematic Review and Meta-analysis by Jamialahmadi, Tannaz

“…This meta-analysis aimed to provide an answer as to whether statins do affect decreasing the plasma levels of atherogenic TMAO. Methods A systematic literature search in PubMed, Scopus, Embase, and Web of Science was performed from inception to January 1st, 2023. …”
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Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function by Da'as, Sahar I.

“…Furthermore, circular dichroism spectroscopy experiments using recombinant CaM proteins reveals a decreased structural stability of the four mutants compared to the wild-type CaM protein in the presence of Ca2+. …”
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Osteoporosis in patients with stroke: A cross-sectional study by Tomasevic-Todorovic, Snezana

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