PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications by Pramod Darvin (153341)

“…<p>Tumor progression through immune evasion is a major challenge in cancer therapy. Recent studies revealed that enhanced PD-L1 expression in cancer stem cells is linked to immune evasion. …”

Western diet induces mild metabolic impairment and aggravates neuropathology in an experimental mouse model of traumatic brain injury by Judith, Nwaiwu

“…WD has been shown to impair cognitive function, decrease the brain's capacity to compensate for insult by affecting recovery as well as induce metabolic syndrome (MetS) which may be a risk factor for poor TBI prognosis. …”
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Design and analysis of PV fed high-voltage gain DC-DC converter using PI and NN controllers by Madisa V.G., Varaprasad

“…When the converter switch comes under active state two capacitors are discharged in series, similarly when the converter switch under inactive state those two capacitors are charged in parallel through the coupled inductor (CI) energy so, to get a high voltage at the converter output side. To reuse the leakage-inductor (LI) energy of the CI with the help of a passive clamp circuit for reducing the voltage stress across the switch, similarly switch has less resistance so conduction losses also decreased. …”
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Bone Benefits of Fish Oil Supplementation Depend on its EPA and DHA Content by Haissam Abou-Saleh (497840)

“…Further, CFO supplementation was associated with an increase in the production of IL-10, IL-12, and IFN-γ and a decrease in the production of TNF-α and IL-6, and the activation of NF-κB, p38 MAPK, and JNK signaling pathways. …”

Innovative strategies to reduce traffic related injuries and deaths in youth by Joanne Banfield (19794507)

“…This is consistent with the cognitive dissonance theory, which states that changing the beliefs that underlie certain behaviors can cause a behavioral change (2). From these theories, one can expect that changing the risk taking attitudes of adolescents can lead to a decrease in the probability of collisions. …”

Analyzing the effectiveness of various coatings to mitigate photovoltaic modules soiling in desert climate by Alaa Elsafi (22282354)

“…Soiling was measured in terms of loss in light <u>transmittance</u>, measured by UV–Vis spectroscopy, and increase in surface coverage area, measured using optical microscopy. The results indicate a decrease in light transmittance and an increase in surface coverage area over time due to dust accumulation. …”

Anti-angiogenic effect of nano-formulated water soluble kaempferol and combretastatin in an in vivo chick chorioallantoic membrane model and HUVEC cells by Gowtham Kumar Subbaraj (17807615)

“…In addition, the mRNA expression levels of VEGF-A and FGF2 were significantly decreased compared with native forms. …”

YOLO-DefXpert: An Advanced Defect Detection on PCB Surfaces Using Improved YOLOv11 Algorithm by Prabu Selvam (22330264)

“…Compared to the standard YOLOv11 model, the proposed YOLO-DefXpert attained an improvement of 9.3% and 13.2% in mAP50 and mAP95, an 11.25% increase in frames per second, and a 69.85MB decrease in model size. These findings highlight a notable enhancement in both accuracy and model efficiency in detecting tiny defects in the PCB board.…”

Effect of speed and gradient on plantar force when running on an AlterG® treadmill by Athol Thomson (6651008)

“…Gradient made little difference except for a downhill grade of − 5% decreasing force peaks as compared to level or uphill running.…”

Postprandial lipaemia 10 and 34 hours after playing football: Does playing frequency affect the response? by Darren J. Paul (6905450)

“…For the 3FOOT, there was a non significant decrease in postprandial TG AUC (-2.7%; p = 0.73; 95%CI = -2.0 to 1.5; ES = 0.05) and iAUC (-17.5%; p = 0.41; 95%ci = -2.5 to 1.1; ES = 0.31) from 10 to 34 hrs, respectively. …”

Qatar’s immigrants at higher risk of diabetes by Nature Research (16552612)

“…Those of South Asian descent had a 13-fold increased risk of having elevated glycated haemoglobin levels, and Filipinos a 4.5-fold increase, compared to the native Arab population. …”

Improvement of heat sink performance using paraffin/graphite/hydrogel phase change composite coating by Sreedevi Paramparambath (17346997)

“…High temperature brings adverse impacts on energy efficiency, and even destroys a semiconductor device. The synthesized W-G-H composite is proposed to decrease the working temperature of semiconductor devices. …”

Intelligent route to design efficient CO₂ reduction electrocatalysts using ANFIS optimized by GA and PSO by Majedeh Gheytanzadeh (17541927)

“…<p dir="ltr">Recently, electrochemical reduction of CO₂ into value-added fuels has been noticed as a promising process to decrease CO₂ emissions. …”

Novel Wire Gripper for Robotics Picking of Small Green Parts From Powder Bed of Binder Jet Metal Additive Manufacturing by Abdulhamid Mathkur (22467373)

“…A combination of 304 stainless steel wires integrated with a PLA body allows the device to achieve precise handling and control together with versatile operation. …”

Using primary healthcare facilities and patients’ expectations about triage system: Patients’ perspective from multisite Jordanian hospitals by Mohammad Minwer Alnaeem (19143733)

“…A convenience sample of 726 patients were enrolled and completed a self-administrated questionnaire. …”

Boron doped silver-copper alloy nanoparticle targeting intracellular S. aureus in bone cells by Tahir Abdulrehman (8697696)

“…The ACB-OBAb nanoparticles showed a 1.32 log reduction of intracellular S. aureus at a concentration of 1mg/L. …”

Retinal imaging based glaucoma detection using modified pelican optimization based extreme learning machine by Debendra Muduli (20748758)

“…This method is entitled extracting curve-like features and creating a feature set. The combined feature reduction techniques named as principal component analysis and linear discriminant analysis, have been applied to generate prominent features and decrease the feature vector dimension. …”

Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice by Julie Decock (44558)

“…Using quantitative real-time RT-PCR, we tracked the expression of the entire Mmp and Timp gene families, observing a significant decrease in Mmp3 expression in Mmp8-null tumors compared to wild-type and heterozygotes throughout the time course of the model, which was confirmed at the protein level. …”

Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats by Ines Fki (14571855)

“…Equally, it showed a rise of the apoptotic markers (a decrease in the expression of the Bcl-2 and an increase of the P53). …”

Fasting-Mimicking Diet Is Safe and Reshapes Metabolism and Antitumor Immunity in Patients with Cancer by Claudio Vernieri (9744243)

“…In 101 patients, the FMD was safe, feasible, and resulted in a consistent decrease of blood glucose and growth factor concentration, thus recapitulating metabolic changes that mediate fasting/FMD anticancer effects in preclinical experiments. …”