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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …"
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2
Iterative Querying in Web-Based Database Application
منشور في 2002"…Web applications are increasingly relying on databases. …"
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conferenceObject -
3
A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …"
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Ripple effect in web applications
منشور في 2010"…The number of internet web applications is rapidly increasing in a variety of fields and not much work has been done for ensuring their quality, especially after modification. …"
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Towards context-adaptable Web service policies
منشور في 2011"…These policies can then be statically woven into compositeWeb services (e.g. a BPEL process). The synergy between context, policies and aspects allows to increase the level of adaptability of Web services at different levels of applications.…"
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Web service discovery: Rationale, challenges, and solution directions
منشور في 2024"…Web Service technology paved the way for microservice architecture as it is a feature of modern web applications that resulted from the rise of SOA. …"
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Computing ripple effect for web applications. (c2007)
منشور في 2007احصل على النص الكامل
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masterThesis -
11
On the sampling and integration rates of process noise
منشور في 1995"…It is shown that the covariance of a sampled zero-mean exponentially-correlated process is independent of the sampling rate. Moreover, when integrating this sequence, then the respective covariance decreases proportionally to the integration period. …"
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conferenceObject -
12
Using XML-based multicasting to improve web service scalability
منشور في 2012"…A major WS feature is SOAP, a simple, robust and extensible XML-based protocol for the exchange of messages. …"
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Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal...
منشور في 2020"…We classified location-years into seven categories on the basis of the natural rate of increase in population (calculated by subtracting the crude death rate from the crude birth rate) and the net migration rate. …"
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14
Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …"
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A review of technical and quality assessment considerations of audio-visual and web-conferencing focus groups in qualitative health research
منشور في 2023"…Four key concepts (qualitative health-related research, online platforms, platform analysis, and quality measures) were used. A consensus group method, and a review of user guides of three of the currently used online platforms (i.e., “WebEx”, “Zoom”, and “Microsoft Teams”) were employed to develop a set of specific core quality criteria for appraising online qualitative research studies. …"
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Investigation of infiltration rates under different experimental conditions
منشور في 2016"…This paper presents the results of laboratory experimental studies on soil infiltration rates (IR) using constant-head (CH) and falling-head (FH) methodologies. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. By the end of March 2021, these variants were accounting for about two-thirds of SARS-CoV-2 variants circulating worldwide. …"