The effect of hydroxychloroquine on lupus erythematosus-like skin lesions in MRL/lpr mice حسب Tatsuya Shimomatsu (1545943)

"…The average number of mast cells was 81, 50, and 12 (magnification, ×100), the mortality rate was 24%, 8%, and 9% and the mean body weight gain was 4.6 g, 8.0 g and 5.1 g, respectively.…"

Glycosaminoglycan (GAG) production from cultured chondrocytes under different oxidative conditions حسب Kazuo Yudoh (8787)

"…The HOtreated group exhibited a significant decrease in GAG production by chondrocytes as compared with the control group at all incubation times. …"

PFMA-3 induced glutathione and lipid peroxidation production greater than XRT. حسب Francesca Buontempo (3532004)

"…The regeneration currents recorded were reported as a percentage increase/decrease of the signal in respect to the one recorded at the same tip-dish distance but far away from cells (I_T/I_Tdish). …"

TBr inhibited cell proliferation in leukemia cell lines. حسب Anup S. Pathania (657368)

"…<p>(A–B) Cell proliferation assay. Cells were treated with 1, 10, 30, 50 and 100 µM concentrations of TBr for 24 and 48 h. …"

Electroretinogram recordings of <i>mglur6b</i>-depleted zebrafish larvae. حسب Ying-Yu Huang (171396)

"…<p>The downregulation of mGluR6b leads to a dose dependent decrease of the ERG b-wave in 5 day old zebrafish larvae indicating a diminished ON-response. …"

ErbB signaling is implicated in generation of neurons and mitoses in the sub-ventricular zone. حسب Tomomi Sato (301255)

"…Dotted circle, OT. Scale bar, 100 μm. <b>B</b>. Quantification of <i>pou4f1-hsp70l</i>:GFP intensity in the OT for the experiment shown in A (mean ± s.e.m.; **<i>P</i> < 0.01, ***<i>P</i> < 0.001; n = 8, 10, 16 for AG1478, AG43, DMSO, respectively). …"

DAAP1 depletion results in reduced attachment. حسب Melissa C. Steele-Ogus (12295373)

"…Unattached cells had a greater decrease in DAAP1 expression (38% ± 6) than attached cells (23% ± 2). …"

Soluble klotho blocks DAG stimulation of exocytotic insertion of pre-docked TRPC6 vesicles. حسب Jian Xie (629484)

"…<p>(A, B) Tetanus toxin (TTX) acts on synaptobrevin (“Sb2” for synaptobrevin-2) to decrease surface expression of TRPC6 channels. …"

Changes in the Bacterial Community Structure of Remediated Anthracene-Contaminated Soils حسب Laura Delgado-Balbuena (3211080)

"…On the one hand, application of earthworms removed most of the contaminant from the arable soil and had a strong effect on the bacterial community structure, i.e. a decrease in the relative abundance of the Acidobacteria, Chloroflexi and Gemmatimonadetes, and an increase in that of the Proteobacteria compared to the unamended soil. …"

Morpholino knock down of kermit2 inhibits gastrulation and FN matrix assembly. حسب Erin Spicer (248823)

"…Embryos injected with 20 ng of Kermit2 5 mismatch control morpholino (COMO; B) gastrulate normally, and (E) exhibit a small decrease in FN matrix assembly. …"

Quantitative image analysis of ovaries from <i>mir-202 -/-</i> juvenile females. حسب Stéphanie Gay (5733569)

"…The number of small follicles (50–100 μm) is significantly higher compared to wild-type, while the number of follicles in the larger diameter class (200–350 μm) tends to decrease. …"

<i>Mecp2</i> deficient neurons and astroglia cells have significantly more chromocenters than wild type cells. حسب Bianca Bertulat (126768)

"…All analyzed samples show a highly significant (p<0.0001) difference of mean values. …"

Effects of TNF-α and atRA on matrix gene expression حسب Jason S Rockel (18877)

"…Panels b to d: data are ratios of matrix gene: transcript levels normalized as a fraction of the ratios in untreated cultures (first bar), and are expressed as means ± standard error (the number of independent experiments was seven for panel b, five for panel c, and five for panel d). …"

Febuxostat suppresses LPS-induced MCP-1 production via MKP-1-dependent inhibition of JNK through increasing MKP-1 activity. حسب Johji Nomura (462919)

"…<p>Cells incubated for 30 min with vanadate (200 µM) or Ro-31-8220 (1 µM) were pretreated for 10 min with febuxostat (30 µM) or NAC (10 mM), and then stimulated for 1 (A) or 2 h (B) with 100 ng/mL LPS. (A) Western blot analysis using anti-phospho-JNK and β-actin antibodies. …"

Effect of CPP (Light) on GPDH activity in 3T3-L1 preadipocytes. حسب Kasumi Fujita (10271129)

"…<p>The activity of GPDH was calculated using the extinction coefficient of NADH, 6.22 mM^-1 cm^-1, and was calculated based on the decrease in NADH every 3 min. Enzyme activity is expressed as a value relative to the control (100%). …"

Reconsolidation and extinction after different strengths of training. حسب Remus Osan (3639754)

"…Bars indicate freezing in vehicle (dark blue) and anisomycin (light blue) groups before (left set) and after (right set) reexposure with <i>t</i> = 4 (mean ± S.E.M. of 100 simulations). As occurs in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0023113#pone-0023113-g003" target="_blank">Figure 3C</a>, freezing is decreased by anisomycin administration, indicating reconsolidation blockade. …"

One-way sensitivity analysis to all model parameters. حسب Anna Miquel-Cases (2635486)

"…The NMB remained cost-effective at all parameters values tested, except at specificity of 55% and sensitivity of 100%, were the NMB became negative. Furthermore, an increase in the proportion of relapses and deaths in the conventional-NACT strategy, an increase in the costs of the R health-state and a decrease in the costs of NX markedly increased cost-effectiveness.…"

Color space representation across different CNN layers and different CNN architectures. حسب JohnMark Taylor (8329326)

"…The averaged correlation over all objects for each layer is plotted in a line graph on the right of each scenario. In the first scenario, the color space structure within each object differs substantially across processing, resulting in a large decrease in correlation across layers. …"

Gu-4 inhibited HMGB1 release and translocation in LPS-stimulated macrophages. حسب HuiTing Zhou (333755)

"…<p>A: Gu-4 does-dependently decreases the LPS-induced HMGB1 release from macrophages. …"

Dissecting Variation in Biomass Conversion Factors across China’s Forests: Implications for Biomass and Carbon Accounting حسب Yunjian Luo (550803)

"…Moreover, stronger climatic effects were found on BCFs for functional components (i.e. branch, foliage and root) than BCFs for combined components (i.e. aboveground section and whole trees). A general trend for BCFs was observed to decrease and then increase from low to high soil fertility. …"