Synthesis and <i>in vitro</i> anticancer activity of certain novel 1-(2-methyl-6-arylpyridin-3-yl)-3-phenylureas as apoptosis-inducing agents by Wagdy M. Eldehna (4260952)

“…<p>In connection with our research program on the development of novel anticancer candidates, herein we report the design and synthesis of novel series of 1-(2-methyl-6-arylpyridin-3-yl)-3-phenylureas <b>5a–l</b>. …”

The relationship between trophic structure and producer nutrient content. by Just Cebrian (265900)

“…The variable <i>producer nutrient content</i> has measurement error, but that error is much smaller than the measurement error in any of the dependent variables, thereby allowing for the use of the model <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004929#pone.0004929-Cebrian1" target="_blank">[5]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004929#pone.0004929-Zar1" target="_blank">[29]</a>. …”

Data_Sheet_1_Pre- and Interhospital Workflow Times for Patients With Large Vessel Occlusion Stroke Transferred for Endovasvular Thrombectomy.docx by Laura C. C. van Meenen (11336568)

“…To identify potential workflow improvements, we analyzed pre- and interhospital time metrics for patients with LVO stroke who were transferred from a PSC for EVT.…”

Influence of MgCl and ATP on primer unblocking by AZT-resistant RT by Valérie Goldschmidt (13343)

“…The decrease of the band intensity relative to the first time point (5 min) is plotted against the reaction time.…”

Drug sensitivity test in BAP1 knockdown GBC cell line. by Takashi Hirosawa (5931845)

“…No change in sensitivity was observed in GEM, CDDP, 5-FU, sodium valproate or 5-azacytidine. Bortezomib showed a significant decrease in sensitivity in the siRNA1 and siRNA2 group compared to the control.…”

Recruitment of mild malaria cases in dispensaries between September and December (2004). by Ndeye Sakha Bob (366261)

“…Malaria infection increased from October-November (12.6%) to December (16.7%, Chi2, p = 0.000014) in medical consultations, especially for older patients (from 13% to 21% for 5–15 y patients, Chi2 p = 0.000004; from 24% to 28.5% for 15–49 y, Chi2 p = 0.018) but not for infants (decrease from 10.7% to 2.7%, Chi2 p<0.0000001). …”

Msi2 silencing inhibits Akt, Erk1/2 and p38 signaling, which contributes to apoptosis mediated by Msi2 silencing in AML cells. by Yixiang Han (304056)

“…<p>(<b>A</b>) The phosphorylation of Akt, Erk1/2 and p38 were decreased followed by Msi2 silencing in Dami cells, HL-60 cells and primary AML cells from AML patients. …”

Retrograde actin flow in spreading cells visualized by enhanced phase contrast and fluorescence microscopy. by Antonina Y. Alexandrova (270568)

“…Arrowheads indicate zones of fast flow (lamellipodia) , dashed lines on images indicate the regions used to generate kymographs, arrows in kymographs indicate the slope of the isointensity lines reflecting the velocity of flow. (A) Swiss 3T3 fibroblast at 1.5 h of spreading displays wide lamellipodium, which is distinguishable from the lamellum by its density and texture (left image) and the velocity of retrograde flow (see Supplementary Data, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0003234#pone.0003234.s001" target="_blank">Movie S1A</a>). …”

Impact of catechins on anisotropy of model membranes. by Lucia Palacios (546672)

“…The DPH probe is located deep within the bilayer, whereas the TMA-DPH probe adopts a more superficial bilayer location. Compound <b>3</b> has almost no effect on anisotropy, but compound <b>5</b> elicits a major shift in the transition temperature and decreases anisotropy values in the gel phase and through the transition, indicating a decrease in lipid order and an increase in bilayer fluidity in comparison to compound <b>3</b> and vesicles alone.…”

Safety assessment and antimicrobial properties of the lactic acid bacteria strains isolated from polish raw fermented meat products by Anna Rzepkowska (3348017)

“…Strains were resistant to gastric enzymes and low pH (3–6 log CFU/mL decrease) and intestinal enzymes and bile salts (1–3 log CFU/mL decrease). …”

Six-month outcomes of corneal crosslinking with dextran-free isotonic riboflavin solution by Refik Oltulu (5763947)

“…The mean spherical equivalent refraction decreased from -5.6 ± 2.4 diopters (D) preoperatively to -5.0 ± 2.1 D, and mean simulated keratometry decreased from 48.5 ± 2.5 D to 47.8 ± 2.6 D at 6 months. …”

Glucose-dependent insulinotropic peptide in the high normal range is associated with increased carotid intima-media thickness by Amra Jujić (524347)

“…</p> <p><b>Conclusion </b>In a Swedish elderly population, physiologically elevated levels of fasting GIP are associated with increased IMT_meanCCA, while GLP-1 is associated with decreased IMT_maxBulb, further emphasizing diverging cardiovascular effects of these two incretin hormones.…”

Dataset for: The genetics of phenotypic plasticity. XVI. Interactions among traits and the flow of information by Samuel M. Scheiner (620380)

Ceramide induced cell death. by Farhan Rizvi (172611)

“…<p><b>A:</b> HCSF were grown to confluence in DMEM (without phenol red) containing 5%FBS, Mito+, and ciprofloxacin. …”

Evaluation of infiltrating inflammatory cells in ear sections. by Miriam Canavese (367824)

“…<p>Haematoxylin and Eosin staining on paraffin ear sections of Balb/c females 8–12 weeks of age sensitized and challenged in a DNFB-induced CHS. 30′ after challenge, mice were treated with [⁴⁴AANA⁴⁷]-CCL5 and Met-CCL5 at 0.05–0.5–1 mg/kg ip. …”

Table_1_Production, Storage Stability, and Susceptibility Testing of Reuterin and Its Impact on the Murine Fecal Microbiome and Volatile Organic Compound Profile.docx by Christoph Castellani (5940710)

“…</p><p>Results: The supernatant contained 13.4 g/L reuterin (3-hydroxypropionaldehyde; 3-HPA). 3-HPA content remained stable at −20°C for 35 days followed by a slow decrease of its concentration. Repeated freezing/thawing caused a slow 3-HPA decrease. …”

Image_1_Production, Storage Stability, and Susceptibility Testing of Reuterin and Its Impact on the Murine Fecal Microbiome and Volatile Organic Compound Profile.pdf by Christoph Castellani (5940710)

“…</p><p>Results: The supernatant contained 13.4 g/L reuterin (3-hydroxypropionaldehyde; 3-HPA). 3-HPA content remained stable at −20°C for 35 days followed by a slow decrease of its concentration. Repeated freezing/thawing caused a slow 3-HPA decrease. …”

Correlation of Cervical Cancer Mortality with Fertility, Access to Health Care and Socioeconomic Indicators by Diama Bhadra Vale (6879314)

“…In the multivariate analysis, only fertility rate was significantly associated with the CC mortality rate (coefficient of correlation: 9.38; 95% confidence interval [CI]: 5.16-13.59). Conclusion A decrease in the fertility rate, as expected when the level of development of the regions increases, is related to a decrease in the mortality rate of CC. …”

Alteration of cellular levels of Smad2/3, pSmad2/3, Smad4, and Smad7 in NRK cells exposed to β-HB then treated with DA extract. by Shu-Fen Liu (299474)

“…B–E: Data were scanned and normalized to β-actin. β-HB treatment resulted in increased expression of Smad2/3, pSmad2/3 and Smad4, and a decrease in Smad7 expression; importantly, DA extract significantly reversed β-HB-induced increases in Smad2/3, pSmad2/3 and Smad4, and the concomitant decrease in Smad7. …”

Anti-inflammatory effects of <i>Capparis ecuadorica</i> extract in phthalic-anhydride-induced atopic dermatitis of IL-4/Luc/CNS-1 transgenic mice by Bo Ram Song (6585197)

“…PA + MCE treated Tg mice showed decreasing infiltration of mast cells (42.5%), iNOS-mediated COX‐2 induction pathway, MAPK signalling pathway and inflammasome activation in the ear tissue.…”