Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…While screening off-target effects of rigid (<i>N</i>)-methanocarba-adenosine 5′-methylamides as A₃ adenosine receptor (AR) agonists, we discovered μM binding hits at the δ-opioid receptor (DOR) and translocator protein (TSPO). …”

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…While screening off-target effects of rigid (<i>N</i>)-methanocarba-adenosine 5′-methylamides as A₃ adenosine receptor (AR) agonists, we discovered μM binding hits at the δ-opioid receptor (DOR) and translocator protein (TSPO). …”

Even a Chronic Mild Hyperglycemia Affects Membrane Fluidity and Lipoperoxidation in Placental Mitochondria in Wistar Rats - Fig 6 by María del Consuelo Figueroa-García (832711)

Ripe Ora-pro-nobis (Pereskia aculeata miller) fruits express high contents of bioactive compounds and antioxidant capacity by Aline Priscilla Gomes da Silva (5221931)

Bald thigh syndrome in sighthounds—Revisiting the cause of a well-known disease by Magdalena A. T. Brunner (4532341)

“…Further research is required to clarify whether the <i>IGFBP5</i> variant represents a predisposing genetic risk factor. …”

Comparison of the time course of the SARS-CoV-2 pandemic up to 7 November 2020 for the seven regions in England for the time-varying IFR model between using death within 28 days of... by Siyu Chen (278663)

Stress-sensitive antidepressant-like effects of ketamine in the mouse forced swim test by Paul J. Fitzgerald (3239337)

“…This combination of fast action and a therapeutic effect that lasts far beyond the drug’s half-life points to a unique mechanism of action. …”

Synthesis, Crystal Structure, and Spectroscopic Characterization of a Series of Cubane-like Mo−Sb Clusters Containing a [Mo₃SbOS₃]⁷⁺ Core by Shao-Fang Lu (2974926)

“…Crystal data:  <b>1</b>, triclinic, <i>P</i>-1, <i>a</i> = 11.746(4) Å, <i>b</i> = 12.462(3) Å, <i>c</i> = 17.851(6) Å, α = 73.54(2)°, β = 75.06(3)°, γ = 88.11(3)°, <i>V</i> = 2419(3) ų, <i>Z</i> = 2, 4253 reflections, <i>R</i> = 0.055; <b>2</b>, triclinic, <i>P</i>-1, <i>a</i> = 12.76(1) Å, <i>b</i> = 17.86(1) Å, <i>c</i> = 11.882(4) Å, α = 75.05(4)°, β = 88.15(7)°, γ = 73.24(4)°, <i>V</i> = 2502(6) ų, <i>Z</i> = 2, 1849 reflections, <i>R</i> = 0.086; <b>3</b>, triclinic, <i>P</i>-1, <i>a</i> = 11.727(4) Å, <i>b</i> = 12.951(3) Å, <i>c</i> = 17.957(4) Å, α = 73.52(3)°, β = 76.22(3)°, γ = 89.00(2)°, <i>V</i> = 2536(3) ų, <i>Z</i> = 2, 6306 reflections, <i>R</i> = 0.053; <b>5</b>, triclinic, <i>P</i>-1, <i>a</i> = 13.261(4) Å, <i>b</i> = 13.529(4) Å, <i>c</i> = 12.535(8) Å, α = 101.54(3)°, β = 105.13(4)°, γ = 93.20(2)°, <i>V</i> = 2113(2) ų, <i>Z</i> = 2, 4104 reflections, <i>R</i> = 0.060.…”

A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country by Zaghloul, Nancy

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The effect of normobaric oxygen in patients with acute stroke: a systematic review and meta-analysis by Jiayue Ding (4689559)

“…Compared to controls, there was a minor trend toward NBO benefits in short-term prognostic indices, as indicated by decreased ΔNIHSS at our defined time points. …”

Photographs of the left eye 5 years (A–D) and 8 years (E) after systemic corticosteroid therapy in a patient shown in Fig 2. by Saho Saito (731215)

Image_5_Thermal preconditioning in a reef-building coral alleviates oxidative damage through a BI-1-mediated antioxidant response.jpeg by Eva Majerová (13895703)

Image_5_Phosducin-like 3 is a novel prognostic and onco-immunological biomarker in glioma: A multi-omics analysis with experimental verification.tif by Zesheng Peng (14792245)

Table_5_Phosducin-like 3 is a novel prognostic and onco-immunological biomarker in glioma: A multi-omics analysis with experimental verification.xlsx by Zesheng Peng (14792245)

Duration of different larval instars fed on different dsRNAs during 5^th instar. by Muhammad Naeem Sattar (19828497)

Hypothermia and hyperthermia impair neuronal functioning in normoxia. by Eva J. H. F. Voogd (20460665)

Carboxyhemoglobin (COHb) levels on the day of donation in packed red blood cells from smoker donors according to (A) number of cigarettes smoked per day (* different from < 10 and... by Renata E. Boehm (5793848)

The SNP rs402710 in 5p15.33 Is Associated with Lung Cancer Risk: A Replication Study in Chinese Population and a Meta-Analysis by Xuzai Lu (134340)

“…<div><p>Background</p><p>Lung cancer is the most commonly diagnosed cancer and leading cause of cancer mortality in the world. A single nucleotide polymorphism (SNP), rs402710, located in 5p15.33, was firstly identified to be associated with the lung cancer risk in a genome-wide association study. …”

Tomato HsfA1a plays a critical role in plant drought tolerance by activating <i>ATG</i> genes and inducing autophagy by Yu Wang (12152)

Image_1_A retrotransposon-derived DNA zip code internalizes myeloma cells through Clathrin-Rab5a-mediated endocytosis.tif by Pavan Kumar Puvvula (10495853)

“…Additionally, the loss of Rab5a decreased the Syntaxin-6 association with MMZC but not vice versa. …”