A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate حسب Geethakumari, Anupriya M

"…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…"
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Decreased Expression and Activity of cAMP Phosphodiesterases in Cardiac Hypertrophy and Its Impact on β-Adrenergic cAMP Signals حسب Abi-Gerges, Aniella

"…Methods and Results: Cardiac hypertrophy was induced in rats by thoracic aortic banding over a time period of 5 weeks and was confirmed by anatomic measurements and echocardiography. Ex vivo myocardial function was evaluated in Langendorff-perfused hearts. …"
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Shared Clean Mobility Operations for First-Mile and Last-Mile Public Transit Connections: A Case Study of Doha, Qatar حسب Afnan Fayez Eliyan (19517221)

"…Moreover, adding the carpooling option can significantly decrease the number of relocations operations at a minimal impact on the commuters’ trip performance.…"

Comparative study of structural and superconducting properties of (Cu0.5Tl0.5)Ba2Ca2Cu3O10-δ phase substituted by copper fluoride and thallium fluoride حسب Kamar, A.

"…X-ray diffraction (XRD) revealed that all the samples have a tetragonal symmetry of (Cu0.5Tl0.5)-1223 phase. Additionally, with increasing fluorine content up to x = 0.2 CuF2 and y = 0.1 TlF, the phase fraction and the superconducting transition Tc were enhanced. …"
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Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway حسب Olfa Khalifa (10914452)

"…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …"

National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050 حسب Marie, Ng

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National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050 حسب Marie, Ng

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Global, regional, and national prevalence of adult overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021 حسب Marie, Ng

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Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 حسب Olfa Khalifa (10914452)

"…Concurrently, Ex-4 significantly lowered the expression levels of De novo lipogenesis genes such as SREBP-1, SCD-1and ACC. …"

Part II.: Dissimilar friction stir welding of nickel titanium shape memory alloy to stainless steel – microstructure, mechanical and corrosion behavior حسب Parker West (17268946)

Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis حسب Meritxell Espino‐Guarch (22565774)

"…Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …"

Association Between Three-Months Vitamin D Supplementation and Depressive Symptomatology incidence among Saudi Arabian Adults حسب Khaddaj, Rashel

"…The mean baseline 25(OH)D3 concentration was 16.92±7.23ng/ml in the vitamin D group and 16.44±5.91 ng/ml in the control group (p =0.76). …"
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Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study حسب Houssein H., Ayoub

"…Interventions substantially reduce incidence. Increasing condom use from 10 % to 50 % lowers NG prevalence among FSWs, clients, and their spouses from 12.2 % to 6.4 %, 1.2 % to 0.5 %, and 0.4 % to 0.2 %, respectively. …"
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A critical review on the practical use of lithium cycle as an upfront nitrogen removal technology from natural gas حسب Abdullah Omar (6468326)

"…<p>The increase in energy demand as the world population grows, as well as the competition in the liquefied natural gas (LNG) market, force producers to work hard on developing cost-effective production technologies. …"

Tumor size predicts vascular invasion and histologic grade حسب Abdalla, Eddie

"…The incidence of microscopic vascular invasion increased with tumor size (≤3 cm, 25%; 3.1-5 cm, 40%; 5.1-6.5 cm, 55%; >6.5 cm, 63%) (P < 0.005). …"
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State of Global Financial Crime In-­depth Analysis on GCC Countries حسب Odeh, Layan Mazen

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Higher serum leptin level in women than in nen with type 1 diabetes حسب Azar, Sami T.

"…Leptin levels were also higher in women compared with men (13.5 ± 8.3 ng/mL versus 3.2 ± 1.7 ng/mL; P < 0.05, respectively). …"
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High phosphorus diet mitigates impairments in lipid and glucose metabolism associated with diet-induced obesity in male sprague dawley rats حسب Bassil, Maya

"…Fasting insulin increased significantly (p=0.008) in HF (2.8±0.4ng/ml) vs. control (1.2±0.4ng/ml) but was not different in HFHP group (2.2±0.5ng/ml). …"
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Investigation of the Effect of Exendin-4 on Oleic Acid-Induced Steatosis in HepG2 Cells Using Fourier Transform Infrared Spectroscopy حسب Olfa Khalifa (10914452)

"…Analysis of the Oil Red O staining showed that Ex-4 significantly reduces steatosis. This reduction was confirmed by FTIR analysis, as the phospholipid band (C=O) at 1740 cm−1 in Ex-4 treated cells is significantly decreased compared to steatotic cells. …"

The effects of long-term testosterone treatment on endocrine parameters in hypogonadal men: 12-year data from a prospective controlled registry study حسب Aksam Yassin (14779204)

"…Blood samples were taken at every other visit to measure levels of total T (TT), calculated free T, sex hormone-binding globulin (SHBG), estradiol, luteinizing hormone (LH), follicle-stimulating hormone (FSH), progesterone and prolactin. We observed an increase in TT of 15.5 nmol/L (<i>p</i> < 0.0001), a reduction in SHBG of 10.5 nmol/L (<i>p</i> < 0.0001) and an increase in calculated free T of 383.04 pmol/L (<i>p</i> < 0.0001) over the study period. …"