Search alternatives:
mean decrease » a decrease (Expand Search)
nm decrease » nn decrease (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
mg decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
5 nm » 5 mm (Expand Search), 5 cm (Expand Search)
mean decrease » a decrease (Expand Search)
nm decrease » nn decrease (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
mg decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
5 nm » 5 mm (Expand Search), 5 cm (Expand Search)
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Supplementary Material for: Longitudinal Decrease in Left Ventricular Size with Age: Impact on Mortality and Cardiovascular Hospitalization
Published 2025“…This study investigated clinical characteristics and outcomes associated with longitudinal decreases in LV size in this population. Methods: We analyzed echocardiographic data from 6,232 adults with normal baseline left ventricular end-diastolic diameter (LVEDD), with a mean interval of 4.8 years between baseline and follow-up echocardiograms. …”
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Image_1_Loneliness predicts decreased physical activity in widowed but not married or unmarried individuals.TIF
Published 2024“…</p>Methods<p>We analyzed data from 1,931 older adults without dementia at baseline from the Rush Memory and Aging Project with a mean follow-up of 4.8 years (mean age 79.6 ± 7.7, 74.9% women). …”
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Image1_Decreased mitochondrial respiration associates with frailty in community-dwelling older adults.jpg
Published 2024“…Frail individuals displayed a higher frequency of osteoporosis and depression. The mean age of the participants was 80.2 ± 5.2 years, similar in both groups of men and women. …”
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Mean decrease in accuracy (MDA) of top 15 urine metabolites.
Published 2020“…Urine metabolites with a mean decrease in accuracy ≥ 0.004 in at least one post-treatment time point (2–5) were considered for inclusion in the predictive model.…”
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Metformin lotion decreases TGF-β1 levels in the wounded skin of rats after 10 days of wound healing.
Published 2024Subjects: -
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Spatial representation of mean annual soil loss increase/decrease derived with the different modeling centers (rows) and time steps (columns) with the SSP5-8.5.
Published 2023“…<p>Spatial representation of mean annual soil loss increase/decrease derived with the different modeling centers (rows) and time steps (columns) with the SSP5-8.5.…”
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Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance...
Published 2021“…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo[1,5-<i>a</i>]pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”
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Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance...
Published 2021“…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo[1,5-<i>a</i>]pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”
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Mechlorethamine gel causes epithelium thinning, epithelium-stroma separation, and decreased total stroma cell count.
Published 2025“…C) The total number of cells in the stroma (yellow arrowheads in panel D) decreased after NM exposure. D) Representative images of the stroma in control and NM 5 min. …”
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Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor
Published 2022“…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”
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Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor
Published 2022“…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”