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mean decrease » a decrease (Expand Search)
nm decrease » nn decrease (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
ms decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
50 ms » 50 mg (Expand Search), 50 mm (Expand Search)
5 nm » 5 mm (Expand Search), 5 cm (Expand Search)
mean decrease » a decrease (Expand Search)
nm decrease » nn decrease (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
ms decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
50 ms » 50 mg (Expand Search), 50 mm (Expand Search)
5 nm » 5 mm (Expand Search), 5 cm (Expand Search)
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Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors
Published 2022“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. …”
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Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors
Published 2022“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. …”
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Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors
Published 2022“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. …”
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Dysregulated alternative splicing in DM1 hiNeurons at 10 DPI.
Published 2022“…(d) Scatter plots pertaining to Fig 5c show decreased inclusion of <i>MAPT</i> e2 (top), <i>CSNK1D</i> e9 (bottom left) and <i>MPRIP</i> e9 (bottom right) in DM1 hiNeurons. …”
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The decrease in lactate induced by pyruvate is blocked by inhibition of MAS and of the TCA cycle in HKI/HKII double KD cells.
Published 2023“…This fast inhibitory phase was followed by a sustained one leading to intracellular lactate accumulation (phase 5). We will address the latter phase in a subsequent publication. …”
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Image_3_Chemical Similarity of Co-occurring Trees Decreases With Precipitation and Temperature in North American Forests.jpg
Published 2021“…To test this prediction, we compared patterns of chemical and morphological trait diversity of 140 woody plant species among seven temperate forests in North America representing 16.2°C variation in mean annual temperature (MAT), 2,115 mm variation in mean annual precipitation (MAP), and from 10 to 68 co-occurring species. …”
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Image_2_Chemical Similarity of Co-occurring Trees Decreases With Precipitation and Temperature in North American Forests.jpg
Published 2021“…To test this prediction, we compared patterns of chemical and morphological trait diversity of 140 woody plant species among seven temperate forests in North America representing 16.2°C variation in mean annual temperature (MAT), 2,115 mm variation in mean annual precipitation (MAP), and from 10 to 68 co-occurring species. …”
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Image_1_Chemical Similarity of Co-occurring Trees Decreases With Precipitation and Temperature in North American Forests.jpg
Published 2021“…To test this prediction, we compared patterns of chemical and morphological trait diversity of 140 woody plant species among seven temperate forests in North America representing 16.2°C variation in mean annual temperature (MAT), 2,115 mm variation in mean annual precipitation (MAP), and from 10 to 68 co-occurring species. …”
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Image_4_Chemical Similarity of Co-occurring Trees Decreases With Precipitation and Temperature in North American Forests.jpg
Published 2021“…To test this prediction, we compared patterns of chemical and morphological trait diversity of 140 woody plant species among seven temperate forests in North America representing 16.2°C variation in mean annual temperature (MAT), 2,115 mm variation in mean annual precipitation (MAP), and from 10 to 68 co-occurring species. …”