Deletion of miR132/212 influences synaptic transmission and plasticity in the neocortex. by Judit Remenyi (178669)

“…Whole-cell recording were made at membrane potential of −80 mV in the presence of TTX (1 µM) and picrotoxin (100 µM). Scale bar measures 1 s and 10 pA. B) The superimposition of the average waveform (25 each) of mEPSCs recorded in the fl/fl neuron (black line) and miR-132/212 KO neuron (grey line) shown in A. …”

Characterization of 599 peptide-mediated RNAi responses in oral cancer cells. by Liliana Cantini (453377)

“…(<b>B</b>) Western blot analysis of CIP2A protein knockdown in SCC-25 oral cancer cells 48 hours post-treatment with 599 peptide alone (5 µM) or complexed at a 50∶1 peptide-to-siRNA molar ratio to either siNT (100 nM) or decreasing concentrations of siCIP2A. …”

Immunnohistochemical analysis of CD200R expression in macrophages, the role of CD200-CD200R axis in hMSCs mediated immunosuppression. by Mika Pietilä (332438)

“…Only CD200Me 1, CD200Lo 2 and UCBMSC 2 lines had significant reduction in TNF-α secretion. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0031671#s3" target="_blank">Results</a> are represented as a mean±SD of three independent replicates. …”

Turnover of 4MUG substrate reads out GBA1 activity in human brain lysates in the presence of sodium taurocholate. by Zdenek Berger (440685)

“…A representative experiment is shown in the graphs, a summary of three experiments is depicted in the table (mean ± SEM). …”

Relative Cx43 expression in C6 and F98 cells detected by western blot and RT- PCR analyses. by Zahra Moinfar (2504494)

“…<p>a) F98 cells showed a significant increase and b) C6 cells showed a significant decrease of Cx43 protein expression after treatment with 10 nM or 100 nM E2. c) Transfection of C6 cells with Cx43-cDNA neutralized these effects. d) RT-PCR showed an opposite effect of E2 on Cx43 gene expression in C6 when compared to F98 cells. e) A representative WB showing the increased Cx43 protein expression in F98 cells and the decreased Cx43 expression in C6 cells, after E2 treatment. …”

Ordered effector interplay revealed by <i>trans</i> BENEFIT screening. by Robert J. Cain (272233)

“…Invasion rates after 60 min were compared to wild-type (assigned as 100%). Results are mean±SEM of 4 independent experiments each performed in triplicate. …”

Data Sheet 1_Case Report: Micronized purified flavonoid fraction [Daflon]-induced bradycardia.pdf by Jhennyfer Aline Lima Rodrigues (10278251)

“…During this period, there was a decrease in vein inflammation and varicosity, as shown by magnetic resonance imaging.…”

Both caspase −3 and −9 inhibitors block apoptosis with mitochondrial dysfunction. by Junji Matsuo (187334)

“…*<i>p</i><0.05 vs. the absence of a caspase inhibitor (DMSO). B) A decrease of mitochondrial membrane integrity was observed in HEp-2 cells incubated with <i>Protochlamydia</i>. …”

52-Week Efficacy and Safety of Telbivudine with Conditional Tenofovir Intensification at Week 24 in HBeAg-Positive Chronic Hepatitis B by Teerha Piratvisuth (279131)

“…Myalgia was more common in the monotherapy group (19% versus 7%). No decrease in the mean glomerular filtration rate occurred in either treatment group at Week 52.…”

Isolation and characterization of brain derived EVs. by Sowmya V. Yelamanchili (482686)

“…EVs show a size range from 100–150 nm. Scale bar = 100 nm. …”

Figure 3 by Sankaralingam Prabhu (335023)

“…The excitation wavelength was 295 nm. The excitation and the emission band passes were set at 2.5 nm. …”

Image_2_Light intensity changes and UVB radiation affect peridinin content and antioxidant activity in the Cassiopea andromeda holobiont.jpeg by Holger Kühnhold (6499133)

“…</p>Materials and Methods<p>Indoor bred C. andromeda specimens were exposed to five different PAR intensities (50, 100, 200, 400 and 800 µmol photons m⁻² s⁻¹) and a combined treatment of narrow-band UVB (λ = 285 ± 10 nm) radiation and intermediate (200 µmol photons m⁻² s⁻¹) PAR intensity over a period of four weeks. …”

Image_1_Light intensity changes and UVB radiation affect peridinin content and antioxidant activity in the Cassiopea andromeda holobiont.jpeg by Holger Kühnhold (6499133)

“…</p>Materials and Methods<p>Indoor bred C. andromeda specimens were exposed to five different PAR intensities (50, 100, 200, 400 and 800 µmol photons m⁻² s⁻¹) and a combined treatment of narrow-band UVB (λ = 285 ± 10 nm) radiation and intermediate (200 µmol photons m⁻² s⁻¹) PAR intensity over a period of four weeks. …”

Insolubilization of HRD1 and SEL1L proteins by oxidative stress-inducing agents. by Ryo Saito (519632)

“…Data are normalized to the amount of β-actin; results are expressed as a fold increase compared with the non-treated control (mean ± SEM; <i>n</i> = 6). …”

Analysis of tubular proliferation and atrophy in neonatal mice following UUO. by Maja Wyczanska (17468479)

“…Quantification of Ki67-positive tubular cells in UUO-kidneys (C) shows a decrease following UUO without significant differences between WT and <i>Tlr2</i>^<i>-/-</i>. …”

Line diagrams of the development of individual values of perfusion MRI parameters of tumor microcirculation in the therapy and the control group. by Ralf S. Eschbach (691194)

“…<p><b>a.</b> Note the significant (p<0.01) unidirectional decline of tumor plasma flow (mL/100mL/min) in all tumors under regorafenib therapy and a significant unidirectional increase of tumor perfusion (p<0.03) in untreated control group between baseline (day0) and follow-up (day 7). …”

Dose and time dependency of BaP1 effects on type IV collagen from vascular BM on isolated mouse cremaster muscle. by Cristina Herrera (576490)

“…The images show a decrease in fluorescence intensity for type IV collagen in BM of capillaries of treated tissues as compared to control, whereas no significant reduction was observed in arterioles and PCV. …”

Nuclear Quantum Effects in Sodium Hydroxide Solutions from Neural Network Molecular Dynamics Simulations by Matti Hellström (1886893)

“…Moreover, NQEs significantly lower the proton transfer barriers, thus increasing the proton transfer rates, resulting in an increase of the diffusion coefficient in particular of OH^–, as well as a decrease of the mean residence time of molecules in the first hydration shell around Na⁺ at high NaOH concentrations.…”

Rescue of OCSt-KO BMMC by lentiviral transduction. by Hanna Witwicka (741272)

“…</b> Quantitation of resorbed area shows a roughly 3.5-fold decrease of resorption activity in KO <i>vs</i>. …”

Gemcitabine and ATR inhibitor synergism and effects on the cell cycle and DNA damage in CH22 and U-CH17PII (Batch 2) by Chordoma Foundation (4391989)

“…</p><p><br></p><p dir="ltr">The following panels were treated according to panel A. The concentrations of gemcitabine and elimusertib used for CH22 were 5nM and 100nM, respectively, with those doses combined in the combination. …”