Effect of iron deficiency on cell proliferation and cell cycle. by Dongqiang Song (419760)

“…The c-kit⁺ CSCs were treated with/without DFO (100 µM) or the complex of DFO (100 µM) and Fe(III) (0.5 mM) for 48h. …”

TGM2 inhibition by siRNA treatment induces cell apoptosis. by Yin-Cheng Huang (633119)

“…Meningioma cells treated with <i>TGM2</i> siRNA exhibited reduced TGM2 expression in a dose-dependent manner (>80% in 5 nM siRNA). (B) Cell viability assessed using the MTT assay showed 30% decrease of cell survival following 5 nM siRNA exposure. …”

FRET analysis of mNdK-catalyzed cleavage of single strand DNA (FP1T) by Praveen Kumar (8242)

“…Arrow indicates decrease in 575 nm after the specified times (1 and 18 h) following addition of mNdK (0.25 nM) to P1 (40 nM). …”

Preincubation with papaverine inhibits norepinephrine (NE) induced contractions in human saphenous vein. by Kyle M. Hocking (402156)

“…Panel B: Cumulative data obtained when the force was converted to stress and decrease in stress was converted to a percentage of the maximal initial KCl contraction which was set as 100%. …”

QTLs for yield and yield-components in F_{2: 3} and F_{2: 4} populations identified using composite interval mapping. by Qingzhi Liang (789537)

“…<p>* Common QTLs identified in the two generations</p><p>^a Additive effects; positive values of the additive effects indicate increase of traits from alleles of GX1135; negative values of the additive effects indicate decrease of traits from alleles of GX100-2</p><p>^b Dominance effects; positive values of the dominance effect indicate that heterozygotes have higher phenotypic values than the respective means of two homozygotes, and negative values indicate that heterozygotes have lower values than the means of the two homozygotes</p><p>^c Var%, phenotypic variation explained by a single QTL</p><p>QTLs for yield and yield-components in F_{2: 3} and F_{2: 4} populations identified using composite interval mapping.…”

Plant-derived phenolic acids inhibit protein oxidation in isolated human LDL to varying degrees. by Arantza Soler-Cantero (141469)

“…All phenols were tested at three concentrations (5 µM, 50 µM and 100 µM). LDL and Cu⁺⁺ incubated LDL were used as control of native and oxidized LDL. …”

Parasitemia titration results. by Paul Lebel (11250722)

“…<p>Logscale plots a-b,d-f contain shaded regions corresponding to nominal mean parasitemia plus or minus one standard deviation of the underlying Poisson distribution when counting N total cells, where N is varied from 100 up to 100,000 in roughly 3× increments. …”

Mechanisms involved in Sag-induced apoptosis. by Juliana Mundiñano (306020)

“…Data are expressed as the mean ± SD. *p<0.05. (E) Caspase-8 inhibitor decreases the loss of Δψm induced by SEB. …”

Modest Reduction of Na⁺ Current Induces a Frequency-Dependent Output-Mode Transition from Bursting to Single Spiking by Donald C Cooper (71501)

“…<div><p>(A) The number of bursts in response to a train of five suprathreshold sEPSC currents injections at 2 and 5 Hz delivered every 20 sec before, during (red), and after bath application of 1 nM TTX. …”

Alteration of the steady state equilibrium pupillary reflex response following pre-exposure with monochromatic lights. by Ludovic S. Mure (262696)

“…<p>(A) Representative responses of a subject during the 5 minutes of 480 nm monochromatic light (test stimulation, 1e12 photons/cm²/sec, 5 min duration) after pre-exposures to 5 minutes to an adapting 620 nm (red line), 480 nm (blue line) or no light (“black”, green line) compared to the normalized dark adapted reference response (black line; see temporal sequence of exposure above, further details in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0005991#s2" target="_blank">Methods</a>). …”

Effects of diabetes mellitus and systemic arterial hypertension on elderly patients' hearing, by Laurie Penha Rolim (6073727)

“…ANOVA and Kruskal-Wallis statistical tests were used, with a significance level set at 0.05. Results: When comparing the mean annual increase in the auditory thresholds of the A1 with the A2 assessment, considering each study group and its respective control, it can be observed that there was no statistically significant difference for any of the frequencies for the diabetes mellitus group; for the systemic arterial hypertension group, significant differences were observed after 4 kHz. …”

Stable inducible expression of various GFP-coilin proteins with endogenous coilin knockdown. by Zunamys I. Carrero (342815)

“…Rescue indicates that the induced protein increased proliferation in the coilin knockdown background, whereas decrease means the induced protein decreased proliferation rates lower than that found with coilin knockdown alone. …”

Senescence is induced by either macrophages or NO• in primary normal human fibroblasts in culture. by Jane J. Sohn (138016)

“…(B) The NO• synthase inhibitor L-NAME reduces diffused NO• in media of cocultures comprised of normal human fibroblasts (WI38 or MRC5) and macrophages (ANA-1). 100 µl of media from three separate cocultures was aliquoted with 100 µL of 5 µM of DAF in 96-well plates. …”

Monitoring ciliary entry and exit of Smo-mEos2 in KAAD-cyclopamine-treated cells. by Jynho Kim (614435)

“…Asterisks show statistically significant differences (Smo-mEos2^N recovery, P = 0.0059; Smo-mEos2^P decrease, P = 0.86). Error bars show SD, n = 5.</p>…”

Monitoring ciliary entry and exit of Smo-mEos2 in CBA-treated cells. by Jynho Kim (614435)

“…Asterisks show statistically significant differences (Smo-mEos2^N recover, P = 0.00059; Smo-mEos2^P decrease, P = 0.0035). Error bars show SD, n = 5.</p>…”

PRE, W3, and W6 VL biopsy contractile protein per muscle fiber assessed through phalloidin-AF488 staining. by Cody T. Haun (4183900)

“…This metric was not significantly altered throughout the intervention (panel a). Phalloidin pixel intensity per fiber per μm², which represents actin content corrected for fCSA, demonstrated numerical but non-significant decreases from PRE to W3 and W6 (panel b), although the removal of subject 17 (statistical outlier) indicated a significant decrease occurred from PRE to W6. …”

Glyphosate Resistance Affect the Physiological Quality of Conyza bonariensis seeds by C. PIASECKI (5054501)

“…Seed analyses were performed in a completely randomized design with ten replications of 100 seeds each (1,000 seeds per biotype). …”

Interplay of basolateral K⁺ channels and the Na⁺/K⁺-ATPase. by Alexandra Erb (588278)

“…<b>B</b>) After permeabilisation with nystatin, lidocaine (1 mM) was applied to the basolateral bath. This resulted in a decrease of the I_SC from 17.20±2.58 µA/cm² to 12.00±1.67 µA/cm² (n = 5, N = 5, p≤0.05). …”

HOXA2 control of target enhancers. by Laure Bridoux (481118)

“…Co-translation of HOXA2 with PBX/MEIS gives rise to a stronger trimeric complex relative to HOXA3 and, accordingly, to a decrease in PBX-MEIS binding as a dimer (black arrow; see also <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009162#pgen.1009162.s003" target="_blank">S3G Fig</a> for quantification). …”

Excitation-Transcription (E-T) coupling is altered in dystrophic muscle fibers. by Denisse Valladares (489234)

“…<p>(A) In triad fractions obtained from normal and dystrophic muscles we observed a decrease in the expression of Cav1.1 (antibody against α1 s subunit) and an increase in the expression of Panx1, P2Y2 and P2Y1 in dystrophic compared to normal (n = 4). …”