Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms by Farman M. Abbasi (22318766)

Subjects:

Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms by Farman M. Abbasi (22318766)

Subjects:

Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms by Farman M. Abbasi (22318766)

Subjects:

FA decrease in 5STS impaired participants. by Charlotte Bernard (433013)

The specific TH activity of the cell lysates after transfection with wild-type TH, mutant TH^A304V, and TH^R453H. by Zhan-fang Sun (624794)

“…<p>Compared with the wild-type, the specific TH activity with the mutant TH^A304V and TH^R453H were both significantly decreased (<i>P</i><0.05). …”

A. We randomly selected 20 mutually exclusive groups of protein complexes that contained exactly five subunits; we mapped the corresponding gene pairs to SINaTRA scores, and plotte... by Alexandra Jacunski (5665486)

“…A SINaTRA cutoff of 0.95 has approximately half of its pairs associated with the same complex; however, a decrease in the cutoff shifts this balance. …”

Decreased levels of PRMT1 alters BRCA1 promoter binding <i>in vivo.</i> by Irene Guendel (173419)

Treatment with rSFRP4 results in decreased migration and increased adhesion of ovarian cancer cells. by Caroline E. Ford (289563)

ATRA decreases the binding of Nrf2 to ARE sequences in the promoter regions of HO-1, GCLM and x-CT in BTZ-treated cells. by A. L. Furfaro (2587792)

The effect of bicarbonate on secretagogue stimulated zymogen activation decreased by PKA inhibition using myristolated PKI. by Thomas R. Kolodecik (297507)

The effect of bicarbonate on secretagogue stimulated zymogen activation is decreased by PKA inhibition using H89. by Thomas R. Kolodecik (297507)

NAC treatment decreases myeloid differentiation of <i>Ptpn11</i> GOF mutant cells. by Dan Xu (138152)

BA decreases mitochondrial membrane potential and superoxide production after one day of cell culture. by Bandik Föh (602419)

“…<p>(A) Representative contour plots of MT-Green/TMRE-stained B cells after incubation with 0.5 mM BA for 1 day. …”

Tan IIA decreased LPS-induced NF-κB activity in HSC-T6 cells. by Ya-Wei Liu (606320)

DataSheet_1_Imiquimod Boosts Interferon Response, and Decreases ACE2 and Pro-Inflammatory Response of Human Bronchial Epithelium in Asthma.pdf by Juan José Nieto-Fontarigo (11800142)

“…Background<p>Both anti-viral and anti-inflammatory bronchial effects are warranted to treat viral infections in asthma. We sought to investigate if imiquimod, a TLR7 agonist, exhibits such dual actions in ex vivo cultured human bronchial epithelial cells (HBECs), targets for SARS-CoV-2 infectivity.…”

Knockdown of PABPC1 with siRNA decreases PSA luciferase activity and PSA protein levels. by Kurtis Eisermann (95302)

Resistance to Pap-A correlates with decreases in PS. by Chelsi D. Cassilly (2793433)

Combined decitabine and Taxol decreases MCF-7/Taxol cells proliferation and can improve their chemosensitivity. by Weihua Gong (471435)

Supplementary Material for: Longitudinal Decrease in Left Ventricular Size with Age: Impact on Mortality and Cardiovascular Hospitalization by figshare admin karger (2628495)

“…This study investigated clinical characteristics and outcomes associated with longitudinal decreases in LV size in this population. Methods: We analyzed echocardiographic data from 6,232 adults with normal baseline left ventricular end-diastolic diameter (LVEDD), with a mean interval of 4.8 years between baseline and follow-up echocardiograms. …”

SKO mice demonstrate increased cholesterol efflux in whole skin, and decreased cholesterol levels in plasma. by Sabrina N. Dumas (5474456)