CDK5 knockdown increases TP53 and p27^Kip1 protein half-lives, increases nuclear localization of the two proteins, decreases p27^Kip1 p-T187 phosphorylation and... by Shu Zhang (22238)

“…Cytoplasmic (CE) and nuclear (NE) extracts were analyzed by immunoblotting. (<b>C</b>) CDK5 siRNA decreased the phosphorylation of p27Kip1 at T187. …”

Retinoic acid decreases intracellular K⁺ in pectoral fin buds via transcriptional activation of the calcineurin inhibitor <i>rcan2</i>. by Xiaowen Jiang (8291814)

The MMP was decreased by incubation with CytoD or LatB. by Dong-Hee Yang (566631)

“…An MMP collapse was detected as a decrease in the percentage of cells with high red fluorescence intensity. …”

Silencing of dynamin II decreases apoE secretion. by Maaike Kockx (154125)

Fig 5 - by Raheleh Farahzadi (3860311)

Inhibition of VEGF-A gene synthesis decreased ranibizumab and aflibercept mediated CCL2 CCL5, and CX3CL1 mRNA and protein levels in HCAECs. by Clare Arnott (2557705)

Changes in neuronal morphology after 150 nM sAPP-Fc added to 5DIV neurons. by Stéphanie Chasseigneaux (231744)

“…<p>Morphometric analysis 96 hours after the addition of 150 nM sAPP-Fc to 5DIV neurons shows that: (<b>A</b>) sAPP-Fc induces a significant decrease of primary dendrite number (control (Ctrl) vs sAPP-Fc: p<0.0276). …”

Stable overexpression of PFKFB3-5 in HEK-293 and U87 cells leads to decreased cell viability and proliferation while leaving transcriptional profile of PFKFB3-1 and -11 unaltered. by Ulli Heydasch (11091062)

HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching. by Michael Anthony Ruiz (726055)

“…However, transfection of SUZ12 siRNA significantly reduced endothelial branching compared to HG+control siRNA. [NG+control siRNA = 5mM D-glucose + 100nM control siRNA, HG+control siRNA = 25mM D-glucose + 100nM control siRNA, HG+EZH2 siRNA = 25mM D-glucose + 100nM EZH2 siRNA, HG+SUZ12 siRNA = 25mM + 100nM SUZ12 siRNA; identical letters represent groups that are not significantly different; p < 0.05; n = 6; data expressed as mean ± SEM, normalized to U6 or β-actin and expressed as a fold change of NG+control siRNA].…”

A Yoga Strengthening Program Designed to Minimize the Knee Adduction Moment for Women with Knee Osteoarthritis: A Proof-Of-Principle Cohort Study by Elora C. Brenneman (795723)

“…Participants experienced reduced pain (mean improvement 10.1–20.1 normalized to 100; p<0.001), increased knee extensor strength (mean improvement 0.01 Nm/kg; p = 0.004), and increased flexor strength (mean improvement 0.01 Nm/kg; p = 0.001) at follow-up compared to baseline. …”

Data_Sheet_5_Chemical Similarity of Co-occurring Trees Decreases With Precipitation and Temperature in North American Forests.CSV by Brian E. Sedio (10875330)

“…To test this prediction, we compared patterns of chemical and morphological trait diversity of 140 woody plant species among seven temperate forests in North America representing 16.2°C variation in mean annual temperature (MAT), 2,115 mm variation in mean annual precipitation (MAP), and from 10 to 68 co-occurring species. …”

Missense Variant in MAPK Inactivator <i>PTPN5</i> Is Associated with Decreased Severity of Post-Burn Hypertrophic Scarring by Ravi F. Sood (263139)

“…</p><p>Conclusions</p><p>We report <i>PTPN5</i> as a novel genetic locus associated with HTS severity. …”

Decreased production of antiviral factors in patients infected with SARS-CoV-2 due to reduced TLR7 expression by Julia Cataldo Lima (22811497)

“…</p> <p>To investigate this, we analyzed the expression of interferon-stimulated genes (ISGs) in 48 SARS-CoV-2-infected patients using real-time polymerase chain reaction (RT-qPCR) and assessed toll-like receptor (TLR7) expression in blood cells via flow cytometry.…”

Acetylcholine-induced NO- and EDHF-mediated relaxations decrease with increasing age. by Noureddine Idris Khodja (331400)

Decrease of actin velocity when passing confined TCR clusters. by Cheng-han Yu (244912)

NETs decrease <i>T</i>. <i>cruzi</i> infectivity. by Daniel Sousa-Rocha (802734)

Detection of epistasis is confined in a time window whose width is controlled by the mean selection coefficient. by Gabriele Pedruzzi (5753792)

VEGFR2/VEGF-A ligand binding decreased ranibizumab and aflibercept mediated CCL2, CCL5, and CX3CL1 mRNA and protein levels in HCAECs. by Clare Arnott (2557705)

Vasopressin decreases EPSPs in CA2 after LTP induction. by Magda Chafai (295116)

“…Vasopressin (AVP 10 nM; 1 min) applied during LTP transiently decreased the EPSP amplitude. …”

Su(H) and RBPJ AOS variants decrease DNA binding. by Ellen K. Gagliani (11478756)