Alp5a and Alp5b are not individually required for asexual blood stage propagation, but simultaneously, they are indispensable for parasite viability. by Aastha Varshney (22601181)

“…<p><b>(A)</b> Parasites transfected with constructs targeting Alp5a and Alp5b, tagged with mCherry and GFP respectively, predominantly gave rise to single knockout populations expressing only one of the two fluorophores. …”

Ba₂NaClP₂O₇: Unprecedented Phase Matchability Induced by Symmetry Breaking and Its Unique Fresnoite-Type Structure by Jie Chen (5892)

“…Herein, we report a unique Ba₂NaClP₂O₇ representing the first phase-matchable example of the fresnoite family, which exhibits excellent NLO properties, including short absorption edge (<176 nm, ca. 7.0 eV), strong second-harmonic generations at the incident lasers of 850–1110 nm (obv. 0.9–1.3 × KDP; cal. …”

miR-214 decreased the number of viable cells and induced apoptosis in HSA cell lines. by Kazuki Heishima (791938)

“…<p>(A) Cell viability was assessed by performing the MTT assay. miR-214-transfection decreased the number of viable cells in HSA cell lines and that of control EC. …”

miR-200b reverses EMT and decreases invasion and metastasis by PC3 cells. by LaTanya V. Williams (504683)

Effect sizes (if > 0.5) for the comparison of increasing load vs. decreasing load for the multifidus muscle. by Christoph Anders (4068499)

Effect sizes (if > 0.5) for the comparison of increasing load vs. decreasing load for the longissimus muscle. by Christoph Anders (4068499)

Hydroxyl Defects in LiFePO₄ Cathode Material: DFT+<i>U</i> and an Experimental Study by Dmitry A. Aksyonov (4918594)

“…The P occupancy decrease is explained by the formation of hydrogarnet-like P/4H and P/5H defects, which have the lowest formation energies among all considered OH defects. …”

HLA-C expression levels increase and exon 1 skipping decreases as NK cells mature. by Hongchuan Li (375905)

Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i>_i = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i>_i = 0.436 nM) substitution of the <i>N</i>⁴-benzyloxy group decreased <i>K</i>_i by ∼20-fold. …”

Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i>_i = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i>_i = 0.436 nM) substitution of the <i>N</i>⁴-benzyloxy group decreased <i>K</i>_i by ∼20-fold. …”

Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i>_i = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i>_i = 0.436 nM) substitution of the <i>N</i>⁴-benzyloxy group decreased <i>K</i>_i by ∼20-fold. …”

TreeView Images of Examples of Great Ape and HLS Gene Copy Number Increases and Decreases by Andrew Fortna (4005)

“…Estimates of the time at which indicated branch points occurred during hominoid evolution are derived from <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0020207#pbio-0020207-Chen1" target="_blank">Chen and Li (2001)</a>.…”

Origin firing efficiency is decreased for all replication origins when Pol α levels are reduced. by Sarina Y. Porcella (8811746)

UV dose responses by sequential UV-A followed by UV-C exposure for (A) MS2 and (B) E. coli K-12 in PBS and NOM. by Daniel Ma (12698752)

Inducible expression of <i>EVI1</i> decreases the sensitivity of HL-60 cells to daunorubicin. by Anna Rommer (241040)

Schematic of the reduced model. by Jason Chen (15937)

Subjects:

Fibrin concentration of 10,000 simulations compared to experimental data of blood clotting over collagen/ TF under venous flow rate. by Jason Chen (15937)

Subjects:

The rate of increasing trend in the percentage of Nova Scotia Seniors' Pharmacare Program beneficiaries dispensed rosuvastatin decreased significantly upon the availability of gene... by Laura V. Minard (349145)

BCL2 antiapoptotic protein exhibits heterogeneous expression in Ba/F3 EML4-ALK^mutants. by Richard Junior Zapata Dongo (17912565)

Albumin Decrease Is Associated with Spontaneous Preterm Delivery within 48 h in Women with Threatened Preterm Labor by Yujing J. Heng (1696339)

“…SWATH methodology quantified 258 proteins (using ≥2 peptides) and 5 proteins (ALBU, ANXA6, HNRPK, HSP90A, and PDIA1) were differentially expressed (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). iTRAQ workflow identified 765 proteins; 354 proteins were quantified and 14 proteins (MIF, UBIQ, HXK3, ALBU, HNRPD, ST1A2, RS15A, RAP1B, CAN1, IQGA2, ST1A1, COX5A, ADDA, and UBQL1) were significantly different between the two groups of women (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). …”