Decreased Brain Levels of Vitamin B12 in Aging, Autism and Schizophrenia by Yiting Zhang (391974)

“…Vitamin B₁₂ (cobalamin, Cbl) exists in multiple forms, including methylcobalamin (MeCbl) and adenosylcobalamin (AdoCbl), serving as cofactors for MS and methylmalonylCoA mutase, respectively. We measured levels of five Cbl species in postmortem human frontal cortex of 43 control subjects, from 19 weeks of fetal development through 80 years of age, and 12 autistic and 9 schizophrenic subjects. …”

Aged blood factors decrease cellular responses associated with delayed gingival wound repair by María Paz Saldías (4430032)

“…<div><p>Aging is a gradual biological process characterized by a decrease in cell and organism functions. …”

Due to frequency masking, the auditory responses to both standard and target tones decrease with narrower notches (responses to standard tone shown in Figures 4 and 5). by Jaakko Kauramäki (303223)

Hematopoietic stem/progenitor cells decreases in the fetal liver of <i>CALM</i>^−/− mice and their colony forming activities are impaired. by Shinya Rai (332061)

The decrease in <i>Brucella</i> AHLs activity during <i>in vitro</i> growth is linked to <i>aibP</i> expression. by Matthieu Terwagne (495790)

Decreased survival of mutants upon treatment with a bacteriostatic antibiotic chloramphenicol by Lisa K Smith (32955)

SPL treatment decreases diabetes-induced co-immunoprecipitation (co-IP) of cldn-4 and -8. by Eduardo Molina-Jijón (4020464)

“…Also, increased co-IP of cldn-8 with cldn-4 was found under diabetic condition and SPL decreased this interaction (C), densitometric analysis show that these changes were significant (D) (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0177362#pone.0177362.s005" target="_blank">S5 Fig</a>). …”

Gating properties of <i>CACNA1I</i> variants with pooled WT data. by Yousra El Ghaleb (22075892)

Subjects:

PB2 variants D605A and V606A do not affect the secondary structures of the PB2 ‘627’ domain. by Ho-Pan Hsia (4768638)

The detection of red (652–669 nm) and green (533–550 nm) fluorescence from yellow-green and violet laser excitation in control and H₂O₂-treated <i>M</i>. <i>a... by Emma T. Brentjens (17295999)

Subjects:

Bortezomib in combination with the PLK1 inhibitor BI 2536 induces a significant downregulation of the total levels and phosphorylation of Bcr-Abl, a decrease of downstream phosphorylated STAT5 and a caspase-dependent cell death in TKIs-resistant and –sensitive K562 cell lines. by Octavian Bucur (470431)

“…The combined treatment resulted in a marked decrease of the total levels of Bcr-Abl, which correlates with a decrease in the phosphorylation of the downstream STAT5 protein, in both K562 and K562-R cells. β-Actin was used as an internal loading control. …”

JBPOS0101 decreased Amyloid Beta (Aβ) aggregates in the cortex and hippocampal regions in 5xFAD mouse brains. by Jihoon Jeong (4852690)

CDK5 knockdown increases TP53 and p27^Kip1 protein half-lives, increases nuclear localization of the two proteins, decreases p27^Kip1 p-T187 phosphorylation and induces p21^Cip1 in a TP53-dependent manner. by Shu Zhang (22238)

“…<p>(<b>A</b>) Transfection with CDK5 siRNA increased the half-life of p53 and p27^Kip1 protein. …”

Glucagon resistance and decreased susceptibility to diabetes in a model of chronic hyperglucagonemia by Nadejda Bozadjieva Kramer (9657179)

Removal of the A-B linker did not decrease PIP₂ affinity. <i>A.-</i> by Paloma Aivar (124885)

Increased amount of phosphorylated proinflammatory osteopontin in rheumatoid arthritis synovia is associated to decreased tartrate-resistant acid phosphatase 5B/5A ratio by Jani Luukkonen (4339744)

“…The TRAcP 5B/5A ratio was decreased in RA and correlated negatively with the amount of phospho-OPN (p<0.05). …”

Decreased neutrophil levels in HIF^C mice correlates to decreased production of CXCL1 and not migration defects. by Kelly M. Shepardson (404375)

Inhibition of SKI-1/S1P enzymatic activity using PF-429242 impairs activation of the SREBP pathway and correlates with a dramatic decrease in lipid droplet number and area. by Anastasia Hyrina (3860455)

At E9.5 Actb^−/− neural crest cells show a significant decrease of cadherin-11 expression. by Davina Tondeleir (426905)

“…We only observed a significant reduction of cadherin-11 intensities in Actb^−/− neural crest cells at E9.5. …”

H-MSCs^WT reduced infarct size and collagen I expression 7 days post-MI. by Panpan Chen (307628)