Showing 161 - 180 results of 17,845 for search '(( 5 nm decrease ) OR ( 50 ((((n decrease) OR (a decrease))) OR (nn decrease)) ))', query time: 0.59s Refine Results
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    Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

    Published 2021
    “…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC<sub>50</sub> value of 6 nM). …”
  4. 164

    Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

    Published 2021
    “…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC<sub>50</sub> value of 6 nM). …”
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    Cinacalcet administered early in the inactive phase markedly decrease parathyroid Ki-67 index. by Søren Egstrand (10906087)

    Published 2025
    “…<p>(A) Ki-67 expression in parathyroid glands of rats with CKD-induced sHPT treated with Cinacalcet either early in the inactive light phase (<i>Cina1</i>; N = 10) or early in the active dark phase (<i>Cina2</i>; N = 9) compared to untreated rats with sHPT investigated at similar time points (<i>PNX1</i>; N = 7 and <i>PNX2</i>; N = 7, respective) and to normal rats investigated at similar time points (<i>ctrl1</i>; N = 9 and <i>ctrl2</i>; N = 7, respective). …”
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