Neurostatin down-regulates GFAP expression in astrocytes. by Bhagyalaxmi S. Ganesh (353895)

“…<p>C57BL/6 mice (n = 6) were treated by intravitreal injection of PBS, KA (10 nM), or KA plus Neurostatin (5 mM). At 24, 48 and 72 h after injection, glial cell activation was observed by immunostaining of retinal flat mounts with antibodies against GFAP (top panel) or retinal cross sections (lower panel) with antibodies against GFAP (green fluorescence) and vimentin (red fluorescence). …”

Neurostatin attenuates KA-induced ganglion cell loss. by Bhagyalaxmi S. Ganesh (353895)

“…<p>C57BL/6 mice were treated by intravitreal injection of PBS, KA (10 nM), Neurostatin (5 mM), or KA plus Neurostatin. …”

Simultaneous determination of invasion and cytotoxicity. by Nikki A. Evensen (495977)

“…<p>HT1080 cells expressing GFP were assembled in the 3-D invasion assay in the presence of (A) DMSO, (B) anti-β1 integrin antibody (5 μg/ml), (C) staurosporine (STS) (500 nM), or (D) paclitaxel (Taxol, 1 μM) for 18 hours. …”

Gene expression variation in tumor and non-malignant samples. by Kun Yu (50987)

“…Equal numbers of tumor and control samples (50) were randomly selected from the training set to generate a cumulative distribution graph depicting the genome-wide distribution of CVs across tumors (red line) and controls (green line). …”

The type III Interferon response is host protective and epithelial cell intrinsic. by Alexis R. Gibson (12563046)

“…All mice were infected with mouse adapted <i>C</i>. <i>parvum</i>. (A) C57/BL6 (BL6) mice were infected with 50,000 <i>C</i>. …”

Superior Hard but Quickly Reversible Si–O–Si Network Enables Scalable Fabrication of Transparent, Self-Healing, Robust, and Programmable Multifunctional Nanocomposite Coatings by Yi Hou (148620)

“…The highly cross-linked continuous network endows the coating with a hardness (<i>H</i> = 0.83 GPa) higher than those of most polymers (<i>H</i> < 0.3 GPa), while the uniformly dispersed micelles decrease the Young’s modulus (<i>E</i> = 5.89 GPa) to a value as low as that of common plastics, resulting in excellent hardness and flexibility, with an <i>H</i>/<i>E</i> of 14.1% and an elastic recovery rate (<i>W</i>_e) of 86.3%. …”

Superior Hard but Quickly Reversible Si–O–Si Network Enables Scalable Fabrication of Transparent, Self-Healing, Robust, and Programmable Multifunctional Nanocomposite Coatings by Yi Hou (148620)

“…The highly cross-linked continuous network endows the coating with a hardness (<i>H</i> = 0.83 GPa) higher than those of most polymers (<i>H</i> < 0.3 GPa), while the uniformly dispersed micelles decrease the Young’s modulus (<i>E</i> = 5.89 GPa) to a value as low as that of common plastics, resulting in excellent hardness and flexibility, with an <i>H</i>/<i>E</i> of 14.1% and an elastic recovery rate (<i>W</i>_e) of 86.3%. …”

Assessment of quality of life in type II diabetic patients using the modified diabetes quality of life (MDQoL)-17 questionnaire by Vivek Bhanubhai Prajapati (12848338)

“…As the number of complications increased, there was a decrease in the QoL. The presence of comorbidity also decreased the QoL. …”

Splenectomy Associated Changes in IgM Memory B Cells in an Adult Spleen Registry Cohort by Paul U. Cameron (210950)

“…Changes of asplenia in routine blood films including presence of Howell-Jolly bodies (HJB), occurred early (median 25 days) and splenectomy associated thrombocytosis and lymphocytosis peaked by 50 days. There was a more gradual decrease in IgM memory B cells reaching a stable level within 6 months after splenectomy. …”

Source data file. by Laura Mora-Bitria (20477525)

“…We studied Type 1 diabetes (T1D) as a paradigmatic example of autoimmunity. In T1D, variation in the Human Leucocyte Antigen (HLA) genes explains up to 50% of the genetic risk, indicating that T cells have a major role in T1D etiopathogenesis. …”

Superior Hard but Quickly Reversible Si–O–Si Network Enables Scalable Fabrication of Transparent, Self-Healing, Robust, and Programmable Multifunctional Nanocomposite Coatings by Yi Hou (148620)

“…The highly cross-linked continuous network endows the coating with a hardness (<i>H</i> = 0.83 GPa) higher than those of most polymers (<i>H</i> < 0.3 GPa), while the uniformly dispersed micelles decrease the Young’s modulus (<i>E</i> = 5.89 GPa) to a value as low as that of common plastics, resulting in excellent hardness and flexibility, with an <i>H</i>/<i>E</i> of 14.1% and an elastic recovery rate (<i>W</i>_e) of 86.3%. …”

Superior Hard but Quickly Reversible Si–O–Si Network Enables Scalable Fabrication of Transparent, Self-Healing, Robust, and Programmable Multifunctional Nanocomposite Coatings by Yi Hou (148620)

“…The highly cross-linked continuous network endows the coating with a hardness (<i>H</i> = 0.83 GPa) higher than those of most polymers (<i>H</i> < 0.3 GPa), while the uniformly dispersed micelles decrease the Young’s modulus (<i>E</i> = 5.89 GPa) to a value as low as that of common plastics, resulting in excellent hardness and flexibility, with an <i>H</i>/<i>E</i> of 14.1% and an elastic recovery rate (<i>W</i>_e) of 86.3%. …”

Superior Hard but Quickly Reversible Si–O–Si Network Enables Scalable Fabrication of Transparent, Self-Healing, Robust, and Programmable Multifunctional Nanocomposite Coatings by Yi Hou (148620)

“…The highly cross-linked continuous network endows the coating with a hardness (<i>H</i> = 0.83 GPa) higher than those of most polymers (<i>H</i> < 0.3 GPa), while the uniformly dispersed micelles decrease the Young’s modulus (<i>E</i> = 5.89 GPa) to a value as low as that of common plastics, resulting in excellent hardness and flexibility, with an <i>H</i>/<i>E</i> of 14.1% and an elastic recovery rate (<i>W</i>_e) of 86.3%. …”

Image_1_Poly I:C Activated Microglia Disrupt Perineuronal Nets and Modulate Synaptic Balance in Primary Hippocampal Neurons in vitro.TIF by David Wegrzyn (10180829)

“…Interestingly, immunocytochemical staining of the PNN component Aggrecan revealed a clear disruption of PNNs accompanied by a significant increase of glutamatergic and a decrease of γ-aminobutyric acid-(GABA)ergic synapse numbers on PNN wearing neurons. …”

Superior Hard but Quickly Reversible Si–O–Si Network Enables Scalable Fabrication of Transparent, Self-Healing, Robust, and Programmable Multifunctional Nanocomposite Coatings by Yi Hou (148620)

“…The highly cross-linked continuous network endows the coating with a hardness (<i>H</i> = 0.83 GPa) higher than those of most polymers (<i>H</i> < 0.3 GPa), while the uniformly dispersed micelles decrease the Young’s modulus (<i>E</i> = 5.89 GPa) to a value as low as that of common plastics, resulting in excellent hardness and flexibility, with an <i>H</i>/<i>E</i> of 14.1% and an elastic recovery rate (<i>W</i>_e) of 86.3%. …”

Superior Hard but Quickly Reversible Si–O–Si Network Enables Scalable Fabrication of Transparent, Self-Healing, Robust, and Programmable Multifunctional Nanocomposite Coatings by Yi Hou (148620)

“…The highly cross-linked continuous network endows the coating with a hardness (<i>H</i> = 0.83 GPa) higher than those of most polymers (<i>H</i> < 0.3 GPa), while the uniformly dispersed micelles decrease the Young’s modulus (<i>E</i> = 5.89 GPa) to a value as low as that of common plastics, resulting in excellent hardness and flexibility, with an <i>H</i>/<i>E</i> of 14.1% and an elastic recovery rate (<i>W</i>_e) of 86.3%. …”

Video_1_Poly I:C Activated Microglia Disrupt Perineuronal Nets and Modulate Synaptic Balance in Primary Hippocampal Neurons in vitro.MP4 by David Wegrzyn (10180829)

“…Interestingly, immunocytochemical staining of the PNN component Aggrecan revealed a clear disruption of PNNs accompanied by a significant increase of glutamatergic and a decrease of γ-aminobutyric acid-(GABA)ergic synapse numbers on PNN wearing neurons. …”

Regulation of macroscopic Cx46 currents by external Ca and Mg by Vytas K. Verselis (53583)

“…(A) Representative current–voltage (I-V) relationships (top) at different external Ca concentrations ranging from nominal (0 added) to 1.8 mM were obtained by applying slow (3 min) voltage ramps from +50 to −100 mV to a Cx46-expressing oocyte. …”

Superior Hard but Quickly Reversible Si–O–Si Network Enables Scalable Fabrication of Transparent, Self-Healing, Robust, and Programmable Multifunctional Nanocomposite Coatings by Yi Hou (148620)

“…The highly cross-linked continuous network endows the coating with a hardness (<i>H</i> = 0.83 GPa) higher than those of most polymers (<i>H</i> < 0.3 GPa), while the uniformly dispersed micelles decrease the Young’s modulus (<i>E</i> = 5.89 GPa) to a value as low as that of common plastics, resulting in excellent hardness and flexibility, with an <i>H</i>/<i>E</i> of 14.1% and an elastic recovery rate (<i>W</i>_e) of 86.3%. …”

Supporting data file. by Laura Mora-Bitria (20477525)

“…We studied Type 1 diabetes (T1D) as a paradigmatic example of autoimmunity. In T1D, variation in the Human Leucocyte Antigen (HLA) genes explains up to 50% of the genetic risk, indicating that T cells have a major role in T1D etiopathogenesis. …”