Thiostrepton inhibits growth and induces apoptosis by targeting FoxM1/SKP2/MTH1 axis in B-precursor acute lymphoblastic leukemia cells by Kuttikrishnan, Shilpa

“…Thiostrepton led downregulation of FoxM1 accompanied by decreased expression of Aurora kinase A, B, matrix metalloproteinases, and oncogene SKP2 as well as MTH1. …”
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Angiotensin receptor blocker-neprilysin inhibitor for heart failure with reduced ejection fraction by Nasrallah, Dima

“…We also discuss the evidence showing the added benefit resulting from combining ARNIs with a sodium-glucose cotransporter-2 (SGLT-2) inhibitor. …”
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Signaling pathways activated by PACAP in MCF-7 breast cancer cells by Zibara, Kazem

“…On the other hand, PACAP induced calcium release, which was decreased by pretreatment with PLC inhibitor. Finally, PACAP stimulation promoted apoptosis by increasing Bax and decreasing Bcl2 expression. …”
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Changes in expression of Kv7.5 and Kv7.2 channels in dorsal root ganglion neurons in the streptozotocin rat model of painful diabetic neuropathy by Laiche, Djouhri

“…We found 35 days post-STZ: (1) a significant decrease in Kv7.5-immunoreactivity in small (<30 μm) DRG neurons (both IB4 positive and IB4 negative) and medium-sized (30−40 μm) neurons, and (2) a significant increase in Kv7.2-immunoreactivity in small (<30 μm) neurons, and a non-significant increase in medium/large neurons. …”
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Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation by El Hasasna, Hussain

“…Furthermore, we found that while both autophagy inhibitors abolished p38 phosphorylation, only CQ led to significant decrease in pERK1/2. …”
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Experimental investigations on spray flames and emissions analysis of diesel and diesel/biodiesel blends for combustion in oxy-fuel burner by ElKelawy M.

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A novel index based on planktonic copepod reproductive traits as a tool for marine ecotoxicology studies by Mohamed Bakr, Hussain

“…At high concentrations, cadmium and silver induce an increase in EPR in the copepods Acartia tonsa and Acartia hudsonica, while exposure to mercury decreases EPR in adults by 50%. All three metals affect HS, with mercury inducing a stronger effect than cadmium and silver. …”
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Structural and magnetic properties of Ni1-xZnxFe 2O4 (x=0, 0.5 and 1) nanopowders prepared by sol-gel method by Gao P.

“…A series of nanostructured Ni-Zn ferrites Ni1-xZn xFe2O4 (x=0, 0.5 and 1) with a grain size from 24 to 65 nm have been prepared with a sol-gel method. …”
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ELECTRODE SUSPENSION FOR AQUEOUS SODIUM FLOW BATTERY by MESLAM, MENTALLAH MOHAMED HASSANIN MOHAMED HASSANIN

“…In the current study, we attempt to formulate and characterize aqueous electrode suspensions (anolytes) composed of carbon black (KB) and sodium titanate (Na2Ti3O7; NTO) dispersed in branched micelle solution. …”
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CD146, a novel target of CD44-signaling, suppresses breast tumor cell invasion. by Ouhtit, Allal

“…We have previously validated three novel CD44-downstream positively regulated transcriptional targets, including Cortactin, Survivin and TGF-β2, and further characterized the players underlying their separate signaling pathways. …”
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Effect of temperature and erosion on pitting corrosion of X100 steel in aqueous silica slurries containing bicarbonate and chloride content by Mahdi, E.

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Khalasa date palm leaf fiber as a potential reinforcement for polymeric composite materials by Mahdi E.

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Effect of hexagonal on the in-plane crushing behaviour of plain weave composite hexagonal quadruple ring system by Mahdi, E.

“…In this study, an experimental investigation into the crushing behaviour of one dimensional composite hexagonal cellular structure between two plates has been carried out. The materials have been used to accomplish the studies are the plain weave E-glass fabric and the epoxy resin. …”
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A case study to identify the hindrances to widespread adoption of electric vehicles in qatar by Khandakar, A.

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Influence of natural gas composition on adsorption in calcite Nanopores: A DFT study by Elbashier E.

“…The nanopores absorbed up to 28 and 24 molecules of CH4 and CO2, respectively, and the adsorption energy decreased to −0.0062 and −0.0075 eV/Å2 for each. …”
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Investigation of the temperature-relatedwear performance of hard nanostructured coatings deposited on a s600 high speed steel by Santecchia E.

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Effect of water absorption on the mechanical properties of long date palm leaf fiber reinforced epoxy composites by Mahdi, E.

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Cobalt phthalocyanine as a novel molecular recognition reagent for batch and flow injection potentiometric and spectrophotometric determination of anionic surfactants by El-Nemma, Eman M.

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Appropriateness of gentamicin therapeutic drug monitoring at a Middle Eastern tertiary hospital setting: a retrospective evaluation and quality audit by Al-Sulaiti, Fatima Khalifa

“…Objective: This study aimed to evaluate the appropriateness of gentamicin therapeutic drug monitoring (TDM) at a tertiary care hospital in Qatar. Methods: A one-year quantitative retrospective chart review of all gentamicin TDM records was conducted. …”
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Elaeagnus Angustifolia: a Promising Medicinal Plant for Cancer Theraby by Mohamed, Islam

“…On the other hand, western blot analysis was carried out to evaluate E-cadherin and Erk1/Erk2 expression and activation, respectively, in FaDu and SCC25 under the effect of EA extract. …”
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