Image1_Assessment of the effect of the SLC5A2 gene on eGFR: a Mendelian randomization study of drug targets for the nephroprotective effect of sodium-glucose cotransporter protein... by Gailing Liu (19503148)

“…This suggests that a 1-SD increase in HbA1c levels, regulated by the SLC5A2 gene, is associated with decreased eGFR. …”

Image6_Assessment of the effect of the SLC5A2 gene on eGFR: a Mendelian randomization study of drug targets for the nephroprotective effect of sodium-glucose cotransporter protein... by Gailing Liu (19503148)

“…This suggests that a 1-SD increase in HbA1c levels, regulated by the SLC5A2 gene, is associated with decreased eGFR. …”

Image 1_A COP1-HY5-ABI5 module regulates ABA-mediated post-germination developmental arrest.pdf by Deeksha Singh (11009626)

“…Together, our results support a model in which a double-negative feedback loop between HY5 and ABI5 contributes to ABA-mediated post-germination growth arrest.…”

Additional file 3 of A rare mutation (p.F149del) of the NT5C3A gene is associated with pyrimidine 5′-nucleotidase deficiency by Dżamila M. Bogusławska (14182524)

Decrease in oxidative phosphorylation yield in presence of butyrate in perfused liver isolated from fed rats-0 by Jean-Louis Gallis (2926)

“…The reference (methylene-diphosphonic acid) is not shown (18.40 ppm) (number of scans = 148). B: 20 min after a perfusion of butyrate 3 mmol/L, effect (from the bottom to the top) of the simultaneous addition of IAA 0.5 mmol/L (2 min) and KCN 2.5 mmol/L (10 min) (number of scans = 60).…”

Decrease in oxidative phosphorylation yield in presence of butyrate in perfused liver isolated from fed rats-1 by Jean-Louis Gallis (2926)

“…The reference (methylene-diphosphonic acid) is not shown (18.40 ppm) (number of scans = 148). B: 20 min after a perfusion of butyrate 3 mmol/L, effect (from the bottom to the top) of the simultaneous addition of IAA 0.5 mmol/L (2 min) and KCN 2.5 mmol/L (10 min) (number of scans = 60).…”

Image_5_SmDXS5, acting as a molecular valve, plays a key regulatory role in the primary and secondary metabolism of tanshinones in Salvia miltiorrhiza.jpeg by Da-chuan Zhang (14096760)

“…Here, we found that SmDXS5, a rate-limiting enzyme-coding gene located at the intersection of primary and secondary metabolism, can effectively change the transcription level and secondary metabolome profile of hairy roots of S. miltiorrhiza, and significantly increase the content of tanshinones. …”

Table_5_SmDXS5, acting as a molecular valve, plays a key regulatory role in the primary and secondary metabolism of tanshinones in Salvia miltiorrhiza.xls by Da-chuan Zhang (14096760)

“…Here, we found that SmDXS5, a rate-limiting enzyme-coding gene located at the intersection of primary and secondary metabolism, can effectively change the transcription level and secondary metabolome profile of hairy roots of S. miltiorrhiza, and significantly increase the content of tanshinones. …”

MLIF Alleviates SH-SY5Y Neuroblastoma Injury Induced by Oxygen-Glucose Deprivation by Targeting Eukaryotic Translation Elongation Factor 1A2 by Qiuzhen Zhu (2504374)

“…Furthermore, we found that eukaryotic translation elongation factor 1A2 (eEF1A2) is a downstream target of MLIF. Knockdown eEF1A2 using short interfering RNA (siRNA) almost completely abrogated the anti-apoptotic effect of MLIF in SH-SY5Y cells subjected to OGD, with an associated decrease in cell survival and an increase in expression of p-JNK and p53. …”

Microflow Liquid Chromatography Coupled to Multinozzle Electrospray Ionization for Improved Lipidomics Coverage of 3D Clear Cell Renal Cell Carcinoma by Sergey Girel (6887840)

“…With a runtime of 19 min, similar to our established analytical flow (AF/ESI) lipidomics platform, μF/mnESI produced a 16-fold median increase across 69 deuterated lipid standards. …”

<i>Atx2</i> knockdown decreases Htt and mHtt levels while Atx2 or Atx2-dPAM overexpression does not affect Htt or mHtt levels prior to aggregation formation. by Fangke Xu (7474448)

IL-17A promotes RANKL-stimulated osteoclastogenesis. by Hao Tang (44155)

SNAP-25 protein concentration in MO3.13. by Simone Agostini (760354)

Maternal Smoking during Pregnancy and DNA-Methylation in Children at Age 5.5 Years: Epigenome-Wide-Analysis in the European Childhood Obesity Project (CHOP)-Study by Peter Rzehak (212019)

“…This study thus replicates previous findings in children ages 3 to 5, 7 and 17 and confirms the postnatal stability of <i>MYO1G</i>, <i>CNTNAP2</i> and <i>FRMD4A</i> differential methylation. …”

Rab1A knockdown induced cell death not including apoptosis. by Masako Tanaka (560084)

“…<p>HT29 cells transfected with <i>Hsc70</i>, <i>Rab1A</i>, <i>Ran</i>, or <i>control</i> siRNA were subjected to serum depletion, 5-FU, or vehicle treatment for 24 h. …”

Inhibition of autophagy attenuates IL-17A-mediated osteoclastogenesis. by Hao Tang (44155)

Table_5_In vitro Neuroprotective Potential and Lipidomics Study of Olive Leaves Extracts Enriched in Triterpenoids.XLSX by Rocío Gallego (9723148)

“…Moreover, several triacylglycerols were found decreased. These results suggest triterpenoids from olive leaves as good neuroprotective candidates, and open a new gate for future experiments using in vivo models to corroborate this hypothesis.…”

Study Flow Diagram. by Elizabeth S. Munroe (21568166)

Overall movement and disability scales in the patients with <i>DYT</i>-1 dystonia, PKAN, and tardive dystonia. by Hye Ran Park (844306)

Percentage of violacein production in <i>Chromobacterium violaceum</i> by the most active synthesized 1,2,3,5-tetrazine derivatives (4a, 4b and 4c). by Jean Paul Dzoyem (6424445)