Proteasome-Mediated Proteolysis of SRSF5 Splicing Factor Intriguingly Co-occurs with SRSF5 mRNA Upregulation during Late Erythroid Differentiation by Osman Breig (388133)

“…In this study, we show that SRSF5 protein decreases drastically during erythroid cell differentiation, contrasting with a concomitant upregulation of SRSF5 mRNA level. …”

Table_5_Disease Activity-Associated Alteration of mRNA m5 C Methylation in CD4+ T Cells of Systemic Lupus Erythematosus.xlsx by Gangqiang Guo (3278922)

“…Eleven methylation modifications (including elevated Am, 3′OMeA, m¹A, and m⁶A and decreased Ψ, m³C, m¹G, m⁵U, and t⁶A levels) were detected in CD4⁺ T cells of patients with SLE. …”

Temsirolimus increases progerin clearance via autophagy. by Diana Gabriel (3608093)

Video5_Magnetospheric responses to solar wind Pc5 density fluctuations: Results from 2D hybrid Vlasov simulation.MP4 by Hongyang Zhou (2352637)

“…With the new time-varying boundary setup, we introduce a monochromatic Pc5 range periodic density variation in the solar wind. …”

RSL-3 cancels the effect of NeuroD1 on promoting cell viability. by Ping Huang (30439)

DAS and Y27632 down-regulated the mRNA and protein expression of CK8-RhoA/ROCK1 pathway and up-regulated TJs expression in intestines of infected mice. by Wen Wen Zheng (17721404)

Identification of a Novel Hybridization from Isosorbide 5‑Mononitrate and Bardoxolone Methyl with Dual Activities of Pulmonary Vasodilation and Vascular Remodeling Inhibition on Pu... by Yusheng Cheng (4817790)

“…Given the clinical therapeutic efficacy of oral-dosed bardoxolone methyl (<b>1</b>) and the selective vasodilatory effect caused by inhalation of nitric oxide (NO) on pulmonary arterial hypertension (PAH) patients, a new hybrid (CDDO-NO, <b>2</b>) from <b>1</b> and NO donor isosorbide 5-mononitrate (<b>3</b>) was designed and synthesized. …”

Deletion of <i>Smyd1</i> by <i>Tg-Nkx2</i>.<i>5-cre</i> leads to a delayed embryonic lethal cardiac phenotype. by Tara L. Rasmussen (118770)

“…<b>E.</b> Decreased proliferation was observed in the hearts of E10.5 <i>Smyd1</i> Tg-CKO embryos. …”

Loss of FAM83A expression induces apoptosis and inhibits PI3K/Akt signaling. by Courtney A. Bartel (3993173)

“…(C) Live cells were stained with an antibody detecting the early apoptosis marker Annexin V. Knockdown of FAM83A resulted in elevated expression of Annexin V. …”

SRSF5 expression in primary ex-vivo erythroid precursors. by Osman Breig (388133)

“…After 2 days of maturation, these cells display a cell size decrease (low FSC), and cell surface phenotype changes, including Kit decrease and higher levels of CD71 and Ter119.B. …”

HMBOX1 reverses autophagy mediated 5-fluorouracil resistance through promoting HACE1-induced ubiquitination and degradation of ATG5 in colorectal cancer by Yan Gao (93649)

“…This results in decreased ATG5 levels, inhibiting autophagy and thus reducing 5-FU resistance in colorectal cancer cells both <i>in vitro</i> and <i>in vivo</i>. …”

Role of the −5 bp in <i>sodB</i> regulation. by Beth M. Carpenter (373215)

“…<p>WT G27, WT 26695, and the “−5 bp swap” strain were grown as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0005369#s2" target="_blank">Materials and Methods</a>, and RNA was isolated under iron replete and iron-depletion shock conditions. …”

<i>In vitro</i> characterization of key marker proteins AQP5, ANO1, α-SMA, and CEACAM5 in cultures of the SG by immunofluorescence staining. by Patricia Klaka (4347595)

“…<p>(A) Stained secretory coil (sc) and duct (du) sections of native human sweat glands were analyzed in axillary skin tissue (a,d,g,j) compared to <i>in situ</i> glands (dashed lines) with outgrowing cells in 2D cultures (b,e,h,k) and 3D models (c,f,i,l). …”

Effect of treatment with CNCs on inflammation and fibrosis in hamsters infected with <i>O</i>. <i>viverrini</i> and fed an HFF diet. by Chutima Sitthirach (12700144)

JetPEI transfection reagent works for transfecting efficiently STAT6 siRNAs <i>in vitro</i>. by Carmen Salguero-Aranda (6690044)

Table_5_Alteration of mRNA 5-Methylcytosine Modification in Neurons After OGD/R and Potential Roles in Cell Stress Response and Apoptosis.XLSX by Huan Jian (10077037)

“…<p>Epigenetic modifications play an important role in central nervous system disorders. As a widespread posttranscriptional RNA modification, the role of the m⁵C modification in cerebral ischemia-reperfusion injury (IRI) remains poorly defined. …”

NeuroD1 increases HCC cell death resistance. by Ping Huang (30439)

Overexpression of DJ-1 full length prior to oxidative stress leads to decreased levels of H₂O₂-induced ROS generation by RPE cells. by Karen G. Shadrach (429721)

ASO-miR-129-5p down-regulates miR-129-5p and reduces proliferation and migration of Hep-2 cells by MingHua Li (3522803)

“…<p>. (A) miR-129-5p expression was significantly decreased after ASO-miR-129-5p transfection compared to GFP transfection (control) or untreated Hep-2 cells (Hep-2 cell) measured by real-time RT-PCR. (* <i>P</i><0.05). …”

Image_5_5-Methylcytosine Related LncRNAs Reveal Immune Characteristics, Predict Prognosis and Oncology Treatment Outcome in Lower-Grade Gliomas.tif by Jiheng Zhang (11953919)

“…Consequently, we identified four lncRNAs, including LINC00265, CIRBP-AS1, GDNF-AS1, and ZBTB20-AS4, and established a novel m5C-related lncRNAs signature (m5CrLS) that was effective in predicting prognosis. …”