Search alternatives:
sizes decrease » size increase (Expand Search), scores decreased (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 nn » 5 non (Expand Search), 59 nn (Expand Search), 5 nm (Expand Search)
sizes decrease » size increase (Expand Search), scores decreased (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 nn » 5 non (Expand Search), 59 nn (Expand Search), 5 nm (Expand Search)
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Attenuation of spheroid size decrease or MUC5AC increase by hit compounds.
Published 2023“…<p>Final hit compounds (with hit concentration and corresponding target) that <b>A)</b> increased bronchosphere size compared to DMSO + 3% CSE control bronchospheres or <b>B)</b> decreased secreted MUC5AC. …”
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Primary small molecule screen to identify attenuators of CSE-induced decrease in size and increase in MUC5AC.
Published 2023“…Hit compounds at 1 and 10μM concentrations that <b>B)</b> increased spheroid size (swell) or <b>C)</b> decreased MUC5AC staining in the lumen relative to DMSO and CSE 3%-treated bronchospheres. …”
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Supplementary Material for: Decreases in Brain Size and Encephalization in Anatomically Modern Humans
Published 2021“…Over the past 50,000 years, however, both body size and brain mass have decreased but little is known about the scaling relationship between the two. …”
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Validation of primary screen hits reveals compounds that recapitulate increased spheroid size (swell) or decreased MUC5AC in the lumen.
Published 2023“…Compounds that appeared to cause toxicity were identified by observing a significant decrease in spheroid counts in the swell readout or a significant decrease in the total nuclear intensity of the MUC5AC ratio readout. …”
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Supplementary Material for: Longitudinal Decrease in Left Ventricular Size with Age: Impact on Mortality and Cardiovascular Hospitalization
Published 2025“…Conclusions: A progressive decrease in LVEDD in normal-sized hearts was independently associated with adverse outcomes, highlighting the prognostic importance of declining LV size.…”