The Intensity of IUGR-Induced Transcriptome Deregulations Is Inversely Correlated with the Onset of Organ Function in a Rat Model by Daniel Vaiman (83223)

“…We show that (1) expressional alterations are apparently stronger in organs functioning late in foetal or postnatal life than in organs that are functioning early (2) hierarchical classification of the deregulations put together kidney and placenta in one cluster, liver, lungs and heart in another; (3) the epigenetic machinery is set up especially in the placenta, while its alterations are rather mild in other organs; (4) the genes appear deregulated in chromosome clusters; (5) the altered expression cascades varies from organ to organ, with noticeably a very significant modification of the complement and coagulation cascades in the kidney; (6) we found a significant increase in TF binding site for HNF4 proteins specifically for liver genes that are down-regulated in IUGR, suggesting that this decrease is achieved through the action of HNF transcription factors, that are themselves transcriptionnally induced in the liver by IUGR (x 1.84 fold). …”

Image_1_Causality between sarcopenia and diabetic nephropathy: a bidirectional Mendelian randomization study.tif by Linan Ren (5561837)

“…</p>Results<p>According to a forward MR analysis, a genetically predicted decrease in appendicular lean mass is associated with an increased risk of developing DN risk (inverse variance weighting[IVW]: odd ratio [OR] = 0.863, 95% confidence interval [CI] 0.767-0.971; P = 0.014). …”

Orchio-Septopexy: A new technique to cover and fix detorsed testis undergoing fasciotomy of tunica albuginea by Mohammed Elifranji (13160309)

“…Fashioning the TVF can be tedious in cases of severe scrotal edema. Herein we present a technique that facilitates and expedites the procedure, maintaining the fasciotomy area decompressed. …”

Interaction of meropenem with ‘N’ and ‘B’ isoforms of human serum albumin: a spectroscopic and molecular docking study by Md. Tabish Rehman (355007)

“…Strong binding of carbapenems to HSA may lead to decreased bioavailability of the drug. The non-optimal drug dosage will provide a positive selection pressure on bacteria to develop resistance. …”

Continuous Flow Synthesis of Ethyl Diazoacetate and CFD Analysis of Micromixing Efficiency in a Microreactor by Nan Wang (21935)

“…Flow chemistry coupled with microreactor technology represents a contemporary advancement in the chemical industry. …”

Role of psychosocial status in predicting health-related quality of life at 1-year follow-up among newly diagnosed people living with HIV by Yunxiang Huang (7535135)

“…</p><p>Method</p><p>A consecutive sample of newly diagnosed PLWH was recruited from Changsha Center for Disease Control and Prevention in Hunan Province, China. …”

Targeting of Vps34 reduces B16F10 tumor growth and working model for Vps34-dependent regulation of eTreg transitional heterogeneity and maintenance. by Erienne G. Norton (9612079)

Created with BioRender.com. by Simone Schiavo (15999287)

“…Thirteen patients had HFpEF (mean LVEF 55 ± 7%), and seven patients had HFrEF (mean LVEF 35 ± 8%) as well as concomitantly decreased right ventricle function (n = 5), moderate/severe tricuspid regurgitation (n = 3), or pulmonary hypertension (n = 5). …”

Hyperbaric oxygen therapy details. by Simone Schiavo (15999287)

“…Thirteen patients had HFpEF (mean LVEF 55 ± 7%), and seven patients had HFrEF (mean LVEF 35 ± 8%) as well as concomitantly decreased right ventricle function (n = 5), moderate/severe tricuspid regurgitation (n = 3), or pulmonary hypertension (n = 5). …”

Histological changes of the vasoactive markers in the thoracic aorta. by Bálint Bányai (16384614)

The inhibitory effect of 1,8-cineole on the erythrocytic cycle of <i>Plasmodium falciparum</i> is not reversible. by Edgleyson C. dos Santos (12536575)

Unisex schistosome infection and PD-1 expression in liver T cells. by Liaoxun Lu (179293)

The effect of phenotype switching on ILEI expression. by Ken Noguchi (255943)

Calpains participate in the expression, activity and secretion of MMP2 and MMP9. by Muhammad Yasir Asghar (423105)

Pharmacology of the Adenosine A₃ Receptor in the Vasculature and Essential Hypertension - Fig 4 by Ming-Fen Ho (2265538)

“…<p>Mean decrease in (A) left ventricular developed pressure (LVDP) and (B) the left ventricle contractility (dP/dt) maximum at the concentration of 10^-5M of APNEA or CL-IB-MECA for control normotensive rats (NT) and spontaneously hypertensive rats (SHR). …”

S1 Data - by Aleksi J. Nummela (18764801)

“…</p><p>Results</p><p>At 24 h, increased lactate, adjusted hazard-ratio 2.25, 95% CI [1.53; 3.30], p<0.001, and decreased branched-chain amino acids (BCAA) leucine 0.64 [0.5; 0.82], p = 0.007, and valine 0.37 [0.22; 0.63], p = 0.003, associated with 6-month mortality. …”

Key inputs in the model. by Jie Pan (187977)

“…Consequently, a scenario analysis based on subgroups of Chinese females was conducted for this study. …”

Demographics. by Aleksi J. Nummela (18764801)

“…</p><p>Results</p><p>At 24 h, increased lactate, adjusted hazard-ratio 2.25, 95% CI [1.53; 3.30], p<0.001, and decreased branched-chain amino acids (BCAA) leucine 0.64 [0.5; 0.82], p = 0.007, and valine 0.37 [0.22; 0.63], p = 0.003, associated with 6-month mortality. …”

Fructooligosaccharides (FOS) or dead <i>L</i>. <i>salivarius</i> feeding reduced enteric bacteria as well as <i>K</i>. <i>pneumoniae</i> translocation to liver and increased hepati... by Shu-Han Lin (4020353)

“…<i>salivarius</i> supplementation significantly decreased serum ALT levels in STZ-DM mice. (B) STZ-DM mice demonstrated a significant increase of <i>K</i>. …”

UNC-85 mutations restore the sterility of <i>H2B 3KO C</i>. <i>elegans</i>. by Ruixue Zhao (2744689)

“…<b>(B)</b> Localization of the endogenously GFP::tagged HIS-58 on chromosomes during metaphase in wild-type (WT) one-cell embryos. Scale bar, 5 μm. <b>(C)</b> Loss of H2B decreased brood size. …”