DataSheet1_Unraveling the therapeutic mechanisms of dichloroacetic acid in lung cancer through integrated multi-omics approaches: metabolomics and transcriptomics.CSV by Malong Feng (16076690)

“…<p>Objective: The aim of this study was to investigate the molecular mechanisms underlying the therapeutic effects of dichloroacetic acid (DCA) in lung cancer by integrating multi-omics approaches, as the current understanding of DCA’s role in cancer treatment remains insufficiently elucidated.</p><p>Methods: We conducted a comprehensive analysis of publicly available RNA-seq and metabolomic datasets and established a subcutaneous xenograft model of lung cancer in BALB/c nude mice (n = 5 per group) treated with DCA (50 mg/kg, administered via intraperitoneal injection). …”

Repression of YEATS2 induces cellular senescence in hepatocellular carcinoma and inhibits tumor growth by Qi Wu (263110)

“…Ultimately, our <i>in vivo</i> research utilizing a nude mouse tumor model revealed a notable decrease in both tumor volume and weight after the suppression of YEATS2 expression. …”

Performance and economic viability of tambaqui, Colossoma macropomum, selectively bred for weight gain by Ana Carla Carvalho SILVA (10374162)

“…The total production cost estimations indicated that fish from family B would allow for a 4% reduction in the average fixed cost and a 1% decrease in the total average production cost.…”

Chronic intermittent exposure to ayahuasca during aging does not affect memory in mice by N.F. Correa-Netto (6510125)

“…During aging, there was significant impairment in the evocation (but not acquisition) of spatial reference memory and in habituation to the open field. There was also a decrease in locomotor activity in the open field and EPM tests, whereas the anxiety parameters were unaltered. …”

Table_2_Characteristics of steroid hormones in systemic lupus erythematosus revealed by GC/MS-based metabolic profiling.docx by Dehong Wu (2236318)

“…Furthermore, we identified the elevation of two sterols (Lan and Chol), and the reduction of one corticoid (11-DeoxyF) and two progestins (5α-DHP and 11β-OH-Prog) in patients.…”

Parametric dependence of polarization reversal effects on the particle pitch angle scattering by EMIC waves by Yuequn Lou (10003955)

“…While the increase of electron diffusion coefficients can be up to a factor of 5, the decrease of proton diffusion coefficients can be larger than an order of magnitude. …”

Table_1_Characteristics of steroid hormones in systemic lupus erythematosus revealed by GC/MS-based metabolic profiling.docx by Dehong Wu (2236318)

“…Furthermore, we identified the elevation of two sterols (Lan and Chol), and the reduction of one corticoid (11-DeoxyF) and two progestins (5α-DHP and 11β-OH-Prog) in patients.…”

Image_1_Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer.TIFF by Leandro M. Martinez (7323791)

“…Regulatory T (Treg) cells accumulate in advanced breast cancers, and predict poor outcome. We have shown before that ablation of Treg cells in established tumors leads to significant decrease in primary and metastatic tumor burden. …”

Data_Sheet_1_Deep Convolutional Neural Network Based Interictal-Preictal Electroencephalography Prediction: Application to Focal Cortical Dysplasia Type-II.docx by Yoon Gi Chung (9604061)

“…Classification performances were evaluated based on accuracy, F1 score, precision, and recall with respect to the above-mentioned three parameters. We found that (1) a 5 min preictal length provided the best classification performance, showing a remarkable enhancement of >13% on average compared to that with the 120 min preictal length; (2) four electrodes provided considerably high classification performance with a decrease of only approximately 1% on average compared to that with all channels; and (3) there was minimal performance change when quadrupling the sampling frequency from 128 Hz. …”

Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib drug response in chronic lymphocytic leukemia by André Rendeiro (101018)

“…In CLL cells, this program starts with a sharp decrease of NF-κB binding, followed by reduced regulatory activity of lineage-defining transcription factors (including PAX5 and IRF4) and erosion of CLL cell identity, finally leading to the acquisition of a quiescence-like gene signature which was shared across several immune cell types. …”

Cold ischemia time alters cell-type specific senescence leading to loss of cellular integrity in mouse lungs by Gagandeep Kaur (1458919)

“…Annexin V-PI staining further revealed a prominent increase in the number of necrotic cells at 4-h CIT, thus suggesting that most of the cells undergo cell death within a few hours of cold ischemic injury. …”

Image_2_Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer.TIFF by Leandro M. Martinez (7323791)

“…Regulatory T (Treg) cells accumulate in advanced breast cancers, and predict poor outcome. We have shown before that ablation of Treg cells in established tumors leads to significant decrease in primary and metastatic tumor burden. …”

Code: Species diversity and habitat fragmentation per se: The influence of local extinctions and species clustering by Hans-Joachim Poethke (17407745)

Supplementary Material for: Acute myelin oligodendrocyte glycoprotein (MOG)-IgG optic neuritis without optic nerve enhancement by Jeyanathan B. (20374227)

“…While acute MOG-ON usually presents with optic nerve enhancement, recognizing atypical presentations is critical in accurate diagnosis and effective management. Case Presentation: We herein present a case of a 67-year-old woman presenting with sudden decrease in vision in the right eye. …”

Rational Design, Chemical Syntheses, and Biological Evaluations of Peripherally Selective Mu Opioid Receptor Ligands as Potential Opioid Induced Constipation Treatment by Boshi Huang (3080169)

“…Herein, we introduced a highly polar aromatic moiety, for example, a pyrazolyl or imidazolyl ring to decrease CNS MPO scores in order to reduce passive BBB permeability. …”

Table1_Retrospective analysis of pediatric sepsis and the burden of antimicrobial resistance in Duhok, Kurdistan Region of Iraq.docx by Delveen R. Ibrahim (18023530)

“…A decrease in sepsis rate was observed during the COVID-19 pandemic. …”

Analysis of Narrow band Vegetation indices of Leaves using Cross validation Procedures by Dr.E.N. Ganesh (12315038)

“…Cross-validation techniques have been used to</p> <p>evaluate the predictive energy of the regression model. We discovered a substantial dating among the slim band SAVI2</p> <p>and the leaf region index (R2 =0.78, RMSE=0.57). …”

Actual Vs predicted revenue. by Guibing You (21728593)

“…To address this challenge, we propose F-TransR, a Transformer-based multimodal revenue prediction model. …”

Video_2_Exoskeleton Walk Training in Paralyzed Individuals Benefits From Transcutaneous Lumbar Cord Tonic Electrical Stimulation.WMV by Elena Y. Shapkova (8889032)

“…In addition, in the control group (n = 16, AIS A-7, B-5, C-4), we performed EWT without SCES. …”

Video_2_Profiling of Blood-Brain Barrier Disruption in Mouse Intracerebral Hemorrhage Models: Collagenase Injection vs. Autologous Arterial Whole Blood Infusion.MP4 by Peijun Jia (11334594)

“…The results showed that the BBB leakage was associated with a decrease in TJ protein expression and an increase in MMP-9 activity and AQP4 expression on day 3 in the c-ICH model compared with that on day 5 in the b-ICH model. …”