<i>PHO5</i> AS elongation negatively affects kinetics of histone removal at the <i>PHO5</i> gene promoter upon induction. by Ana Novačić (8373573)

Subjects:

Induction of <i>PHO5</i> AS elongation by depletion of Nrd1 from the nucleus delays expression of the <i>PHO5</i> gene. by Ana Novačić (8373573)

Subjects:

HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching. by Michael Anthony Ruiz (726055)

“…However, transfection of SUZ12 siRNA significantly reduced endothelial branching compared to HG+control siRNA. [NG+control siRNA = 5mM D-glucose + 100nM control siRNA, HG+control siRNA = 25mM D-glucose + 100nM control siRNA, HG+EZH2 siRNA = 25mM D-glucose + 100nM EZH2 siRNA, HG+SUZ12 siRNA = 25mM + 100nM SUZ12 siRNA; identical letters represent groups that are not significantly different; p < 0.05; n = 6; data expressed as mean ± SEM, normalized to U6 or β-actin and expressed as a fold change of NG+control siRNA].…”

Delphinidin alters VEGF-A splicing to increase VEGF-A₁₆₅b and decrease total VEGF-A expression. by Megan Stevens (3964886)

“…<p><b>A)</b> Treatment of podocytes with delphinidin chloride (10 μg/ml) under normal glucose (NG; 5 mM glucose + 25 mM mannitol) and high glucose (HG; 30 mM glucose, 1 ng/ml TNFα, 1 ng/ml IL-6, and 100 nM insulin) for 48 hrs increased the protein expression of VEGF-A₁₆₅b relative to total VEGF-A₁₆₅ (quantified in <b>B</b>; *p<0.05 vs NG, †p<0.05 vs HG; n = 3 biological repeats; One-way ANOVA with Bonferroni post-hoc test for comparison between pairs; <b>A</b>—the same blot was first probed with VEGF-A₁₆₅b before stripping and reprobing with panVEGF-A). …”

ND-75^KD flies have reduced mobility, seizures and decreased lifespan. by Lucy Granat (5570813)

Regression of soil respiration (Rs) and soil temperature (T) fitted models of (a) control, (b) low burn severity, and (c) high burn severity in the growing season. by Tongxin Hu (4217563)

Subjects:

Relationships between empty body lipid weight decrease and corrected amounts of pollutants excreted through faeces (faecal output–feed input) for TCDD (○, ●), and PCBs 153 (□, ■) and 126 (Δ, ▲) over a 57-day depuration period in ewes receiving a control well-fed and non-supplemented treatments (CTL: ○, □, Δ; <i>n</i> = 4), or an underfed and mineral oil supplemented treatment (UFMO: ●, ■, ▲; <i>n</i> = 5). by Sylvain Lerch (1494349)

“…<p>Relationships between empty body lipid weight decrease and corrected amounts of pollutants excreted through faeces (faecal output–feed input) for TCDD (○, ●), and PCBs 153 (□, ■) and 126 (Δ, ▲) over a 57-day depuration period in ewes receiving a control well-fed and non-supplemented treatments (CTL: ○, □, Δ; <i>n</i> = 4), or an underfed and mineral oil supplemented treatment (UFMO: ●, ■, ▲; <i>n</i> = 5).…”

Schematic of the D2 model (standard non-competitive model). by Hidetoshi Urakubo (578508)

MBOAT7 rs641738 (C>T) is associated with NAFLD progression and decreased ASCVD risk in elder Chinese population by Zhang jing (14062485)

Prolonged transforming growth factor (TGF)-βtreatment induced a decrease in total Smad2 and/or Smad3 in many cell strains by Kimberly A Brown (26546)

Fig 5 - by Chen Ruiying (8807294)

Regression of soil respiration (Rs) and soil temperature (T) fitted models of (a) control, (b) low burn severity, and (c) high burn severity in the non-growing season. by Tongxin Hu (4217563)

Subjects:

MeV disrupted mitochondrial network and cellular metabolism. by Pierre Khalfi (7868252)

Clinical significance of CD44V expression in primary colon cancer tissues. by Takeshi Kaida (6532907)

Fig 5 - by Melissa A. Johnson (3847954)

FGF18 injections increase TIMP1 and decrease MMP13 and NOGGIN, suggesting healing of degeneration induction of anabolic effect. by Flavia Gomes Velasque Gama (21175112)

Functional characterization of the V9D and R10C substitutions in chicken ARF. by Doreen Schwochow Thalmann (3912649)

“…Spectra of all peptides in free form and at 25 μM concentration in complex with MDM2_204-298 are shown in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006665#pgen.1006665.s008" target="_blank">S5 Fig</a>. …”

<i>In vitro</i> treatment with the broad spectrum caspase inhibitor Q-VD-OPh reduces the number of active caspase-3-positive cells in parallel with a decrease in the entry of micro... by María Martín-Estebané (623506)

Antagonizing BMP type I receptors decreases cell growth, proliferation, and clonogenicity of lung cancer cell lines. by Elaine Langenfeld (402034)

“…<p>(<b>A</b>) A549 and H1299 cells cultured in DMEM 5% FCS were treated with DMSO, 10 µM Dorsomorphin, 1 µM DMH1, 1 µM DMH2, or 1 µM LDN for 7 days and cell counts performed. …”

Nimodipine does not affect Aβ levels in cortex or hippocampus. by Katherine R. Sadleir (12035242)