LncRNA LINC00707 serves as a sponge of miR-382-5p to alleviate lipopolysaccharide (LPS)-induced WI-38 cell injury through upregulating NKAP in infantile pneumonia by Lu Chen (75170)

“…The binding between miR-382-5p and LINC00707 or NKAP was predicted by starBase v2.0 and then verified by a dual-luciferase reporter and RNA Immunoprecipitation (RIP) assays. …”

Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study by Patrick Linsel-Nitschke (87537)

“…</p><h3>Findings</h3><p>Each copy of the minor T allele of SNP rs2228671 within <em>LDLR</em> (frequency 11%) was related to a decrease of LDL-C levels by 0.19 mmol/L (95% confidence interval (CI) [0.13–0.24] mmol/L, p = 1.5×10⁻¹⁰). …”

ChIP analysis of SATB1 binding on the NOXA promoter region and the mbr element <i>in vivo</i>. by Yin Yang (35103)

Table_5_Association of Different Restriction Levels With COVID-19-Related Distress and Mental Health in Somatic Inpatients: A Secondary Analysis of Swiss General Hospital Data.docx by Nicola Julia Aebi (10571438)

Table 1_LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis.docx by Yihan Liu (2258221)

“…</p>Results<p>OIP5-AS1 expression was significantly decreased in LUAD tissues and associated with poor survival. …”

Data Sheet 1_LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis.docx by Yihan Liu (2258221)

“…</p>Results<p>OIP5-AS1 expression was significantly decreased in LUAD tissues and associated with poor survival. …”

Expression of hLPL in striated muscle following <i>in vivo</i> infection with RCAS-hLPL. by Katherine E. Gadek (3276996)

Hepatitis C Virus (HCV) Evades NKG2D-Dependent NK Cell Responses through NS5A-Mediated Imbalance of Inflammatory Cytokines by Damien Sène (237641)

“…Using an endotoxin-free recombinant NS5A protein, we show that NS5A stimulation of monocytes through Toll-like Receptor 4 (TLR4) promotes p38- and PI3 kinase-dependent IL-10 production, while inhibiting IL-12 production. …”

BA attenuated the decrease in the integrity and increase in the permeability of the epithelial barrier injury induced by LPS in Caco2 cell monolayers. by Luqiong Liu (11537092)

Generation of luciferase reporter viruses bearing deletions of the core LAT promoter. by Michael P. Nicoll (3175491)

Target specificity, <i>in vivo</i> pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma by Peter Y. Yu (4281448)

“…The purpose of this work was to develop and test a novel putative STAT3 inhibitor, LY5.</p><p>Methods and findings</p><p>An <i>in silico</i> fragment-based drug design strategy was used to create LY5, a small molecule inhibitor that blocks the STAT3 SH2 domain phosphotyrosine binding site, inhibiting homodimerization. …”

DataSheet_1_The Relationship Between Pediatric Gut Microbiota and SARS-CoV-2 Infection.docx by Lorenza Romani (8487723)

“…All GM paired-comparisons disclosed comparable results through all time points. The comparison between COVID-19 and Non–COVID-19 cohorts highlighted a reduction of Abiotrophia in the COVID-19 cohort (p < 0.05). …”

DataSheet_2_The Relationship Between Pediatric Gut Microbiota and SARS-CoV-2 Infection.xlsx by Lorenza Romani (8487723)

“…All GM paired-comparisons disclosed comparable results through all time points. The comparison between COVID-19 and Non–COVID-19 cohorts highlighted a reduction of Abiotrophia in the COVID-19 cohort (p < 0.05). …”

LY5 inhibits STAT3 phosphorylation in lung metastases but does not inhibit lung metastasis formation. by Peter Y. Yu (4281448)

LY5 does not inhibit growth of <i>ex vivo</i> pulmonary metastasis. by Peter Y. Yu (4281448)

Decreased number of myofibroblasts on stiff-to-soft gels was not due to apoptosis. by Huan Wang (109286)

Acute JMV2959 treatment decreases alcohol intake in rats. by Petra Suchankova (400313)

“…<p>(A) The acute effects of the GHS-R1A antagonist JMV2959 (1 or 3 mg/kg) administration on alcohol intake was evaluated at 1 hour time interval after both two and five months of voluntary alcohol consumption. …”

Table_1_Tipping point of plant functional traits of Leymus chinensis to nitrogen addition in a temperate grassland.DOCX by Guojiao Yang (12158151)

“…We chose the native, perennial clonal grass, Leymus chinensis in Inner Mongolia steppe, and conducted a field experiment, in which six N addition rates (0, 2, 5, 10, 20, and 50 g N m^–2 year^–1) and five N compound types [NH₄NO₃, (NH₄)₂SO₄, NH₄HCO₃, CO(NH₂)₂, slow-release CO(NH₂)₂] are considered. …”

Acute JMV2959 treatment decreases alcohol preference in rats. by Petra Suchankova (400313)

“…<p>(A) Acute administration of the GHS-R1A antagonist JMV2959 (1 or 3 mg/kg) decreases the alcohol preference compared to vehicle at 1 hour time interval in rats voluntarily consuming alcohol for two and five months before the treatment. …”

Inhibition of the lysosomal protease decreased the apoptosis induced by EV71. by Xueyan Xi (5654083)