Modeling experimental findings on lamotrigine application. by Michele Migliore (323322)

“…<p>(<i>left</i>) experimental recordings demonstrating a decrease in dendritic (but not somatic) firing after <i>I_h</i> up-regulation caused by application of the anticonvulsive drug Lamotrigine (adapted from Fig. 2d of <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0036867#pone.0036867-Poolos1" target="_blank">[4]</a>); (<i>right</i>) simulation of somatic (<i>bottom</i>) and dendritic (<i>top</i>, ∼200 µm from soma) recordings during a 500 ms current injection of 0.55 or 0.82 nA, respectively, before (control) and during LTG application (bar above plots); <i>g_{h_pk}</i> = 0.01 mS/cm², <i>lk</i> = 0.5 (control), <i>lk</i> = 0.8 (LTG).…”

Echocardiography analysis was followed up to 6 weeks of reperfusion to examine the chronic effects of IR injury. by Megumi Eguchi (333410)

“…On the contrary, STZ mice developed concentric hypertrophy as shown by decreased LVEDV, LVESV and increased EF (A,B,C). M-mode image showing the increase in the LV wall and decrease in interstitial space in STZ heart (D). …”

Receptive fields of two neurons in the optic tectum. by Josine Verhaal (400568)

“…The neuron responded with a short delay to black (40 ms) and with a longer delay to white (130 ms) and therefore could be responsive to decrease in luminance. …”

Sequential Injection Analysis of Butyrylcholinesterase Using Butyrylcholine Ion-Selective Electrode Detector (Supporting Information) by Narimasa KOIZUMI (13719592)

“…In the present SIA method using the BuCh-ISE detector based on <i>α</i>-cyclodextrin membrane, BChE in the concentration range of 0.015–0.50 units/mL was determined at a BuCh concentration of 2.0 mmol dm⁻³ and a reaction time of 5.0 min. …”

Naloxone does not block loperamide effects on mechanosensitivity of C-fibers. by Matthias Ringkamp (253465)

“…<p>A) Naloxone pretreatment does not prevent the loperamide (5 µg/10 µl) – induced increase in mechanical thresholds of C-fibers. …”

Figure 4. Transcriptional effects of SOX15 perturbation. by Merrick Pierson Smela (7036586)

Over-expression of Fas2 in the wing imaginal disc causes an EGFR-dependent reduction in organ size. by Luis Garcia-Alonso (152388)

“…At right, a clone in the Posterior compartment between vein V and the posterior wing margin (green arrow) causes an abnormal shape due to the reduction in size of the posterior region of the wing, while another clone between veins II and III causes a size decrease in the anterior compartment (green arrow). …”

Noise reduction and quantification of fiber orientations in greyscale images by Maximilian Witte (8313381)

“…A comparison to a state-of-the-art band-pass method revealed that the AF method is more suitable for the application on greyscale fiber images, since the error of the fiber dispersion significantly decreased from (33.9 ± 26.5)% to (13.2 ± 12.7)%. …”

Table_1_Impact of changing treatment strategy based on circulating tumor cells on postoperative survival of breast cancer.xls by Zihan Wang (3129810)

“…Among the 28 patients who were CTC positive and ER and PR-negative, 11 used capecitabine. Compared with non-users, the capecitabine users had higher CTC clearance rates (100.0% vs. 52.9%, p=0.01) and more significant decrease in CTC-positive values (2.09 ± 1.14 vs. 0.82 ± 1.67, p=0.04). …”

Conditioning in the promotion and uniformization of Umbu seed germination by Renato Teo Barros (4959271)

“…<div><p>Abstract Seed dormancy may decrease during storage and some environmental conditions may accelerate this process. …”

Decision boundary dynamics modulated by theta activity. by Nadja R. Ging-Jehli (10925910)

“…<p><b>(A)</b> Exemplified scheme for integrating mean activation in theta-frequency band during pre-response (z-scored mean activation during the last 500 ms before response) and poststimulus (z-scored mean activation during the first 500 ms after stimulus onset) periods as trial-based neural regressors into the best-fitting model. …”

Effects of resistance exercise versus combined training on post-exercise hypotension in women with metabolic syndrome by Ramires Alsamir Tibana (8977688)

“…Therefore, RE and COMB elicited post-exercise hypotension in women with MS; COMB provided a greater decrease which may be of value in the prevention and treatment of cardiovascular disorders.…”

Fungal and bacterial successions in the process of co-composting of organic wastes as revealed by 454 pyrosequencing by Polina Galitskaya (4529134)

“…Analysis by non-metric multidimensional scaling (NMDS) revealed that the bacterial communities of the two composts became progressively more similar; a similar trend was followed by the fungal community.…”

<b>Pancreatic</b><b> </b><b>β cell TRAPδ deficiency reduces insulin </b><b>production but improves insulin sensitivity</b> by Jiyun Guo (19439922)

Luciferase reporter assay. by Akihito Tsubota (562807)

“…<p>miR-17-5p inhibited the luciferase activity of the wild-type MAP3K8 3′UTR construct (right), whereas no decrease in activity was observed in cells co-transfected with the mutant MAP3K8 3′UTR construct (left) or mock plus wild-type or mutant construct (right and left, respectively). …”

Data_Sheet_1_Cardiac Magnetic Resonance Imaging Right Ventricular Longitudinal Strain Predicts Mortality in Patients Undergoing TAVI.PDF by Johannes Schmid (2092099)

“…</p><p>Results: Of 133 patients undergoing CMR, 113 patients were included in the analysis. Mean age was 81.8 ± 5.8 years, and 65% were female. …”

Predicting Allosteric Effects from Orthosteric Binding in Hsp90-Ligand Interactions: Implications for Fragment-Based Drug Design - Fig 3 by Arun Chandramohan (2813848)

“…<p><b>(A)</b> The absolute difference in numbers of deuterons (inferred from difference in mass in Daltons (Da) (y-axis) between the free and ligand bound state is plotted for each pepsin digest fragment listed from the N to C terminus (x-axis) of Hsp90 for each Deuterium exchange time point (t = 0.5, 2, 5, 10 min) in a ‘difference plot’. …”

Table_1_Soluble HLA-G Expression Inversely Correlates With Fetal Microchimerism Levels in Peripheral Blood From Women With Scleroderma.docx by Julie Di Cristofaro (473988)

“…Finally, women with SSc had lower sHLA-G independently of the eight HLA-G 5′URR/3′UTR polymorphisms, although they were statistically more often homozygous than heterozygous for HLA-G polymorphism genotypes −716 (G/T), −201 (G/A), 14 bp (ins/del), and +3,142 (G/A) than healthy women. …”

Individual-based simulations of colonization for two neutral microbial taxa. by Román Zapién-Campos (9592478)

“…(<b>A</b>) When hosts are colonized slowly, the trajectories maintain a mean frequency given by the pool of colonizers (<i>p</i>_<i>i</i>), but show an increased standard deviation before full colonization, which decreases later to reach <i>x</i>_<i>i</i> ≈ <i>p</i>_<i>i</i> at the long-term equilibrium. …”

The impact of haulroad geometric parameters on open pit mine strip ratio by Douglas Alexandre Gonçalves Alegre (6302681)