A Single Mutation in Chikungunya Virus Affects Vector Specificity and Epidemic Potential by Konstantin A Tsetsarkin (78536)

“…</em> Using viral infectious clones of the Reunion strain and a West African strain of CHIKV, into which either the E1–226 A or V mutation was engineered, we demonstrated that the E1-A226V mutation was directly responsible for a significant increase in CHIKV infectivity for <em>Ae. albopictus</em>, and led to more efficient viral dissemination into mosquito secondary organs and transmission to suckling mice. …”

Reduced LFS-LTD but normal mGluR-LTD, HFS-LTP, TBS-LTP, and PSD density and morphology in the <i>Grin2b</i>^{<i>+/C456Y</i>} hippocampus. by Wangyong Shin (6793040)

Osteoblast migration speed shows shear stress dependence but only for a short period after the onset of the flow. by Brandon D. Riehl (3749659)

“…<p>(a) MC3T3-E1 osteoblasts under fluid flows showed peak migration speeds after the flow onset, which then decreased. …”

Diffusion tractography of the subcortical auditory system in a postmortem human brain by Kevin Sitek (4242859)

Laboratory colonization of VK mosquitoes. by Kelsey L. Adams (12859609)

Acoustic Divergence with Gene Flow in a Lekking Hummingbird with Complex Songs by Clementina Gonzalez (627306)

Regulation of a stable patch size through positive and negative feedbacks. by Bita Khalili (5540561)

“…(F) Normalized frequency of observed simultaneous patches in WT, Ste6 overexpression and Gap1 overexpression cells. We note that the patch intensity decreases in Gap1 overexpression cells (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006317#pcbi.1006317.s009" target="_blank">S6A Fig</a>) while our threshold for patch detection is the same as wt cells; thus we cannot exclude the possibility of more patches in Gap1 overexpression cells below the detection threshold.…”

Image_1_Ophthalmic findings of congenital insensitivity to pain with anhidrosis with a novel neurotrophic tyrosine kinase receptor type 1 gene mutation: A case report.JPEG by Rong Zhu (172093)

“…<p>We report a case of congenital insensitivity to pain with anhidrosis (CIPA) with a novel neurotrophic tyrosine kinase receptor type 1 (NTRK1) gene mutation. …”

OsNF-YAs suppress JA signaling. by Xiaoxiang Tan (12542842)

Spheroid size changes due to primary mucus reduction hits and mucus changes due to primary swell hits. by Pranjali Beri (14945400)

<b>Effect of a Dietary Intervention on Insulin Requirements and Glycemic Control in Type 1 Diabetes: </b><b>A 12-Week Randomized Clinical Trial</b> by Hana Kahleova (618836)

Pharmacological characterization of the UT-mediated inhibition of the GABA_AR currents. by Laurence Desrues (167370)

“…<p>(A) Whole-cell current response to Iso (10⁻⁴ M, 2 s) recorded in the absence or presence of the benzodiazepine site inverse agonist DMCM (10⁻⁵ M), <i>h</i>UII and URP (10⁻⁸ M, each), or UT antagonists [Orn⁵]-URP and palosuran (10⁻⁶ M, each) in CHO expressing α₂, β₃ and γ₂ subunits. …”

Counterion Blockade in a Heterogeneously Charged Single-File Water Channel by Shusong Zhang (470905)

“…We rationalize the ionic transport using 1D Kramers’ escape theory framework, which describes nonlinear ionic current and the impact of surface charge density on the <i>I</i>–<i>V</i> curves. …”

Immunohistochemical staining in each group. by Yue Yang (52715)

“…<p>Increase in the frequency with same amount of treadmill exercise decreased the MIA-induced degradation of COL2A1 in articular cartilage and reduced the expression of MMP-13 and NF-κB p65. …”

Supplementary Material for: Effects of wearing hearing aids on gait and cognition: A pilot study by figshare admin karger (2628495)

“…Furthermore, reduced fear of falling and increased WHO-5 scores were observed after one year of HA use. …”

The geometry of the lactation curve based on Wood's equation: a two-step prediction by Jhone Gleison de Oliveira (10446485)

Kaplan Meier curves of OS and PFS according to d-dimer values comparing OS rates between patients with D-dimer levels ≤ 0.3 µg/mL and those with levels > 0.3 µg/mL. by Huriye Senay Kiziltan (22298378)

CPA treatment lowered activated caspase 3 and GFAP levels while DPCPX increased activated Caspase 3 and GFAP levels. by Manuel Soliño (5410001)

“…F) Quantification of C3a by WB. DPCPX produced a highly significant rise in C3a relative density compared to CTL (1.85±0.5 vs 1.01±0.07; unpaired Student´s t-test; p<0.01; n = 4), **p<0.01.…”

A comprehensive study of glucose and oxygen gradients in a scaled-down model of recombinant HuGM-CSF production in thermoinduced <i>Escherichia coli</i> fed-batch cultures by Greta I. Reynoso-Cereceda (18501789)

“…</p> <p></p><p>Thermoinduced recombinant <i>E. coli</i> grew less in a two-compartment scale-down model.</p><p>Heat-inducible <i>E. coli</i> cultures at a large scale significantly decrease recombinant protein production.…”

Succinate Dehydrogenase Is a Direct Target of Sirtuin 3 Deacetylase Activity by Lydia W. S. Finley (209240)

“…</p> <h3>Methodology/Principal Findings</h3><p>In this study, we performed a proteomic screen to identify SIRT3 interacting proteins and identified several subunits of complex II and V of the electron transport chain. …”