The functional consequences of nsSNPs and prediction of disease-associated nsSNPs in human TYR gene. حسب Wei Fan (109074)

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations حسب Hui Li (32376)

"…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …"

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations حسب Hui Li (32376)

"…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …"

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations حسب Hui Li (32376)

"…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …"

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations حسب Hui Li (32376)

"…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …"

Percentage survival at different time intervals compared to control and LD 50 determination and absorbance [OD] at 48 h, 72 h using MTT assay. حسب Manoj Limbraj Yellurkar (11467219)

الموضوعات:

Adjusted association of demographic factors with SDOH scores among Arkansans overall and by race and ethnicity from September 5, 2020 to December 18, 2020^a^,<s... حسب Jenil R. Patel (3639451)

Ludmila Belayev 12-point scoring between groups. حسب Guangxiao Ni (19713106)

الموضوعات:

Klf5 expression is down-regulated in the ruptured human and experimental AAA. حسب Dong Ma (584680)

Human cerebral organoids treated with VPA show a decreased size, impaired neurogenesis, and induction of senescence in NE cells. حسب Muriel Rhinn (406515)

Deep crypt secretory (DCS) cells are predominantly distributed in the proximal colon, with a progressive decrease towards the distal colon. حسب Daisuke Sugahara (2047696)

Population dynamics modeling of split^50cM <i>ClvR</i> V1 drive introduced at different release percentages, and an example illustrating the role that LOF alleles play in... حسب Georg Oberhofer (3401438)

"…A large number of individuals WT at each of these loci is now introduced into the modified population (release of 50%). …"

Exposure to low CO₂ levels decreases ER cholesterol levels. حسب Nityanand Bolshette (17396845)

"…<b>(C)</b> Total cholesterol quantification (with fluorometric assay kit) in NIH3T3 cells depleted with sterols for 2 h or exposed to different CO₂ levels for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, **<i>P</i> < 0.01, nonsignificant (ns), two-sided Student’s <i>t</i> test). <b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …"

Treatment with TDF decreased cell viability and induced morphological changes in hepatic stellate cells. حسب Sung Won Lee (222509)

Prb1 overexpression decreased APCs in ESCRT-mutant cells after nitrogen starvation. حسب Zulin Wu (4451572)

"…</b> The accumulation of GFP-Atg8-labeled APCs in ESCRT- mutant (<i>snf7Δ</i>, <i>vps4Δ</i>) cells decreased with Prb1 overexpression. The indicated cells were transformed with a Prb1-expression plasmid or the empty vector (pRS415, ∅), grown, and examined as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010431#pgen.1010431.g007" target="_blank">Fig 7A</a>. …"

Image 1_Exploration of the diagnostic and prognostic roles of decreased autoantibodies in lung cancer.tif حسب Ying Ye (72583)

Exploration of up- and down-regulated genes at each UV irradiation time-point. حسب Seon-Pil Jin (17364626)

All-cause gastroenteritis hospitalisations of children decreased after the introduction of rotavirus vaccine in Stockholm حسب Selma Olsson-Åkefeldt (11500789)

Conditional ablation of <i>Ybx1</i> leads to a reduction in cortical progenitor cell pool and a decrease in cortical thickness. حسب Jian Zhang (1682)

Image_1_Electroencephalographic Evidence for Individual Neural Inertia in Mice That Decreases With Time.JPEG حسب Andrzej Z. Wasilczuk (11945885)

"…EEG was measured after induction of and emergence from isoflurane administered near the EC₅₀ dose for loss of righting in genetically inbred mice on a timescale that minimizes pharmacokinetic confounds. …"