Efficacy of Lapatinib in Therapy-Resistant HER2-Positive Circulating Tumor Cells in Metastatic Breast Cancer by Sofia Agelaki (74455)

“…CTC monitoring was performed by immunofluorescent microscopy using cytospins of peripheral blood mononuclear cells (PBMCs) double stained for HER2 or EGFR and cytokeratin.</p><p>Results</p><p>A total of 120 cycles were administered in 22 patients; median age was 62.5 years, 15 (68.2%) patients were post-menopausal and 20 (90.1%) had HER2-negative primary tumors. …”

DataSheet1_The Involvement of TRIB3 and FABP1 and Their Potential Functions in the Dynamic Process of Gastric Cancer.XLSX by Songyi Liu (11589508)

“…Hp infection was significantly associated with the decreased expression of TRIB3 and FABP1. In addition, the diagnostic efficiency of the combination of these two indicators to diagnose EGC was higher than that of a single indicator. …”

Administration of anatabine inhibits pro-inflammatory cytokines but does not affect the titer of circulating anti-MOG antibodies. by Daniel Paris (286121)

“…B) Anatabine inhibits the production of pro-inflammatory cytokines in the serum of EAE mice. A significant elevation of TNF-α (Mann-Whitney U = 16.5, Z = −2.22, P = 0.026), IL-1β (Mann-Whitney U = 0, Z = −3.506, P<0.001), IL-6 (Mann-Whitney U = 3, Z = −3.271, P<0.001), IFN-γ (Mann-Whitney U = 16.5, Z = −2.219, P = 0.026) and IL-17 (Mann-Whitney U = 7, Z = −2.958, P = 0.003) was observed in the serum of EAE mice (placebo) compared to control non-immunized mice. …”

Image_2_The Increased Risk of Thyroid Cancer-Specific Mortality With Tumor Size in Stage IVB Patients.PNG by Junyi Zhang (290426)

“…</p><p>Methods: One thousand three hundred and forty-five patients (620 males and 725 females) with initial distant metastasis over 55 years between 2004 and 2016 from Surveillance, Epidemiology, and End Results databases were investigated, with a median follow-up time of 23 months [interquartile range (IQR), 5–56 months] and a median age of 70 years (IQR, 63–77 years). …”

Neuroprotection by CPE-ΔN involves AKT and ERK signaling pathways. by Xiao-Yan Qin (666512)

“…Data shown represent one experiment. n = 4/group (A); 5/group (B); 4/group (C); 5/group (D). Values are mean ± SEM, one-way ANOVA followed by Tukey test, *p<0.05.…”

Household air pollution and risk of pulmonary tuberculosis in HIV-Infected adults by Patrick D.M.C. Katoto (17807086)

“…Participants reporting cooking for >3h/day and ≥2 times/day and ≥5 days/week were more likely to have PTB (aOR 1·36; 95%CI 1·06-1·75) than those spending less time in the kitchen. …”

General participant characteristics. by Josephine Grandt (21512356)

“…GOBP analyses revealed an increase in pro-inflammatory and pro-fibrotic genes in NAFLD and cirrhosis, as well as a decrease in genes related to metabolism. Data were made browsable using two web-based apps. …”

Supplementary Material for: Calcium-Alkali Syndrome Associated with Hypoparathyroidism Following Total Thyroidectomy by Kuroya S. (8343321)

“…We defined hypercalcemia as a corrected serum calcium level (cCa) ≥10.5 mg/dL, metabolic alkalosis as a difference in serum sodium and serum chloride ([sNa-sCl]) ≥39 mEq/L, and renal impairment as a ≥50% increase in serum creatine and/or ≥35% decrease in estimated glomerular filtration rate (eGFR) compared to baseline. …”

TLR7 Influences Germinal Center Selection in Murine SLE by Alexis Boneparth (707054)

“…In addition, although all chimeras preferentially selected 3H9/Vκ5 encoded B cells into the germinal center and plasma cell compartments, 3H9 male <i>Yaa</i> chimeras had a more diverse repertoire and positively selected the 3H9/Vκ5-48/Jκ4 pair that confers high affinity anti-cardiolipin activity. …”

DataSheet2_The Involvement of TRIB3 and FABP1 and Their Potential Functions in the Dynamic Process of Gastric Cancer.ZIP by Songyi Liu (11589508)

“…Hp infection was significantly associated with the decreased expression of TRIB3 and FABP1. In addition, the diagnostic efficiency of the combination of these two indicators to diagnose EGC was higher than that of a single indicator. …”

Data_Sheet_1_Highly Efficient Deep Blue Luminescence of 2-Coordinate Coinage Metal Complexes Bearing Bulky NHC Benzimidazolyl Carbene.pdf by Rasha Hamze (1987576)

“…All the complexes emit in the deep blue region (~430 nm) with relatively narrow spectra (full width at half maximum = 44 nm, 2,300 cm⁻¹) characterized by vibronic fine structure in nonpolar media (methylcyclohexane at room temperature), and with high photoluminescence quantum yields (Φ_PL > 80%) and radiative rate constants (k_r ~ 7.8 × 10⁵ s⁻¹). The luminescence is solvatochromic, undergoing a red-shift in a polar solvent (CH₂Cl₂) at room temperature that are accompanied by a decrease in quantum yields (Φ_PL < 23%) and radiative rate constants (k_r < 4.0 × 10⁴ s⁻¹), whereas the non-radiative rate constants remain nearly constant (k_nr ~ 1.0 × 10⁵ s⁻¹). …”

Image_1_The Increased Risk of Thyroid Cancer-Specific Mortality With Tumor Size in Stage IVB Patients.PNG by Junyi Zhang (290426)

“…</p><p>Methods: One thousand three hundred and forty-five patients (620 males and 725 females) with initial distant metastasis over 55 years between 2004 and 2016 from Surveillance, Epidemiology, and End Results databases were investigated, with a median follow-up time of 23 months [interquartile range (IQR), 5–56 months] and a median age of 70 years (IQR, 63–77 years). …”

Data_Sheet_1_Chinese Home-Based Cardiac Rehabilitation Model Delivered by Smartphone Interaction Improves Clinical Outcomes in Patients With Coronary Heart Disease.PDF by Jing Ma (24574)

“…</p><p>Conclusions: The Chinese HBCR model using smartphone interaction is a safe and effective approach to decrease cardiovascular risks of patients with CHD and improve patients' wellness.…”

Sequence conservation in hemagglutinin groups and subtypes. by Nicola Clementi (174058)

“…*Recombinant HA from H1N1 A/South Carolina/1/1918 pandemic strain was previously shown to be bound by PN-SIA28 <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0028001#pone.0028001-Burioni2" target="_blank">[19]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0028001#pone.0028001-Burioni3" target="_blank">[20]</a>; analogously, recombinant HA from H5N1 A/Cygnus Olor/Italy/742/2005 was recognized by PN-SIA28 (data not shown). # H1N1 A/New Caledonia/20/1999 was previously shown to be neutralized by PN-SIA28 as Fab fragment <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0028001#pone.0028001-Burioni2" target="_blank">[19]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0028001#pone.0028001-Burioni3" target="_blank">[20]</a>.…”

Roles of individual genetic factors during repair of DSBs with non-cohesive ends generated by co-expression of I-SceI with Trex2. by Nicole Bennardo (93380)

“…(B) Trex2 expression causes a decrease in HDR in cells deficient in Nbs1 and Brca1, but an increase in HDR in cells deficient in Xrcc4 and Msh2. …”

Robotic Left Upper Lobectomy by Stephanie G. Worrell (4876525)

“…She then had a completion robotic lobectomy with mediastinal lymph node dissection of stations 5, 6, 7, and L9. …”

Metabolite profiling of MTG16-expressing cells. by Parveen Kumar (428921)

“…The loading plot for the predictive variation (p<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0068502#pone.0068502-Feinstein1" target="_blank">[1]</a>), describing which metabolites that differ in level between non-induced and induced cells, reveals that mainly amino acid levels are decreased in doxycycline induced cells. …”

RNAIII regulates the levels of extracellular proteins at 6 h and 12 h. by Yu Liu (6938)

“…The results of SDS-PAGE showed that the extracellular proteins of <i>ΔRNAIII</i> were decreased in comparing with WT at 6 h and 12 h. 1,4,7: wild type; 2,5,8: <i>ΔRNAIII</i> (RNAIII deletion mutant); 3,6,9: ΔRNAIIIR (the restoration of RNAIII in <i>ΔRNAIII</i>). …”

Microsatellite Interruptions Stabilize Primate Genomes and Exist as Population-Specific Single Nucleotide Polymorphisms within Individual Human Genomes by Guruprasad Ananda (599807)

“…Modeling the adenomatous polyposis coli tumor suppressor gene sequence, we observed that a single base substitution interruption reduced strand slippage error rates five- to 50-fold, relative to a perfect repeat, during synthesis by DNA polymerases α, β, or η. …”

Engulfment simulation by Mathieu Emily (39337)