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741
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742
Shortening of mTL anticipates accumulation of DDR markers, decrease in cell proliferation and increase in apoptotis with age.
Published 2016“…All tissues show a significant increase in cells bearing five or more γH2AX foci by 12 months of age in <i>tert</i><sup>-/-</sup> zebrafish (panels b, d) and by 36 months in WT zebrafish (panels a, c and e). …”
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743
<i>In vivo</i> treatment with entinostat decreases Foxp3 expression in Tregs and inhibits Tregs function.
Published 2012“…Cells were harvested from spleens and lymph nodes. A, <i>In vivo</i> entinostat treatment decreased the expression level of Foxp3 in CD4<sup>+</sup>Foxp3<sup>+</sup> (Treg) cells. …”
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744
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745
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746
Loss of Rumi leads to intracellular accumulation and decreased IRS levels of Eys in a temperature dependent manner at the mid-pupal stage.
Published 2014“…The scale bar in A applies to A–G′ and is 5 µm. (A,A′) A wild-type ommatidium at 55% PD raised at 18°C. …”
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747
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748
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749
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750
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751
Rac1 activity rapidly decreases upon cell-cell adhesion in 3-D cell aggregates.
Published 2011“…High levels of active Rac1 at 0 minutes rapidly decreased (∼66%) within 5 minutes of cell-cell adhesion, and declined to a baseline level by 30 minutes (A). …”
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752
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753
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754
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755
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756
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757
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758
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759
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760