DataSheet1_Necroptotic kinases are involved in the reduction of depression-induced astrocytes and fluoxetine’s inhibitory effects on necroptotic kinases.pdf by Salman Zeb (12897155)

“…Treatment with fluoxetine (FLX) for 5 weeks improved chronic unpredictable mild stress-induced mouse depressive-like behaviors; simultaneously, fluoxetine inhibited depression-induced necroptotic kinase activation, reversed the reduction in astrocytes and astrocytic necroptosis and dysfunction, decreased inflammatory cytokines and upregulated brain-derived neurotropic factors and 5-HT1A levels. …”

The Repetitive Domain of ScARP3d Triggers Entry of <em>Spiroplasma citri</em> into Cultured Cells of the Vector <em>Circulifer haematoceps</em> by Laure Béven (123889)

“…Inhibition tests using anti-Rep3d antibodies and competitive assays with recombinant Rep3d both resulted in a decrease of insect cells invasion by the spiroplasmas. …”

Image_2_Folic Acid Fortification Prevents Morphological and Behavioral Consequences of X-Ray Exposure During Neurulation.TIFF by Kai Craenen (9960446)

“…These findings coincided with the observation of a reduction in thickness of the retinal ganglion cell and nerve fiber layer, and a decreased axial length of the eye following exposure to 0.5 Gy. …”

Image_3_Folic Acid Fortification Prevents Morphological and Behavioral Consequences of X-Ray Exposure During Neurulation.TIFF by Kai Craenen (9960446)

“…These findings coincided with the observation of a reduction in thickness of the retinal ganglion cell and nerve fiber layer, and a decreased axial length of the eye following exposure to 0.5 Gy. …”

Table_1_Folic Acid Fortification Prevents Morphological and Behavioral Consequences of X-Ray Exposure During Neurulation.DOCX by Kai Craenen (9960446)

“…These findings coincided with the observation of a reduction in thickness of the retinal ganglion cell and nerve fiber layer, and a decreased axial length of the eye following exposure to 0.5 Gy. …”

Muscovite ⁴⁰Ar/³⁹Ar ages help reveal the Neogene tectonic evolution of the southern Annapurna Range, central Nepal by Aaron J. Martin (671213)

“…</em> 7 Ma and ages from several samples in the east are <em>c.</em> 5–2 Ma, indicating a decline of 2–5 Ma towards the east. …”

Modeled HIV incidence under different scenarios. by Sun Bean Kim (541738)

“…A-4. Ratio of incident HIV cases (KX) compared all interventions (scenario 5) with current situation. …”

SNX-3-mediated CIE recycling tubules do not converge into the classical EEA-1-labeled sorting endosomes. by Yangli Tian (4871416)

“…(F,G) The membrane-to-cytosol ratio of EEA1 decreased in SNX3-overexpressed Hela cells. Hela cells overexpressing empty or EGFP-SNX3 vector were separated into a supernatant (S) fraction and a pellet (P) fraction and were stained for endogenous EEA1, TfR (as a control of transmembrane protein), GAPDH, and ectopically expressed EGFP-SNX3 (F). …”

Longitudinal MRI study of changes in BTB permeability and rCBV of brain metastases. by Heling Zhou (368949)

“…All the tumors except one (yellow arrowhead) still kept BTB intact at week 4. rCBV maps were created and rCBV values of the tumors were presented in the table (<b>B</b>). <b>C.</b> A total of 32 lesions in 5 animals were seen on both scans of weeks 3 and 4. rCBV of brain metastases (solid) was initially similar to that of contralateral normal brain (open; mean  = 1.05±0.05 (se) vs. 0.96±0.04), but decreased significantly (p<0.05) and became significantly lower as compared to their contralateral normal brain in the late scan (mean  = 0.88±0.06 vs. 1.00±0.06; p<0.05).…”

Loss of <i>Nf1</i> results in reduced bone mineral density (BMD), volume (BV), and trabecular architecture in <i>Col2.3Cre⁺;Nf1^flox/−</i> mice <i>in vivo</i>.... by Xiaohua Wu (120920)

“…(<b>C</b>) Micro-CT (μCT) scans were performed on the distal femurs of 4 month old WT (n = 5), <i>Nf1+/−</i> (n = 5), <i>Col2.3Cre⁺;Nf1^flox/flox</i> (n = 5) and <i>Col2.3Cre⁺;Nf1^flox/−</i> (n = 5) mice. …”

Data_Sheet_1_N6-Methyladenine in Eukaryotic DNA: Tissue Distribution, Early Embryo Development, and Neuronal Toxicity.PDF by Sara B. Fernandes (10860612)

“…Furthermore, exposure to a neurotoxic environmental pollutant during the same early life period may led to a decrease in the levels of this modification in female rats. …”

ROP18 directly phosphorylates Irga6 at T102 and T108 in vitro. by Tobias Steinfeldt (154465)

“…<p>(A) Bacterially expressed, purified wt or T102A and T108A mutant Irga6 proteins (300 ng) were coincubated with bacterially expressed, purified GST-ROP18-Ty (10 µl, 5 µl, 1.7 µl respectively; 1 µl ∼20 ng) in the presence of γ³²P-ATP in vitro. …”

Redox Active Cage for the Electrochemical Sensing of Anions by Valeria Amendola (1966936)

“…Such a behavior parallels the gradual decrease of the equilibrium constant for anion inclusion into the [Co^II(<b>1</b>)]⁵⁺ receptor.…”

The TYDQYI-motif in the SBD of PauR is essential for the overall functionality of the receptor and DAR-sensing. by Sophie Brameyer (731567)

“…<p>The most drastic effects on DAR-sensing were gained with the replacement of S38A, T62A, Y66A, D75A and D75N in the SBD of PauR and a decreased effect on DAR-sensing were gained with the replacement of Y90C and I113S in PauR (lower right quadrant). …”

The effects of Hb binding site number and strength on noise. by David M. Holloway (95831)

“…(C) Simulation with 6 Bcd sites and 2 Hb sites, compare to (D) lacZ in a pThb5 embryo (promoter indicated by green arrows in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1001069#pcbi-1001069-g002" target="_blank">Figure 2A</a>). …”

Conducting low frequency RNS examinations bilaterally in control and MCAO rats. by Lei Zhang (38117)

“…<p>Representative images of consecutive low frequency RNS tests (5 Hz) in one MCAO rat at different time points are shown. …”

Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis by Lorena Fernandez-Mosquera (5077820)

“…</p> <p><b>Abbreviation</b>: ΔΨ_m: mitochondrial transmembrane potential; AMP: adenosine monophosphate; AMPK: AMP-activated protein kinase; ATG5: autophagy related 5; ATP: adenosine triphosphate; ATP6V0A1: ATPase, H+ transporting, lysosomal, V0 subbunit A1; ATP6V1A: ATPase, H+ transporting, lysosomal, V0 subbunit A; BSA: bovine serum albumin; CCCP: carbonyl cyanide-m-chlorophenylhydrazone; CREB1: cAMP response element binding protein 1; CTSD: cathepsin D; CTSF: cathepsin F; DMEM: Dulbecco’s modified Eagle’s medium; DMSO: dimethyl sulfoxide; EBSS: Earl’s balanced salt solution; ER: endoplasmic reticulum; FBS: fetal bovine serum; FCCP: carbonyl cyanide-p-trifluoromethoxyphenolhydrazone; GFP: green fluorescent protein; GPN: glycyl-L-phenylalanine 2-naphthylamide; LAMP1: lysosomal associated membrane protein 1; MAP1LC3B/LC3B: microtubule associated protein 1 light chain 3 beta; MCOLN1/TRPML1: mucolipin 1; MEF: mouse embryonic fibroblast; MITF: melanocyte inducing transcription factor; ML1N*2-GFP: probe used to detect PtdIns(3,5)P₂ based on the transmembrane domain of MCOLN1; MTORC1: mechanistic target of rapamycin kinase complex 1; NDUFS4: NADH:ubiquinone oxidoreductase subunit S4; OCR: oxygen consumption rate; PBS: phosphate-buffered saline; pcDNA: plasmid cytomegalovirus promoter DNA; PCR: polymerase chain reaction; PtdIns3P: phosphatidylinositol-3-phosphate; PtdIns(3,5)P₂: phosphatidylinositol-3,5-bisphosphate; PIKFYVE: phosphoinositide kinase, FYVE-type zinc finger containing; P/S: penicillin-streptomycin; PVDF: polyvinylidene fluoride; qPCR: quantitative real time polymerase chain reaction; RFP: red fluorescent protein; RNA: ribonucleic acid; SDS-PAGE: sodium dodecyl sulfate polyacrylamide gel electrophoresis; shRNA: short hairpin RNA; siRNA: small interfering RNA; TFEB: transcription factor EB; TFE3: transcription factor binding to IGHM enhancer 3; TMRM: tetramethylrhodamine, methyl ester, perchlorate; ULK1: unc-51 like autophagy activating kinase 1; ULK2: unc-51 like autophagy activating kinase 2; UQCRC1: ubiquinol-cytochrome c reductase core protein 1; v-ATPase: vacuolar-type H+-translocating ATPase; WT: wild-type</p>…”

Image analyses of heterodimerization between TASK1 and TALK2. by Yoshiaki Suzuki (7037)

“…<b>(B)</b> FRET analysis based on acceptor photobleaching was carried out using a confocal microscope. YFP within the ROI 1–5 (white rectangles in the figures) in HEK293 cells co-expressing TASK1-YFP+CFP-TALK2 was selectively photobleached using a laser at 514 nm wavelength. …”

Table_1_Bioinformatics Analysis Identifies Potential Ferroptosis Key Genes in the Pathogenesis of Intracerebral Hemorrhage.DOCX by Tongye Liu (10931763)

“…Treadmill training increased the expression of anti-inflammatory molecules TNFAIP3 and SLC2A1 and reduced the expression of MAPK1, ATF4, and MAPK8, indicating that treadmill training may be utilized as antioxidant therapy to decrease neuronal ferroptosis. …”

Table_1_Bioinformatics Analysis Identifies Potential Ferroptosis Key Genes in the Pathogenesis of Intracerebral Hemorrhage.DOCX by Tongye Liu (10931763)

“…Treadmill training increased the expression of anti-inflammatory molecules TNFAIP3 and SLC2A1 and reduced the expression of MAPK1, ATF4, and MAPK8, indicating that treadmill training may be utilized as antioxidant therapy to decrease neuronal ferroptosis. …”